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New therapy for vasculitis will help patients avoid infertility and cancer Researchers have identified that Rituxan, a drug previously approved for the treatment of non-Hodgkin's B cell lymphoma and rheumatoid arthritis, can treat severe ANCA-associated vasculitis as effectively as cyclophosphamide, the current standard therapy. view more (2009-10-19)
Stanford study identifies cellular mechanism that causes lupuslike symptoms in mice Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease. view more (2009-10-19)
Infective endocarditis: An old but changing disease Infective endocarditis (IE) is a severe form of valve disease characterized by infection located in the valves of the heart. view more (2009-08-31)
Winter- and spring-onset RA patients have worse 6 month outcomes than those with summer onset When a patient's first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7],... view more... (2009-06-12)
Better access to info and dialogue with HCPs on sexual issues for rheumatology patients Patients with rheumatic diseases want more information and better communication with healthcare professionals on the sexual issues related to their conditions. view more (2009-06-12)
Over half of people with rheumatoid arthritis have periodontitis Over half (56%) of people with rheumatoid arthritis (RA) also have periodontitis (a chronic inflammatory disease of the gum and surrounding ligaments and bones that hold the teeth in place), displaying fewer teeth than healthy matched controls, high prevalence of oral sites presenting dental plaque and advanced attachment loss (the extent of... view more... (2009-06-12)
Subclinical markers predict relapse in juvenile idiopathic arthritis post methotrexate withdrawal Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status. view more (2009-06-11)
Model for new generation of blood vessels challenged In-growth and new generation of blood vessels, which must take place if a wound is to heal or a tumor is to grow, have been thought to occur through a branching and further growth of a vessel against a chemical gradient of growth factors. view more (2009-06-02)
Ultrasound Changes Care of Some Patients with Rheumatic Conditions Ultrasound can be used to make an appropriate decision regarding care for patients with rheumatic conditions involving the hands and feet, according to a study performed at St. Joseph's Healthcare/McMaster University in Hamilton, Canada. view more (2009-04-24)
How much is the world spending on neglected disease research and development? The first comprehensive survey of global spending on neglected disease R&D, published in this week's PLoS Medicine, finds that just over $US 2.5 billion was invested into R&D of new products in 2007, with three diseases-HIV/AIDS, TB, and malaria-receiving nearly 80% of the total. view more (2009-02-04)
Stress tests to confirm need for cardiac stent not occurring in most patients, new study finds UCSF researchers investigating the appropriate use of procedures to open narrowed coronary arteries -- such as angioplasty and stenting -- found that less than half of Medicare patients had documented noninvasive stress testing prior to elective percutaneous coronary intervention, or PCI, the clinical name for such procedures. view more (2008-10-15)
No justification for denying obese patients knee replacements There is no justification for denying obese patients knee replacement surgery: They benefit almost as much as anyone else from the procedure, concludes a small study published ahead of print in the Annals of the Rheumatic Diseases. view more (2008-07-24)
New Guidelines for Treating Rheumatoid Arthritis Proven combinations of medicines and the introduction of new anti-arthritis drugs have significantly improved the treatment of rheumatoid arthritis (RA), according to guidelines issued by the American College of Rheumatology and co-authored by physicians at the University of Alabama at Birmingham (UAB). view more (2008-07-23)
Heavy birthweight babies twice as likely to develop rheumatoid arthritis Heavy birthweight female babies are twice as likely to develop rheumatoid arthritis in adulthood as their average birthweight peers, suggests research published ahead of print in the Annals of the Rheumatic Diseases. view more (2008-06-30)
Heavy birthweight increases risk of developing rheumatoid arthritis People who have a birthweight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birthweight. view more (2008-06-30)
Early life infections increase the risk of rheumatoid arthritis and juvenile idiopathic arthritis Infections during the first year of life are a marker of increased risk of developing specific types of arthritis later in life. view more (2008-06-16)
Novel DNA microarray chip predicts functional impairment and remission in rheumatoid arthritis A new DNA microarray chip can predict severe disability and remission in patients with rheumatoid arthritis (RA), as presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France. The chip (called the 'ARTchip') has yielded two clinical-genetic models of RA outcomes, to assist physicians in... view more... (2008-06-16)
Rheumatoid arthritis factors equal to cardiovascular factors in risk of severe cardiovascular events Certain cardiovascular disease (CVD) risk factors and rheumatoid arthritis (RA) disease factors have a similar effect on an RA patient's risk of experiencing myocardial infarction (MI) or stroke. view more (2008-06-16)
CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients should undergo compulsory cardiovascular (CV) risk management and existing CV risk calculators should be adapted to the increased CV risk in inflammatory rheumatic disease patients. view more (2008-06-16)
Hand bone mineral density is an effective predictor of mortality in rheumatoid arthritis Low bone mineral density in the hand is a valid predictor of overall mortality in patients with rheumatoid arthritis (RA) and indicates long-term prognosis, according to a new study presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France. Digital X-ray radiogrammetry (DXR) demonstrated bone... view more... (2008-06-13)
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