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GEN reports on enhancing the applications of qPCR Quantitative polymerase chain reaction (qPCR) technology is experiencing a surge of interest and rapid expansion as a result of advances such as instrumentation that pushes capacity to 1,536 wells and optimization-free multiplexing. view more (2009-11-19)
How RNA polymerase II gets the go-ahead for gene transcription All cells perform certain basic functions. Each must selectively transcribe parts of the DNA that makes up its genome into RNAs that specify the structure of proteins. view more (2009-10-12)
Test developed at UQ diagnosed Australia's first swine flu victim When the first cases of H1N1 Influenza (swine flu) were reported in Mexico in April, UQ researchers got to work developing a test to diagnose the virus. view more (2009-09-04)
Bird flu leaves the nest -- adapting to a new host Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. view more (2009-08-27)
A better test to detect DNA for diagnosing diease, investigating crimes Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. view more (2009-08-27)
Current hepatitis C treatments work equally well, UT Southwestern and national researchers report The three treatment combinations for clearing the most common form of the hepatitis C virus work equally well with similar side effects, UT Southwestern Medical Center researchers and their colleagues in 13 other institutions have found. view more (2009-08-07)
The 15-Minute Genome 2009 Industrial Physics Forum features faster, cheaper genome sequencing In the race for faster, cheaper ways to read human genomes, Pacific Biosciences is hoping to set a new benchmark with technology that watches DNA being copied in real time. view more (2009-07-28)
One secret to how TB sticks with you Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. view more (2009-07-10)
Faster, more cost-effective DNA test for crime scenes, disease diagnosis Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological research and other applications. view more (2009-07-09)
Molecular typesetting -- proofreading without a proofreader Researchers at the Universities of Leeds and Bristol (UK) have developed a model of how errors are corrected whilst proteins are being built. view more (2009-06-23)
New Piece Found in the Puzzle of Epigenetics A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
Tribble 3 can induce non-alcoholic fatty liver disease? Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. view more (2009-06-11)
Genetic pathway responsible for link between body clock disturbance and worsening arthritis The genes that regulate human circadian rhythm, or 'the body clock', are significantly disturbed in individuals with arthritis. view more (2009-06-11)
MIT, BU engineer cellular circuits that count events MIT and Boston University engineers have designed cells that can count and "remember" cellular events, using simple circuits in which a series of genes are activated in a specific order. view more (2009-05-29)
The challenges of avian influenza virus: Mechanism, epidemiology and control The latest special issue of Science in China Series C: Life Sciences focuses on the recent progress in the H5N1-related research field. view more (2009-05-22)
Caltech biologists find optimistic worms are ready for rapid recovery For the tiny soil-dwelling nematode worm Caenorhabditis elegans, life is usually a situation of feast or famine. Researchers at the California Institute of Technology (Caltech) have found that this worm has evolved a surprisingly optimistic genetic strategy to cope with these disparate conditions--one that could eventually point the way to new... view more... (2009-03-10)
RNA interference toward MMP-2 may be an effective therapeutic strategy for cancer The invasion or metastasis of pancreatic cancer has been known to be a complex process involving many molecular mechanisms, of which proteolytic degradation of extracellular matrix (ECM) exerted by matrix metalloproteinases (MMPs) was considered to be an essential step. view more (2009-03-09)
Proteasome inhibition affects epigenetic mechanisms Alcohol consumption causes alteration in several cellular mechanisms, and leads to inflammation, apoptosis, immunoresponse defect, and fibrosis. view more (2009-02-19)
Plant polymerases IV and V are special forms of Polymerase II It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA Polymerases IV and V (Pol IV and V), found only in plants, are actually specialized forms of RNA Polymerase II, an essential enzyme of all eukaryotic... view more... (2009-01-07)
Evolution in action: Our antibodies take 'evolutionary leaps' to fight microbes With cold and flu season in full swing, the fact that viruses and bacteria rapidly evolve is apparent with every sneeze, sniffle, and cough. A new report in the January 2009 issue of The FASEB Journal, explains for the first time how humans keep up with microbes by rearranging the genes that make antibodies to foreign invaders. This research fills... view more... (2009-01-06)
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