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Similar outcomes for patients with ACS treated with different anticoagulant regimens
Patients with acute coronary syndromes such as unstable angina who were undergoing an invasive treatment and received one of three anticoagulant regimens did not have significant differences in the rates of ischemia or death after one year. view more (2007-12-05)
Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
UCLA scientists, along with collaborators from Purdue University, have demonstrated that HIV protease inhibitors - crucial drugs for HIV treatment - block a cellular enzyme important for generating the structural scaffolding for the cell nucleus. view more (2007-07-17)
Most NSAIDs raise risk of death after heart attack
Taking either COX-2 inhibitors or other non-steroidal anti-inflammatory drugs (NSAIDs) after a heart attack, especially in high doses, increases the risk of death, researchers reported at the American Heart Association's Scientific Sessions 2005. view more (2005-11-14)
Nicorandil Could Improve Outcome For Angina Patients
Results of a UK study in this week's issue of THE LANCET suggest that the antianginal drug nicorandil could reduce the risk of cardiovascular disease associated with angina. Angina occurs in 10% of men aged older than 60 years in the UK (10-15 years later in women), and is a common underlying cause of coronary heart disease (CHD). Aspirin,... view more... (2002-04-10)
Drug combo may reduce protease inhibitor-related hardening of the arteries
Physiologists may have found a way to decrease the risk of hardening of the arteries that accompanies the long-term use of protease inhibitors, a class of drugs that has emerged as the most effective treatment against HIV and AIDS. view more (2006-09-05)
Older drivers unaware of risks from medications and driving
Most older drivers are unaware of the potential impact on driving performance associated with taking medications, according to new research from the Center for Injury Sciences at the University of Alabama at Birmingham (UAB). view more (2009-08-12)
Tumors stopped from spreading to new sites
For several types of cancer, persistently high levels of the soluble factor TGF-beta in the blood after surgery, chemotherapy, or radiation therapy correlate with increased risk of early metastasis and a poor prognosis. view more (2007-04-06)
Novel approach may protect against heart attack injury
Researchers at The Children's Hospital of Philadelphia have manipulated cell activity that occurs during the interruption of blood flow to strongly protect heart tissue in animal studies. view more (2008-07-11)
Proton pump inhibitors increase risk of heart attacks for patients on common cardiac drug
Patients taking the common cardiac drug clopidogrel following a heart attack are at a significantly higher risk of a recurrence if they are also taking widely used acid-lowering medications called proton pump inhibitors, a new study published online in CMAJ has found (http://www.cmaj.ca/cgi/rapidpdf/cmaj.082001). view more (2009-01-29)
Heart attack prescription drug strategy may save lives and reduce healthcare costs
Full prescription coverage of heart drugs could help heart attack survivors live longer, better lives and lower the nation's healthcare costs, according to a new analysis reported in Circulation: Journal of the American Heart Association. view more (2008-02-19)
ESC Congress 2004: Improvement of treatment for ST-elevation myocardial infarction in diabetics according to guidelines reduced hospital mortality in clinical practice by 36% between 1994 and 2002
Diabetes mellitus increases the risk to develop coronary artery disease by the factor two to four. Cardiovascular complications are the leading causes of morbidity and mortality in patients with diabetes. In randomized controlled trials as well as in prospective registries, diabetics with acute ST-elevation myocardial infarction (STEMI) have been... view more... (2004-08-30)
Study suggests some drug resistance to influenza B medications
Use of certain common antiviral drugs during a recent influenza B epidemic in Japan showed the development of viruses with partial resistance to the drugs, according to a study in the April 4 issue of JAMA. view more (2007-04-04)
Pea and whey in the control of high blood pressure
Hypertension or high blood pressure is a major risk factor for the development of cardiovascular diseases, which are the leading causes of morbidity and mortality in western society. It is estimated that 20% of the world's adult population suffers from hypertension. Recently, some functional foods have received considerable attention for their... view more... (2003-09-17)
'Autoantibodies' may be created in response to bacterial DNA
Autoimmune diseases have long been regarded as illnesses in which the immune system creates autoantibodies to attack the body itself. view more (2009-04-28)
USC researchers develop new drug to target tumor cells and blood vessels
Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors. view more (2009-04-20)
Quality improvement effort pays off in diabetes care
Spending money to improve diabetes care at federally qualified community health centers is a sound investment, according to one of the first studies to examine the clinical and economic impact of quality improvement on diabetes care. view more (2007-05-18)
Abacavir Could Play Important Future Role In Treatment Of Children With HIV-1 (p 733)
Results of the Paediatric European Network for Treatment of AIDS (PENTA) 5 Trial, published in this week's issue of THE LANCET, suggest an important future role for the drug abacavir in the treatment of children with HIV-1. Antiretroviral HIV-1 drug treatment for adults in more-developed countries usually involves combination therapy with two... view more... (2002-02-28)
Therapeutic prospects beyond Vioxx
Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models. view more (2006-04-14)
Meta-analyses of global trials finds in favor of aromatase inhibitors
Two separate meta-analyses of clinical trials from around the world that tested tamoxifen against aromatase inhibitor drugs in postmenopausal women with early breast cancer have each reached the same conclusion: aromatase inhibitors are more effective in preventing breast cancer from coming back. view more (2008-12-12)
Curacyte awarded a EUR1.2M grant to fund development of Factor Xa inhibitors
Curacyte AG, a Munich-based drug development company, has announced that its wholly owned subsidiary, Curacyte Chemistry GmbH based in Jena, has been awarded a EUR1.2M R&D grant from the German State of Thuringia's Corporate Technology Development Program. The grant will fund the lead optimization and pre-clinical development of the Company's... view more... (2003-10-29)
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