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Making flies sick reveals new role for growth factors in immunity
A Salmonella infection is not a positive experience. However, by infecting the common laboratory fruit fly Drosophila melanogaster with a Salmonella strain known for causing humans intestinal grief, researchers in the School of Life Sciences at Arizona State University have shed light on some key... view more (2008-10-27)

Mechanism in cells that generate malignant brain tumors may offer target for gene therapy
Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development of these cells from which malignant brain tumors may originate.   view more (2008-10-27)

Study may explain exercise-induced fatigue in muscular dystrophies
A University of Iowa study suggests that the prolonged fatigue after mild exercise that occurs in people with many forms of muscular dystrophy is distinct from the inherent muscle weakness caused by the disease.   view more (2008-10-27)

Building the blood-brain barrier
Construction of the brain's border fence is supervised by Wnt/b-catenin signaling, report Liebner et al. in The Journal of Cell Biology.    view more (2008-10-27)

Female Plant 'Communicates' Rejection or Acceptance of Male
Without eyes or ears, plants must rely on the interaction of molecules to determine appropriate mating partners and avoid inbreeding.   view more (2008-10-24)

Research uncovers new steps on pathway to enlarged heart
Researchers have new insight into the mechanisms that underlie a pathological increase in the size of the heart. The research, published by Cell Press in the October 24th issue of the journal Molecular Cell, may lead to the development of new strategies for managing this extremely common cardiac... view more (2008-10-24)

Silencing a protein could kill T-Cells, reverse leukemia
Blocking the signals from a protein that activates cells in the immune system could help kill cells that cause a rare form of blood cancer, according to physicists and oncologists who combined computer modeling and molecular biology in their discovery.   view more (2008-10-23)

Mediator in communication between neurons and muscle cells found
A missing piece of the puzzle of how neurons and muscle cells establish lifelong communication has been found by researchers who suspect this piece may be mutated and/or attacked in muscular dystrophy.   view more (2008-10-23)

A new relationship between brain derived neurotrophic factor and inflammatory signaling
In the October 14th edition of Science Signaling researchers at Boston University School of Medicine (BUSM), The Children's Hospital of Philadelphia/University of Pennsylvania School of Medicine and The University of Colorado Denver School of Medicine have shown that the development of epilepsy in... view more (2008-10-23)

MIT: Computer model reveals cells' inner workings
After spending years developing a computational model to help illuminate cell signaling pathways, a team of MIT researchers decided to see what would happen if they "broke" the model.   view more (2008-10-17)

Resveratrol prevents fat accumulation in livers of 'alcoholic' mice
The accumulation of fat in the liver as a result of chronic alcohol consumption could be prevented by consuming resveratrol, according to a new study with mice.   view more (2008-10-15)

Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al.   view more (2008-10-14)

Response to immune protein determines pathology of multiple sclerosis
New research may help reveal why different parts of the brain can come under attack in patients with multiple sclerosis (MS). According to a new study in mice with an MS-like disease, the brain's response to a protein produced by invading T cells dictates whether it's the spinal cord or cerebellum... view more (2008-10-14)

Researchers write protein nanoarrays using a fountain pen and electric fields
Nanotechnology offers unique opportunities to advance the life sciences by facilitating the delivery, manipulation and observation of biological materials with unprecedented resolution.   view more (2008-10-14)

Caltech biologists spy on the secret inner life of a cell
The transportation of antibodies from a mother to her newborn child is vital for the development of that child's nascent immune system.   view more (2008-10-13)

Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al.   view more (2008-10-13)

Hodgkin lymphoma -- new characteristics discovered
Researchers are still discovering new characteristics of Hodgkin lymphoma, a common form of cancer of the lymphatic system. The malignant cells are derived from white blood cells (B cells), but have lost a considerable part of the B cell-specific gene expression pattern.    view more (2008-10-09)

Proteins in sperm unlock understanding of male infertility says new study
Proteins found in sperm are central to understanding male infertility and could be used to determine new diagnostic methods and fertility treatments according to a paper published by the journal Molecular and Cellular Proteomics (MCP).   view more (2008-10-09)

Protein shown to play a key role in normal development of nervous system
A protein that enables nerve cells to communicate with each other plays a key role in controlling the developing nervous system.   view more (2008-10-08)

Rong Li Lab probes mechanism of asymmetry in meiotic cell division
The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes can recruit to their vicinity a protein called formin-2.   view more (2008-10-08)

Burnham Researchers Turn Cancer Friend into Cancer Foe
Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer.   view more (2008-10-08)

Egg whites solve the 3-D problem
The real world is three-dimensional. That's true even in the laboratory, where scientists have to grow cells to study how they develop and what happens when their growth is abnormal.   view more (2008-10-08)

Early-stage gene transcription creates access to DNA
A gene contained in laboratory yeast has helped an international team of researchers uncover new findings about the process by which protein molecules bind to control sequences in genes in order to initiate gene expression, according to findings reported in the journal Nature.   view more (2008-10-07)

MU Researchers Identify Proteins that Play Important Role in Blood Vessel Dysfunction in Type 2 Diabetes
According to the American Heart Association, three-fourths of people with diabetes die of some form of heart or blood-vessel disease.   view more (2008-10-07)

Discovery of natural compounds that could slow blood vessel growth
Using computer models and live cell experiments, biomedical engineers at the Johns Hopkins University School of Medicine have discovered more than 100 human protein fragments that can slow or stop the growth of cells that make up new blood vessels.   view more (2008-10-06)
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