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Largest gene study of childhood IBD identifies 5 new genes
In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease. view more (2009-11-16)
M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers
Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers. view more (2009-10-27)
Probiotic Found to Be Effective Treatment for Colitis In Mice
The probiotic, Bacillus polyfermenticus, can help mice recover from colitis, a new study has found. view more (2009-10-26)
The bowels of infection
Current research suggests that latent cytomegalovirus (CMV) infection may exacerbate inflammatory bowel disease (IBD). The related report by Onyeagocha et al, "Latent cytomegalovirus infection exacerbates experimental colitis," appears in the November 2009 issue of The American Journal of Pathology. view more (2009-10-21)
Discovery of genetic defect may lead to better treatments for common gut diseases
New findings related to an uncommon genetic disorder may impact the diagnosis and treatment of inflammatory bowel disease (IBD), the most common chronic gastrointestinal illness in children and teens. Two million Americans have IBD which involves inflammation of the gastrointestinal tract. view more (2009-10-09)
Oxidized form of a common vitamin may bring relief for ulcerative colitis
New research published in the Journal of Leukocyte Biology finds retinoic acid may alleviate ulcerative colitis and similar irritable bowel diseases. view more (2009-10-01)
Making bacteria make useful proteins
By adapting a single protein on the surface of the bacterium Caulobacter crescentus, researchers at the University of British Columbia have turned it into a protein production factory, making useful proteins that can act as vaccines and drugs. view more (2009-09-08)
Promising new target emerges for autoimmune diseases
University of Michigan scientists say they have uncovered a fundamentally new mechanism that holds in check aggressive immune cells that can attack the body's own cells. view more (2009-09-02)
Subclinical markers predict relapse in juvenile idiopathic arthritis post methotrexate withdrawal
Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status. view more (2009-06-11)
Electronic Pill Shows Its Smarts by Measuring pH Levels in Digestive Tract
An electronic diagnostic tool called the SmartPill is swallowed by patients in order to take measurements as it travels through the gastrointestinal tract. view more (2009-06-04)
Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine
Researchers at Penn State College of Medicine, working with biochemists, geneticists and clinicians at the University of Bern, Switzerland and in the United Kingdom, have discovered an enzyme that has a key role in inflammatory bowel disease (IBD). view more (2009-06-03)
Newly discovered reactions from an old drug may lead to new antibiotics
A mineral found at health food stores could be the key to developing a new line of antibiotics for bacteria that commonly cause diarrhea, tooth decay and, in some severe cases, death. view more (2009-06-02)
UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage
UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders. view more (2009-06-01)
Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?
Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by caffeic acid, an anti-inflammatory antioxidant compound widely distributed in foods. view more (2009-05-27)
Chronic diarrhea unresponsive to conventional medication: Are you taking lansoprazole?
Lansoprazole is a proton pump inhibitor which powerfully suppresses gastric acid production and is widely prescribed for chronic use in gastroesophageal reflux disease. view more (2009-05-14)
Helping Hand of Hybrid Surgery Benefits Colorectal Patients
Despite rapid strides in minimally invasive surgical techniques -- most notably, laparoscopy -- traditional open surgery remains the most common surgical option across the United States for people with diseases of the rectum and colon. view more (2009-04-16)
What makes C-Diff superbug deadly?
A major breakthrough about the potentially deadly superbug Clostridium difficile (C-diff) could lead to new ways to combat the bacterium, according to a study to be published March 1 in the journal Nature. view more (2009-03-02)
Scientists at Scripps Research identify a mutation that causes inflammatory bowel disease
A team of scientists at The Scripps Research Institute has linked a mouse mutation to an increased susceptibility for developing inflammatory bowel disease -- represented in humans as Crohn's disease and ulcerative colitis, which together are estimated to affect more than a million people in the United States. view more (2009-02-11)
Children with inflammatory bowel disease have surprisingly high folate levels, study finds
Children with newly diagnosed cases of inflammatory bowel disease have higher concentrations of folate in their blood than individuals without IBD, according to a new study led by researchers at the University of California, San Francisco and UC Berkeley. view more (2009-01-26)
Unexpected finding opens up new way to stop autoimmune diseases and transplant rejection
After several years of battling recurring infections, the last thing a patient and her doctors ever expected was that the cause of her problems might actually help millions live longer, more active lives. view more (2009-01-23)
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