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Heart-failure patients benefit from pharmacist care
Heart-failure patients take their medicine more reliably when under the care of a pharmacist, resulting in fewer emergency-room visits and hospital stays as well as lower health-care costs, according to a study from the University of North Carolina at Chapel Hill School of Pharmacy. view more (2007-05-15)
Future therapies for stroke may block cell death
A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University. view more (2007-06-14)
Mutation in renin gene linked to inherited kidney disease
A mutation in a gene that helps regulate high blood pressure is a cause of inherited kidney disease, according to a new study by researchers at Wake Forest University School of Medicine, Charles University in Prague and colleagues. view more (2009-08-19)
Carvedilol shown to have unique characteristics among beta blockers
In a new study, researchers report that a class of heart medications called beta-blockers can have a helpful, or harmful, effect on the heart, depending on their molecular activity. view more (2009-11-23)
Massey researchers induce cell death in leukemia
Researchers from the Virginia Commonwealth University Massey Cancer Center today presented preclinical research at the American Association of Cancer Research's annual meeting suggesting the potential of a new combination treatment for chronic lymphocytic leukemia (CLL). view more (2007-04-17)
Treating hypertension in black people
The latest issue of Effective Health Care summarises the evidence on which drug works best for black people with hypertension. view more (2004-10-15)
Blood pressure drug may have added benefit
University of Kentucky researchers have discovered a possible added benefit of a novel new drug that lowers blood pressure. view more (2008-02-15)
Different anticoagulant regimens yield equal results
Patients with acute coronary syndromes (ACS) receiving early invasive treatment including angiography and percutaneous coronary intervention (PCI) have comparable results at 1 year in terms of mortality and ischemic outcomes no matter which of three different anticoagulant regimens they are on. view more (2007-12-05)
Curacyte scientists discover new anti-tumour agents
Curacyte AG, a Munich-based drug development company focused on novel treatments of inflammatory diseases, thrombotic disorders and cancer has announced today that its scientists have discovered a series of novel small molecule inhibitors of matriptase, a trypsin-like serine protease. Matriptase is an important mediator in the degradation of the... view more... (2003-06-17)
Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells. view more (2006-06-26)
UC Davis researchers shed new light on how chemotherapy-induced leukemia develops
Topoisomerase II inhibitors are among the most successful chemotherapy drugs used to treat human cancer. view more (2005-11-16)
Lancet publishes proactive study: Diabetes treatment reduces risk of heart attacks & strokes
A study published in The Lancet today shows that Takeda's ACTOS® (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication, such as statins, fibrates, ACE inhibitors, beta blockers, other glucose-lowering... view more... (2005-10-10)
Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. view more (2008-04-11)
8 plants from South Africa may hold potential for treating high blood pressure
Medicinal plants are an integral part of African culture, one of the oldest and most diverse in the world. In South Africa, 21st century drug therapy is used side-by-side with traditional African medicines to heal the sick. view more (2007-05-02)
The Definitive Beta-blocker For Heart Failure? (pp 2, 7, 14)
Results of a European study in this week's issue of THE LANCET suggest that the beta-blocker carvedilol offers substantial survival benefit compared with another widely-used beta blocker for the treatment of chronic heart failure. Beta blockers reduce death in patients who are also taking diuretics and ACE inhibitors for chronic heart failure. In... view more... (2003-07-02)
Gentech breakthough for ecological Chrysanthemums
Researchers at Plant Research International in the Netherlands have achieved a breakthrough in the development of chrysanthemums with resistance to thrips, bringing the ecological cultivation of chrysanthemums a step closer. This is the conclusion of the thesis with which Seetharam Annadana, a Plant Research International guest member of staff... view more... (2001-12-13)
Polycystic kidney disease: MRI provides an early alert to progression
A new method using magnetic resonance imaging (MRI) accurately tracks structural changes that predict functional changes earlier than standard blood and urine tests in people with autosomal dominant polycystic kidney disease (PKD). view more (2006-05-18)
Cholinesterase inhibitors reduce aggression, wandering and paranoia in Alzheimer's disease
Cholinesterase inhibitors, used to treat cognitive symptoms of Alzheimer's disease, are also a safe and effective alternative therapy for the behavioral and psychological symptoms of dementia, according to a study that appears in the December 2008 edition of Clinical Interventions in Aging. view more (2008-12-10)
Hormone drug type makes survival difference in advanced breast cancer
Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies. view more (2007-01-31)
Cancer therapy: A role for MAPK inhibitors combined with mTORC1 inhibitors
Nearly a decade ago, while it was being tested as an immunosuppressive agent to prevent organ rejection in transplant patients, the drug rapamycin was also discovered to have anti-tumor properties. Since then, several rapamycin analogs known as mTOR (mammalian target of rapamycin) inhibitors have been tested in clinical trials for the treatment of... view more... (2008-08-22)
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