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Methylmercury warning
Recent studies hint that exposure to the toxic chemicals, such as methylmercury can cause harm at levels previously considered safe.   view more (2008-10-29)

Scientists identify new gene responsible for puberty disorders
A new gene responsible for some puberty disorders has been identified by Medical College of Georgia researchers.    view more (2008-10-28)

Rare genetic disorder gives clues to autism, epilepsy, mental retardation
A rare genetic disorder called tuberous sclerosis complex (TSC) is yielding insight into a possible cause of some neurodevelopmental disorders: structural abnormalities in neurons, or brain cells.   view more (2008-09-24)

Iron-moving malfunction may underlie neurodegenerative diseases, aging
A glitch in the ability to move iron around in cells may underlie a disease known as Type IV mucolipidosis (ML4) and the suite of symptoms---mental retardation, poor vision and diminished motor abilities---that accompany it, new research at the University of Michigan shows.   view more (2008-09-23)

Aberrations in region of chromosome 1q21.1 associated with broad range of disorders in children
Researchers have discovered a submicroscopic aberration in a particular region of human chromosome 1q21.1 that appears to be associated with a variety of developmental disorders in children.   view more (2008-09-11)

Pregnancy situations have impact on brain development in pre-term infants
Brain development in infants who are born very prematurely is still incomplete. Factors that cause premature birth may have an impact on the development of the premature infant's brain both during pregnancy and later on after birth.   view more (2008-08-28)

UC Davis researchers define characteristics, treatment options for XXYY syndrome
Researchers at the UC Davis M.I.N.D. Institute and The Children's Hospital in Denver have conducted the largest study to date describing the medical and psychological characteristics of a rare genetic disorder in which males have two "X" and two "Y" chromosomes, rather than the... view more (2008-08-25)

Model for Angelman syndrome developed by University of Texas at Austin biologists
A model for studying the genetics of Angelman syndrome, a neurological disorder that causes mental retardation and other symptoms in one out of 15,000 births, has been developed by biologists at The University of Texas at Austin.   view more (2008-08-15)

Researchers find differences in swallowing mechanism of Rett syndrome patients
Researchers at Wake Forest University Baptist Medical Center have found that the reflux and swallowing problems that are common symptoms in patients with Rett syndrome and other neurological impairments, may be caused by a different mechanism than they are in healthy individuals.   view more (2008-08-05)

Imiquimod, an immune response modifier, is dependent on the OGF-OGFr signaling pathway
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor... view more (2008-07-28)

Drug reverses mental retardation caused by genetic disorder
UCLA researchers discovered that an FDA-approved drug reverses the brain dysfunction inflicted by a genetic disease called tuberous sclerosis complex (TSC).   view more (2008-06-23)

New research on mutation in yeast can enhance understanding of human diseases
Yeast, a model organism heavily relied upon for studying basic biological processes as they relate to human health, mutates in a distinctly different pattern than other model organisms, a finding that brings researchers closer to understanding the role of evolutionary genetics in human diseases and... view more (2008-06-20)

New gene discovered for new form of intellectual disability
The Centre for Addiction and Mental Health (CAMH) has discovered a new form of intellectual disability involving mental retardation (MR) along with the eye defect retinitis pigmentosa (RP).   view more (2008-04-24)

Drosophila drug screen for fragile X syndrome finds promising compounds and potential drug targets
Scientists using a new drug screening method in Drosophila (fruit flies), have identified several drugs and small molecules that reverse the features of fragile X syndrome -- a frequent form of mental retardation and one of the leading known causes of autism.   view more (2008-03-10)

Genetic mutation increases risk of preterm birth
Genetic mutations in the Toll-like receptor 4 (TLR4) gene appear to have significant association with inflammatory injury to the placenta and developing baby, researchers from the University of Pittsburgh's department of obstetrics, gynecology and reproductive sciences report at the 28th annual... view more (2008-02-04)

Discovery of new cause of mental retardation simplifies search for treatments
2 to 3 children in 100 are born with a mental handicap. This can be caused by a genetic defect, but in 80% of the cases scientists do not know which genes are responsible.   view more (2008-01-25)

UNC, Duke lead first statewide shaken baby prevention research project in US
Child abuse prevention experts from the University of North Carolina at Chapel Hill Injury Prevention Research Center and School of Medicine and Duke University Medical Center will undertake a $7 million statewide shaken baby prevention project.   view more (2008-01-17)

Researchers uncover mechanisms of common inherited mental retardation
Researchers at UT Southwestern Medical Center are uncovering how brain cells are affected in Fragile X syndrome, the most common cause of inherited mental retardation and the most common genetic cause of autism.   view more (2008-01-09)

Better access to cool caps improves outcomes, lowers cost of treating asphyxia in newborns
When newborns suffering from a form of asphyxia at birth have better access to head cooling devices, fewer will face a lifetime of debilitating and costly health complications, according to researchers at Beth Israel Deaconess Medical Center (BIDMC).   view more (2008-01-08)

MIT corrects inherited retardation, autism in mice
Researchers at MIT's Picower Institute for Learning and Memory have corrected key symptoms of mental retardation and autism in mice.   view more (2007-12-20)

Fragile X retardation syndrome corrected in mice
Researchers working with mice have significantly alleviated a wide range of abnormalities due to fragile X syndrome by altering only a single gene, countering the effects of the fragile X mutation.   view more (2007-12-20)

Study finds first-ever genetic animal model of autism
By introducing a gene mutation in mice, investigators have created what they believe to be the first accurate model of autism not associated with a broader neuropsychiatric syndrome, according to research presented at the American College of Neuropsychopharmacology annual meeting.   view more (2007-12-10)

MIT: Missing protein may be key to autism
A missing brain protein may be one of the culprits behind autism and other brain disorders, researchers at MIT's Picower Institute for Learning and Memory report in the Dec. 6 issue of Neuron.   view more (2007-12-06)

Synchrotron radiation illuminates how babies' protective bubble bursts
Researchers at the University of Reading, School of Pharmacy have developed an important new technique to study one of the most common causes of premature birth and prenatal mortality.   view more (2007-11-07)

One shot of gene therapy spreads through brain in animal study
By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain-after one injection of gene therapy. If these results in animals can be realized in people, researchers may have a potential method for gene therapy to treat... view more (2007-10-09)

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