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JDRF funded research shows promise for prevention, reversal of type 1 diabetes
Researchers at the University of California, San Francisco have reported that two common cancer drugs have been used to block and reverse type 1 diabetes in mice.   view more (2008-11-19)

Drops in blood oxygen levels may be key to sudden death in some epilepsy patients
A new study by researchers at UC Davis Medical Center suggests that the sudden unexplained deaths of some epilepsy patients may be a result of their brains not telling their bodies to breathe during seizures.   view more (2008-11-18)

New molecular insight into vertebrate brain development
In the December 1st issue of G&D, Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors - and potential therapeutic targets - that may be involved in... view more (2008-11-18)

Biomedical engineers' detective work reveals antibiotic mechanism
A series of genetic clues led a team of Boston University biomedical engineers to uncover exactly how certain antibiotics kill bacteria. The findings could help rejuvenate the efficacy of older antibiotics and reveal new antibiotic targets within bacterial cells.   view more (2008-11-18)

The bonsai effect: Wounded plants make jasmonates, inhibiting cell division, stunting growth
It is well known that plants growing under unfavourable conditions are generally smaller than those growing in stress-free conditions: indeed it is estimated that in the US, abiotic stress reduces the yield of agricultural crops by an average of 22%.   view more (2008-11-12)

Case Western Reserve University uncovers genetic basis for some birth defects
A multidisciplinary research team at Case Western Reserve University led by Gary Landreth, Ph.D., a professor in the School of Medicine's Department of Neurosciences, has uncovered a common genetic pathway for a number of birth defects that affect the development of the heart and head. Abnormal... view more (2008-11-11)

Stanford research sheds light on key trigger of embryonic stem cell differentiation
Clusters of mouse embryonic stem cells called embryoid bodies more closely approximate true embryos in organization and structure than previously thought, according to researchers at the Stanford University School of Medicine. Harnessing the signals that influence the cells' fate may help... view more (2008-11-06)

Apelin hormone injections powerfully lower blood sugar
By injecting a hormone produced by fat and other tissues into mice, researchers report in the November Cell Metabolism that they significantly lowered blood sugar levels in normal and obese mice.   view more (2008-11-05)

A new weapon in the fight against obesity and diabetes
A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues.   view more (2008-11-05)

Apelin to rescue diabetics
Sugar is naturally present in the blood in the form of glucose and is stored in the liver or adipose tissue (fat) thanks to the action of insulin. Glucose is stored or directly used to ensure satisfactory function of the heart, brain and so on according to the body's demands.   view more (2008-11-05)

New therapeutic target identified for rheumatoid arthritis
Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis.   view more (2008-11-05)

What's the role of beta-catenin in colorectal cancers?
Beta-catenin, a central molecule of the Wnt-signaling pathway was previously known to involve in the tumorigenesis of various gastrointestinal cancers such as gastric cancer and colon cancer.   view more (2008-11-03)

Predatory bacterial swarm uses rippling motion to reach prey
Like something from a horror movie, the swarm of bacteria ripples purposefully toward their prey, devours it and moves on.   view more (2008-10-30)

NJIT professor finds engineering technique to identify disease-causing genes
Scientists believe that complex diseases such as schizophrenia, major depression and cancer are not caused by one, but a multitude of dysfunctional genes.   view more (2008-10-29)

Mechanism in cells that generate malignant brain tumors may offer target for gene therapy
Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development of these cells from which malignant brain tumors may originate.   view more (2008-10-27)

Study may explain exercise-induced fatigue in muscular dystrophies
A University of Iowa study suggests that the prolonged fatigue after mild exercise that occurs in people with many forms of muscular dystrophy is distinct from the inherent muscle weakness caused by the disease.   view more (2008-10-27)

Building the blood-brain barrier
Construction of the brain's border fence is supervised by Wnt/b-catenin signaling, report Liebner et al. in The Journal of Cell Biology.    view more (2008-10-27)

Female Plant 'Communicates' Rejection or Acceptance of Male
Without eyes or ears, plants must rely on the interaction of molecules to determine appropriate mating partners and avoid inbreeding.   view more (2008-10-24)

Research uncovers new steps on pathway to enlarged heart
Researchers have new insight into the mechanisms that underlie a pathological increase in the size of the heart. The research, published by Cell Press in the October 24th issue of the journal Molecular Cell, may lead to the development of new strategies for managing this extremely common cardiac... view more (2008-10-24)

Silencing a protein could kill T-Cells, reverse leukemia
Blocking the signals from a protein that activates cells in the immune system could help kill cells that cause a rare form of blood cancer, according to physicists and oncologists who combined computer modeling and molecular biology in their discovery.   view more (2008-10-23)

Mediator in communication between neurons and muscle cells found
A missing piece of the puzzle of how neurons and muscle cells establish lifelong communication has been found by researchers who suspect this piece may be mutated and/or attacked in muscular dystrophy.   view more (2008-10-23)

A new relationship between brain derived neurotrophic factor and inflammatory signaling
In the October 14th edition of Science Signaling researchers at Boston University School of Medicine (BUSM), The Children's Hospital of Philadelphia/University of Pennsylvania School of Medicine and The University of Colorado Denver School of Medicine have shown that the development of epilepsy in... view more (2008-10-23)

MIT: Computer model reveals cells' inner workings
After spending years developing a computational model to help illuminate cell signaling pathways, a team of MIT researchers decided to see what would happen if they "broke" the model.   view more (2008-10-17)

Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al.   view more (2008-10-14)

Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al.   view more (2008-10-13)
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