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Researchers discover brain tumor's 'grow-or-go' switch
Cancer cells in rapidly growing brain tumors must adjust to periods of low energy or die. When energy levels are high, tumor cells grow and proliferate. When levels are low, the cells grow less and migrate more. view more (2010-03-12)
Spotlight on rare tumors in hunt for new cancer treatments
New breakthrough treatments for the most common cancers could soon come from cutting-edge research into some of the world's rarest tumors. view more (2010-03-09)
High weight associated with risk of colorectal tumors without microsatellite instability
The increased risk of colorectal cancer associated with obesity may be largely restricted to tumors that have no or low microsatellite instability (MSI), a common condition in most colorectal cancers, according to a new study published online March 8 in the Journal of the National Cancer Institute. view more (2010-03-08)
Possible vaccine for mesothelioma proven safe
Researchers have demonstrated the safety of a potential vaccine against mesothelioma, a rare cancer associated primarily with asbestos exposure. view more (2010-03-04)
New subtype of breast cancer responds to targeted drug
A newly identified cancer biomarker could define a new subtype of breast cancer as well as offer a potential way to treat it, say researchers at Washington University School of Medicine in St. Louis. view more (2010-03-02)
New cancer-fighting strategy focuses on signaling molecules
Cancer researchers studying the immune system have identified a previously unrecognized set of targets and biomarkers to battle solid tumors. view more (2010-02-25)
Arsenic exposure activates an oncogenic signaling pathway; leads to increased cancer risk
Researchers have found a new oncogenic signaling pathway by which the environmental toxin arsenic may lead to adverse health effects, including bladder cancer. view more (2010-02-24)
Mayo oral cancer study shows full tumor genome
Mayo Clinic researchers along with collaborators from Life Technologies are reporting on the application of a new approach for sequencing RNA to study cancer tumors. view more (2010-02-24)
Mayo Clinic Researchers Find Oncogene is Important in Pancreatic Cancer Growth and Spread
Researchers at the Mayo Clinic campus in Florida have found that PKC-iota (PKCi), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKCi in laboratory animals led to a significant decrease in pancreatic tumor growth and spread. view more (2010-02-24)
New tool illuminates connections between stem cells and cancer
Researchers have a new tool to understand how cancers grow -- and with it a new opportunity to identify novel cancer drugs. They've been able to break apart human prostate tissue, extract the stem cells in that tissue, and alter those cells genetically so that they spur cancer. view more (2010-02-22)
VARI Findings May Help Patients with Deadly Kidney Cancer
Van Andel Research Institute (VARI) researchers have found a way to reverse resistance to sunitinib, a treatment that is currently the first line of defense against clear cell renal cell carcinoma (ccRCC), a deadly form of kidney cancer. view more (2010-02-19)
Drug for advanced kidney cancer shrinks tumors prior to surgery
More than 57,000 Americans face a diagnosis of kidney cancer each year. Now patients with advanced disease may soon have another treatment option. view more (2010-02-18)
Fluorescent probes light up cancerous tumors
Building on his Nobel Prize-winning work creating fluorescent proteins that light up the inner workings of cells, a team of researchers led by Howard Hughes Medical Institute investigator Roger Tsien, PhD, professor of pharmacology, chemistry and biochemistry at the University of California, San Diego and the Moores UCSD Cancer Center has... view more... (2010-02-17)
Tobacco use linked to worse outcomes in HPV-positive head and neck cancer, U-M study finds
Patients with head and neck cancer linked to high risk human papillomavirus, or HPV, have worse outcomes if they are current or former tobacco users, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. view more (2010-02-16)
Researchers create drug to keep tumor growth switched off
A novel - and rapid - anti-cancer drug development strategy has resulted in a new drug that stops kidney and pancreatic tumors from growing in mice. view more (2010-02-12)
Molecular pathways linked to sex, age affect outcomes in lung cancer
The biology of lung cancer differs from one patient to the next, depending on age and sex, according to scientists at Duke University Medical Center. The findings may help explain why certain groups of patients do better than others, even though they appear to have the same disease. view more (2010-02-10)
Clinical course of subepithelial lesions
Although several studies pertaining to the natural history of subepithelial tumors have been published, they have been limited by small sample size and relatively short follow-up. view more (2010-02-05)
New paper describes important advance in imaging of cell death
For quite some time, the "Holy Grail" in medical imaging has been the development of an effective method to image cell death as a means to intervene early in diseases and rapidly determine the effectiveness of treatments. view more (2010-02-01)
Scientists show how molecular switch helps pancreatic cancer beat drugs
Researchers at the Moores Cancer Center at the University of California, San Diego, have found one reason that pancreatic cancer tumors are so difficult to treat with drugs. view more (2010-01-29)
Disarming specialized stem cells might combat deadly ovarian cancer
Eliminating cancer stem cells (CSCs) within a tumor could hold the key to successful treatments for ovarian cancer, which has been notoriously difficult to detect and treat, according to new findings published this week in the journal Oncogene by Yale School of Medicine researchers. view more (2010-01-28)
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