Recent Protease Current Events | Protease News
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Super sticky barnacle glue cures like blood clots Barnacles are a big problem for boats. Adhering to the undersides of vessels, carpets of the crustaceans can increase fuel consumption by as much as 25%. view more (2009-10-16)
Major discovery opens door to leishmania treatment Leishmania is a deadly parasitic disease that affects over 12 million people worldwide, with more than 2 million new cases reported every year. view more (2009-10-07)
How Proteins Talk to Each Other Investigators at Burnham Institute for Medical Research (Burnham) have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). view more (2009-09-22)
Yes-associated protein: Early diagnosis of gastric carcinoma Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator. view more (2009-09-16)
Researchers restore missing protein in rare genetic brain disorder UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death in human... view more... (2009-09-08)
Current hepatitis C treatments work equally well, UT Southwestern and national researchers report The three treatment combinations for clearing the most common form of the hepatitis C virus work equally well with similar side effects, UT Southwestern Medical Center researchers and their colleagues in 13 other institutions have found. view more (2009-08-07)
HIV integrase inhibitor effective for patients beginning antiretroviral treatment A member of a new class of antiretroviral drugs is safe and effective for patients beginning treatment against HIV, according to researchers who have completed a two-year multisite phase III clinical trial comparing it with standard antiretroviral drugs. view more (2009-08-03)
UCSF researchers identify new drug target for Kaposi's Sarcoma UCSF researchers have identified a new potential drug target for the herpes virus that causes Kaposi's sarcoma, re-opening the possibility of using the class of drugs called protease inhibitors against the full herpes family of viruses, which for 20 years has been deemed too difficult to attain. view more (2009-07-30)
What is the role of reactive oxygen species in ethanol-mediated cell death of polarized hepatic cells? Liver disease that results as a consequence of alcohol abuse is a major medical problem worldwide. Ethanol consumption leads to a variety of liver alterations including the accumulation of fat, inflammation of the liver, as well as the presence of scar tissue. view more (2009-06-15)
Locking Parasites in Host Cell Could Be New Way to Fight Malaria, Penn Study Shows Researchers at the University of Pennsylvania have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases they cause. view more (2009-04-06)
HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress... view more... (2009-03-26)
Cathepsin B increases apoptosis in fulminant hepatic failure The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis. view more (2009-03-20)
New Stanford list of HIV mutations vital to tracking AIDS epidemic In a collaborative study with the World Health Organization and seven other laboratories, researchers at the Stanford University School of Medicine have compiled a list of 93 common mutations of the AIDS virus associated with drug resistance that will be used to track future resistance trends throughout the world. view more (2009-03-06)
New information points to safer methadone use for treatment of pain and addiction New findings may significantly improve the safety of methadone, a drug widely used to treat cancer pain and addiction to heroin and other opioid drugs, according to researchers at Washington University School of Medicine in St. Louis and the University of Washington in Seattle. view more (2009-03-03)
Monash research breakthrough to treat malaria A team of Monash University researchers led by Professor James Whisstock has made a major breakthrough in the international fight against malaria, which claims the life of a child across the world every 30 seconds. view more (2009-02-03)
Scientists make malaria parasite work to reveal its own vulnerabilities Researchers seeking ways to defeat malaria have found a way to get help from the parasite that causes the disease. view more (2009-01-29)
Jefferson scientists discover a key protein regulator of inflammation and cell death Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation. view more (2009-01-23)
Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis? Severe acute pancreatitis (SAP) remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing multi-organ dysfunction syndrome (MODS) with an increased mortality rate. view more (2008-12-30)
Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis? Severe acute pancreatitis (SAP) remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing multi-organ dysfunction syndrome (MODS) with an increased mortality rate. view more (2008-12-29)
Study of placenta unexpectedly leads to cancer gene University of Rochester Medical Center scientists discovered a gene mutation that impairs the placenta and also is influential in cancer development, according to a study published online December 16, 2008, in the journal PLoS (Public Library of Science) Biology. view more (2008-12-17)
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