A-beta Production Current Events | A-beta Production News
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Is transforming growth factor-beta involved in intestinal wound healing?
Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease. Transforming growth factor- beta (TGF- beta) is involved in the regulation of cell migration, cell differentiation, extracellular matrix deposition, and immune responses. view more (2009-03-31)
Researchers discover mechanism of insulin production that can lead to better treatment for diabetes
How a specific gene within the pancreas affects secretion of insulin has been discovered by researchers from the Hebrew University of Jerusalem, in collaboration with Japanese and American universities. view more (2009-11-13)
Amyloid beta protein gets bum rap
While too much amyloid beta protein in the brain is linked to the development of Alzheimer's disease, not enough of the protein in healthy brains can cause learning problems and forgetfulness, Saint Louis University scientists have found. view more (2009-11-10)
Anesthesia and Alzheimer's
In studies of human brain cells, the widely-used anesthetic desflurane does not contribute to increased production of amyloid-beta protein; however, when combined with low oxygen conditions, it can produce more of this Alzheimer's associated protein. view more (2008-04-28)
New target for heart failure therapy identified
A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers. view more (2009-03-17)
T-beta-RIII joins the fight against breast cancer
Although the soluble factor TGF-beta has been shown to suppress the growth of tumor cells in the early stages of breast cancer, high levels of TGF-beta during the later stages of the disease are associated with a poor outcome. view more (2006-12-08)
Test quickly assesses whether Alzheimer's drugs are hitting their target
A test developed by physician-scientists at Washington University School of Medicine in St. Louis may help assess more quickly the ability of Alzheimer's drugs to affect one of the possible underlying causes of Alzheimer's disease in humans, accelerating the development of new treatments. view more (2009-04-10)
Human beta cells can be easily induced to replicate, according to study in Diabetes
Researchers at the University of Pittsburgh School of Medicine have successfully induced human insulin-producing cells, known as beta cells, to replicate robustly in a living animal, as well as in the lab. view more (2009-01-14)
Researchers close in on origins of main ingredient of Alzheimer's plaques
The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned. view more (2008-04-10)
Anticancer drugs might be of benefit to sickle-cell patients
Sickle cell disease (SCD) is an inherited blood disorder caused by a genetic mutation that leads to the generation of a mutant form of the beta-globin chain of hemoglobin (Hb). view more (2007-12-07)
High-dose Interferon Beta-1B On Alternate Days Could Offer Increased Clinical Benefit For People With Multiple Sclerosis (p 1453)
A study published in this week's issue of THE LANCET suggests that high-dose interferon beta-1b administered every other day is more effective than interferon beta-1a once a week for people with multiple sclerosis (MS). There are three interferon beta therapies known to be effective in reducing MS symptoms: interferon beta-1a 30 mcg administered... view more... (2002-04-24)
UCSD Research May Lead to Targeted Treatment for Asthma Sufferers
The bronchial tubes of a patient with severe asthma can become scarred due to repeated episodes of allergic inflammation in the airways. The scarring results in blocked airways, excessive production of mucus, and shortness of breath. view more (2005-11-29)
Tumors stopped from spreading to new sites
For several types of cancer, persistently high levels of the soluble factor TGF-beta in the blood after surgery, chemotherapy, or radiation therapy correlate with increased risk of early metastasis and a poor prognosis. view more (2007-04-06)
A Novel Strategy for Combating Aids-Related Fungal Infections
Research at the Sir William Dunn School of Pathology has identified Dectin-1 as the beta-glucan receptor on immune cells. This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of Dectin-1 as the beta-glucan receptor may also provide... view more... (2004-10-08)
Government money for multiple sclerosis patients could be better spent
The National Institute for Clinical Excellence (NICE) has announced that neither interferon beta nor glatiramer can be recommended for multiple sclerosis in the NHS. However, the UK government plans to make these drugs available through a risk sharing scheme, despite limited evidence of clinical and cost effectiveness. Researchers in this week's... view more... (2003-02-12)
Detection Of Antibodies Could Identify MS Patients Who Do Not Respond Well To Interferon Beta (P1184)
Danish research published in this week's issue of THE LANCET highlights how the detection of antibodies to interferon beta-the first choice treatment for multiple sclerosis patients-could be important in identifying patients who do not respond well to interferon beta, with implications for the provision of alternative drug therapy. Interferon beta... view more... (2003-10-08)
Mayo Clinic researchers find agents that speed up destruction of proteins linked to Alzheimer's
Taking a new approach to the treatment and prevention of Alzheimer's disease, a research team led by investigators at the Mayo Clinic campus in Florida has shown that druglike compounds can speed up destruction of the amyloid beta (A-beta) proteins that form plaque in the brains of patients with the disorder. view more (2009-04-22)
HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress... view more... (2009-03-26)
Anaemia Treatment Could Worsen Cancer Prognosis (p1255)
Results of a European study in this week's issue of THE LANCET cast doubt over the value of treating anaemia with erythropoietin (epoetin beta) among patients who have cancer. Results of the study show that anaemic patients fare better in terms of reduced cancer progression and increased survival if their anaemia is not treated around the time of... view more... (2003-10-15)
Alzheimer's study first to explain death of brain cells
Researchers at Children's Hospital & Research Center at Oakland (CHRCO) have published a new study that is the first to explain how brain cells die in patients with Alzheimer's Disease. view more (2006-03-15)
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