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Stem cells found in adult hair follicles may provide alternative to embryonic stem cells
Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a... view more (2006-12-12)

Mutation in brain cells of descendants of Abraham Lincoln suggest he suffered from movement disorder
Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum- the part of the brain... view more (2006-02-03)

A clue to core problem of neurodegenerative disease and cell death
Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.   view more (2006-02-10)

A Theoretical Breakthrough Inspired by Experiment-Calculating Electron Correlations in the Hydrogen Molecule
Need to understand the details of how a molecule is put together? Want to see the effects of the intricate dance that its electrons do to make a chemical bond? Try blowing a molecule to bits and calculating what happens to all the pieces.   view more (2005-12-16)

High polyunsaturated fat and vitamin E intake may halve motor neurone disease risk
A high dietary intake of polyunsaturated fat and vitamin E seems to halve the risk of developing motor neurone disease, suggests research published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry.   view more (2006-04-27)

Study finds a high caloric diet may prevent the progression of amyotrophic lateral sclerosis
A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS).   view more (2006-04-18)

Cyanobacteria ("blue-green algae") produce toxin with possible connection to neurodegerative disorders
It is well known that a tiny number of cyanobacteria, previously known as blue-green algae, produce substances that can be toxic to both humans and animals. Now a research team from Sweden, Scotland, and the U.S. has found that a further toxin (BMAA, -methyl amino-alanine) with a possible... view more (2005-04-08)

Changes in brain density can help predict schizophrenia
Changes in brain density could be used to predict whether an individual who is at risk for schizophrenia is likely to develop the condition or not.   view more (2006-12-07)

Brain-computer link allows paralyzed patient to manipulate devices by thought
A patient with a spinal cord injury was able to produce brain signals associated with intending to move his paralyzed limbs, signals picked up by an implanted sensor and translated into electronic impulses that allowed him to control a computer cursor and manipulate mechanical devices.   view more (2006-07-13)

Protein aggregates in Lou Gehrig's disease linked to neuron death
French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis (ALS) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure   view more (2005-10-27)

Human stem cells delay start of Lou Gehrig's disease in rats
Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life.   view more (2006-10-16)

Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's
Researchers at the Burnham Institute for Medical Research have discovered a mechanistic link between cellular stress caused by free radicals and accumulation of misfolded proteins that lead to nerve cell injury and death in neurodegenerative disorders such as Alzheimer's and Parkinson's Disease.   view more (2006-05-25)

UCSF study points to link to neurodegenerative disease target
The findings are relevant for ongoing research in identifying causes and developing treatments for neuromuscular neurodegenerative diseases in humans, such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.   view more (2005-09-02)

Curtain May be Closing on Scientific Water Controversy
The curtain may be ringing down on a scientific controversy regarding the structure of water which arose two years ago.   view more (2006-06-28)

Majority of ALS patients are not depressed
Contrary to what you might think, most people with amyotrophic lateral sclerosis (ALS) are not depressed. They are also not more likely to get depressed as the end of life approaches, and they are not more likely to be depressed if they want to die or hasten their own death.   view more (2005-07-12)

First diagnostic indicator for Amytrophic Lateral Sclerosis (ALS) identified
Claire Collier went to see her doctor shortly after she started experiencing cramping and other symptoms. This started a series of referrals and seemingly endless stream of tests.   view more (2006-02-23)

Mechanism identified for promising neurological drug
Researchers at the San Francisco VA Medical Center have identified the mechanism by which minocycline, a medication currently being studied for the treatment of neurodegenerative diseases including Parkinson's disease and Huntington's disease, protects brain and nerve cells from damage.   view more (2006-06-22)

Neurons grown from embryonic stem cells restore function in paralyzed rats
For the first time, researchers have enticed transplants of embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore function in paralyzed animals.   view more (2006-06-21)

Updated rates of common US neurological disorders
In an up-to-date review of most of the common neurological disorders in the United States published in the January 30, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology, researchers reviewed studies from nearly 500 articles published between 1990 and 2005 to... view more (2007-01-30)

Cognitive impairment appears to be common in ALS patients
In a study of 40 patients with amyotrophic lateral sclerosis (ALS), about one-third showed evidence of cognitive impairment, but these deficits did not appear to be related to survival.   view more (2006-03-14)

Variations in detoxifying genes linked to Lou Gehrig's disease
Genetic variations in three enzymes that detoxify insecticides and nerve gas agents as well as metabolize cholesterol-lowering statin drugs may be a risk factor for developing sporadic amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease), and possibly responsible for a reported twofold... view more (2006-07-06)

Promising therapy for ALS delivers antisense drug directly to nervous system
Researchers from the University of California, San Diego (UCSD) School of Medicine, the Center for Neurologic Study and Isis Pharmaceutical Corporation have designed and tested a molecular therapy in animals that they hope will be a major development in the fight to treat amyotrophic lateral... view more (2006-07-27)

Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.   view more (2006-06-09)

First Direct Observations of Spinons and Holons
Working at the Advanced Light Source (ALS) of the U.S. Department of Energy's Lawrence Berkeley National Laboratory, a team of researchers has observed the theoretical prediction of electron "spin-charge separation" in a one-dimensional solid.   view more (2006-07-17)

Discovery of agile molecular motors could aid in treating motor neuron diseases
Over the last several months, the labs of Yale Goldman, MD, PhD, Director of the Pennsylvania Muscle Institute at the University of Pennsylvania School of Medicine, and Erika Holzbaur, PhD, Professor of Physiology, have published a group of papers that, taken together, show proteins that function... view more (2006-07-18)
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