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Conaway Lab Identifies Novel Mechanism for Regulation of Gene Expression
The Stowers Institute's Conaway Lab has demonstrated that an enzyme called Uch37 is kept in check when it is part of a human chromatin remodeling complex, INO80. The results were published in today's issue of Molecular Cell.    view more (2008-09-29)

Older adults can take medicines more safely and effectively by charting their daily routines
Older adults may be better able to comply with medication regimens by working with providers to fill out simple paper tables that track what they take and when they take it.   view more (2008-09-10)

Characterization of grapevine transposons furthers understanding of in vino variety
The grapevine (Vitis vinifera) is a widely cultivated crop that has been subjected to intensive breeding since the Neolithic period (from ~10,500 to ~6,000 years ago). The domestication of grapevine has undergone a selection for traits important for its cultivation and usage.   view more (2008-09-03)

Rice lab finds molecular clues to Wilson disease
Using a combination of computer simulations and cutting-edge lab experiments, physical biochemists at Rice University have discovered how a small genetic mutation -- which is known to cause Wilson disease -- subtly changes the structure of a large, complex protein that the body uses to keep copper... view more (2008-08-20)

Bacteria reveal secret of adaptation at Evolution Canyon
Bacteria living on opposite sides of a canyon have evolved to cope with different temperatures by altering the make-up of their 'skin', or cell membranes. Scientists have found that bacteria change these complex and important structures to adapt to different temperatures by looking at the... view more (2008-07-28)

Complex questions asked by defense lawyers linked to convictions in child abuse trials
Defendants in child abuse cases are more likely to be convicted if their defense lawyer uses complicated language when interrogating young victims according to new research out of the University of Toronto and the University of Southern California.   view more (2008-07-21)

Novel hydrogel systems for dentin regeneration
Dental caries, or tooth decay, continues to be the most prevalent infectious disease in the world, presenting significant public health challenges and socio-economic consequences.   view more (2008-07-07)

Crossed (Evolutionary) Signals?
What do humans and single-celled choanoflagellates have in common? More than you'd think. New research into the choanoflagellate genome shows these ancient organisms have similar levels of proteins that cells in more complex organisms, including humans, use to communicate with each other.   view more (2008-07-02)

Estimation of isolation times in the Drosophila simulans complex
The Drosophila simulans species complex continues to serve as an important model system for the study of new species formation. The complex is comprised of the cosmopolitan species, D. simulans, and two island endemics, D. mauritiana and D. sechellia.   view more (2008-06-26)

Binge drinking due to 'copying' behavior
THE rise in binge drinking in the young is a "fashion phenomenon" where drinkers are copying their associates' behaviour, new research has shown.   view more (2008-06-25)

Understanding the migration of cancer cells
Lamellipodia are veil-shaped protrusions of the plasma membrane, that can turn into upward-curled ruffles if they fail to adhere to the substrate.   view more (2008-06-23)

Diamonds Are Forever Revealing New Insights into Earth's Development
Diamonds will take center stage this month in countless wedding ceremonies and other celebrations. In addition to their usual role as symbols of enduring love and fidelity, diamonds are now also helping geologists unravel clues about how the earth's precious metal mineralization was formed and why... view more (2008-06-13)

Researchers reveal insights into hidden world of protein folding
The proteins upon which life depends share an attribute with paper airplanes: Unless folded properly, they just won't fly.   view more (2008-06-12)

At the synapse: Gene may shed light on neurological disorders
In our brains, where millions of signals move across a network of neurons like runners in a relay race, all the critical baton passes take place at synapses.   view more (2008-05-23)

Novel enzyme inhibitor paves way for new cancer drug
Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development.   view more (2008-05-16)

Researchers discover architecture for fundamental processes of life
A team of Canadian researchers has completed a massive survey of the network of protein complexes that orchestrate the fundamental processes of life.   view more (2008-05-14)

Model successfully predicts large river system fish diversity
While scientists have developed methods to predict aspects of fish diversity in specific river locations, a model to understand what factors may drive a comprehensive suite of fish biodiversity patterns in a large and complex system of rivers has been elusive.   view more (2008-05-09)

Is there anybody out there?
Is there anybody out there? Probably not, according to a scientist from the University of East Anglia. A mathematical model produced by Prof Andrew Watson suggests that the odds of finding new life on other Earth-like planets are low, given the time it has taken for beings such as humans to evolve... view more (2008-04-17)

Argonne scientists develop techniques for creating molecular movies
They may never win an Oscar, but scientists at the U.S. Department of Energy's (DOE) Argonne National Laboratory have developed techniques for creating accurate movies of biological and chemical molecules, a feat only theorized up until now.   view more (2008-04-16)

For children with heart disease, a risk of attention and behavior problems
Schoolchildren who required surgery as infants for congenital heart disease (CHD) run a significant risk of having problems with inattention and hyperactivity, and often require remedial services in school.   view more (2008-04-07)

Researcher discovers pathway plants use to fight back against pathogens
Plants are not only smart, but they also wage a good fight, according to a University of Missouri biochemist. Previous studies have shown that plants can sense attacks by pathogens and activate their defenses.   view more (2008-04-01)

Study questions 'cost of complexity' in evolution
Higher organisms do not have a "cost of complexity" - or slowdown in the evolution of complex traits - according to a report by researchers at Yale and Washington University in Nature.   view more (2008-04-01)

A fly's tiny brain may hold huge human benefits
Before swatting at one of those pesky flies that come out as the days lengthen and the temperature rises, one should probably think twice.   view more (2008-03-25)

First 'rule' of evolution suggests that life is destined to become more complex
In a study published in the Proceedings of the National Academy of Sciences researchers have found evidence which suggests that evolution drives animals to become increasingly more complex.   view more (2008-03-18)

Workman Lab characterizes novel regulator of chromosome function
The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process by which all chromosome functions are controlled.   view more (2008-03-11)

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