Abnormal Aggregates Current Events | Abnormal Aggregates News
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Lessons from yeast: A possible cure for Parkinson's disease?
Parkinson disease (PD) is a debilitating and lethal neurodegenerative disease, for which there is currently no cure. It is caused by the progressive loss of nerve cells that produce the chemical dopamine and is characterized by the accumulation of abnormal aggregates of a protein called alpha-syn in these dopaminergic nerve cells. view more (2008-08-15)
Clumps of red and white blood cells may contribute to sickle cell disease
It's long been known that patients with sickle cell disease have malformed, "sickle-shaped" red blood cells - which are normally disc-shaped - that can cause sudden painful episodes when they block small blood vessels. view more (2008-04-29)
Proteasome activator enhances survival of Huntington's disease neuronal model cells
To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins. view more (2007-02-28)
Protein aggregates in Lou Gehrig's disease linked to neuron death
French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis (ALS) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure view more (2005-10-27)
Is endotoxin receptor CD14 rs2569190/C-159T gene correlated with chronic hepatitis C?
It is still unknown why the natural history of chronic disease caused by hepatitis C virus (HCV), which currently infects 3% of the world's population, varies from mild in some patients to rapidly progressing in others. view more (2009-08-27)
Yeast model shows promise as Alzheimer's test
A century ago this month, German psychiatrist Alois Alzheimer formally described characteristics of the neurodegenerative disease which ultimately came to bear his name. view more (2006-11-20)
NIST trumps the clumps: Making biologic drugs safer
Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals. view more (2008-07-24)
Vaccine thwarts the tangles of Alzheimer's
A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease. view more (2007-08-22)
Preserved in crystal
Scientists at the Weizmann Institute of Science recently discovered a new source of well-preserved ancient DNA in fossil bones. view more (2006-02-03)
Study suggests new treatments for Huntington's disease
Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington's disease causes neurodegeneration. view more (2008-01-10)
Brittle prions are more infectious
Brittleness is often seen as a sign of fragility. But in the case of infectious proteins called prions, brittleness makes for a tougher, more menacing pathogen. view more (2006-06-29)
Red, red wine: How it fights Alzheimer's
Scientists call it the "French paradox" - a society that, despite consuming food high in cholesterol and saturated fats, has long had low death rates from heart disease. view more (2008-11-21)
Barrow researchers identify new brain receptor, possible target for Alzheimer's treatment
Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease. view more (2009-07-17)
Scientists design simple dipstick test for cocaine, other drugs
Researchers at the University of Illinois at Urbana-Champaign have developed a simple "dipstick" test for detecting cocaine and other drugs in saliva, urine or blood serum. view more (2006-11-14)
Many asthmatic patients may have abnormal breathing patterns
Large numbers of asthmatic patients may have abnormal breathing patterns, finds a study in this week's BMJ, suggesting an important unrecognised diagnostic overlap between asthma and dysfunctional breathing. All adults receiving treatment for asthma in one general practice were surveyed to assess symptoms associated with abnormal breathing. About... view more... (2001-05-02)
'WAIT AND SEE' POLICY' SUGGESTED FOR WOMEN WITH ABNORMAL CERVICAL SMEARS IN PRESENCE of HIGH-RISK HUMAN PAPILLOMAVIRUS (p 1782)
Women with abnormal cervical smears (mild to moderate dyskaryosis) and who are positive for the high-risk form of human papillomavirus (HR-HPV) should not be treated for at least 6 months after cytological screening to see if the virus disappears, suggest authors of a research letter in this week's issue of THE LANCET. If viral clearance occurs,... view more... (2001-11-21)
Repair not destruction: A new approach to treating retinopathy
Many diseases of the eye (such as retinopathy of prematurity (ROP) and diabetic retinopathy) that result in loss of vision are the result of the growth of abnormal blood vessels that leak and bleed. view more (2006-11-17)
New research points toward mechanism of age-onset toxicity of Alzheimer's protein
Like most neurodegenerative diseases, Alzheimer's disease usually appears late in life, raising the question of whether it is a disastrous consequence of aging or if the toxic protein aggregates that cause the disease simply take a long time to form. view more (2006-08-11)
Scientists discover age-regulated cellular activities that protect against protein aggregation
Alzheimer's disease now strikes more than one in 30 Americans, and about half the population that lives past 85 acquires Alzheimer's. view more (2006-08-14)
Study links Alzheimer's disease to abnormal cell division
A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it. view more (2006-01-18)
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