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The good and bad side of anti-cancer compounds
Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells. While they are currently being tested as anti-cancer agents in clinical trials, just how they execute their effects is unclear. view more (2008-04-11)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
COX-2 inhibitors delay pancreatic cancer precursors in mice
Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor, delays the progression of precancerous pancreatic lesions in mice, according to researchers at David Geffen School of Medicine at UCLA. view more (2007-08-02)
Study reveals how some molecules inhibit growth of lung cancer cells
By mapping the interlocking structures of small molecules and mutated protein "receptors" in non-small cell lung cancer (NSCLC) cells, scientists at Dana-Farber Cancer Institute and their colleagues have energized efforts to design molecules that mesh with these receptors, potentially interfering with cancer cell growth and survival. view more (2007-03-13)
Compounds could be new class of cancer drugs
A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer. view more (2009-02-04)
ESC Congress 2003: Striking reduction in mortality after a "heart attack" - A National Study in 2002
IMPORTANT: This press release accompanies a poster or oral session given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology We observed a striking decline in mortality among consecutive patients with "heart attacks" hospitalized in... view more... (2003-08-31)
Study identifies potential drug target for Huntington's disease
An enzyme known to be critical for the repair of damaged cells and the maintenance of cellular energy may be a useful target for new strategies to treat Huntington's disease (HD) and other disorders characterized by low cellular energy levels. view more (2006-07-31)
Study finds implantable defibrillators as effective in women as in men
Women who have had a heart attack get as much survival benefit as men from implanted cardioverter defibrillators (ICDs), devices designed to monitor the heart's pumping rhythm and shock it back to normal when needed, according to a study published in the December edition of the Journal of Cardiovascular Electrophysiology. view more (2005-12-23)
Switching immunosuppressants reduces cancer risk in kidney
Switching to a newer type of immunosuppressant drug may reduce the high rate of skin cancer after kidney transplantation, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. view more (2009-11-02)
Liver disease 'shrunk' by blood-pressure drug
A blood-pressure medicine has been shown to reverse the effects of early-stage liver failure in some patients. view more (2009-06-01)
Safety of antithrombotic treatment in acute coronary syndromes
The management of acute coronary syndromes (with or without ST segment elevation) requires the use of anticoagulants, antiplatelet agents (aspirin, clopidogrel and/or glycoprotein (GP) IIb/IIIa inhibitors), beta-blockers, thrombolytics in some cases, and revascularization / reperfusion. view more (2008-09-03)
ESA selects new Earth Observation missions
For its second cycle of the Earth Explorer Opportunity Missions, ESA has recently selected three proposals to enter feasibility study: ACE+ , an Atmosphere and Climate-Explorer; EGPM, the European contribution to Global Precipitation Mission, and SWARM, a constellation of small satellites to study the dynamics of the Earth`s magnetic field and its... view more... (2002-05-29)
U of I scientist develops enzyme inhibitor that may slow cancer growth
University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future therapeutic uses in medicine, specifically cancer treatment. view more (2006-07-07)
Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
Breast cancer survivors who took a weekly dose of risedronate, sold as Actonel, lost significantly less bone than those who did not take the drug. view more (2007-09-19)
Leeches provide source for cardiovascular drugs
The leech has recently confirmed its biomedical interest for scientists by showing that it contains an extensive list of new potential molecules that may become useful tools in the treatment of cardiovascular diseases. view more (2005-10-26)
MUHC study reveals Vioxx related heart attacks can occur within the first two weeks of use
A quarter of patients who suffered a heart attack while taking Vioxx did so within the first two weeks of taking the drug, a new study published by MUHC investigators reveals. view more (2006-05-03)
Johns Hopkins scientists discover what drives the development of a fatal form of malaria
Platelets - those tiny, unassuming cells that cause blood to clot and scabs to form when you cut yourself - play an important early role in promoting cerebral malaria, an often lethal complication that occurs mostly in children. view more (2008-08-19)
Herbal extract extends life for heart failure patients
An herbal medicinal substance, Crataegus Extract WS®1442, safely extends the lives of congestive heart failure patients already receiving pharmacological treatment for the disease, according to a study presented today at the American College of Cardiology's 56th Annual Scientific Session. Crataegus Extract WS®1442 is an extract of leaves... view more... (2007-03-28)
Statin therapy may lower mortality in heart failure patients
Cholesterol-lowering statin therapy may improve survival in patients with diastolic heart failure (DHF) according to a paper published in Circulation: Journal of the American Heart Association by cardiologists at Wake Forest University Baptist Medical Center. view more (2005-07-25)
DRUG TREATMENT HOPE FOR DEMENTIA (pp 2024, 2031)
The drug rivastigmine may significantly alleviate the symptoms of a common form of dementia, concludes research published in this week's issue of THE LANCET. Dementia with Lewy bodies (DLB) is a common form of dementia in older people, affecting between 15 and 25% of all cases. It is characterised by fluctuating cognitive impairment, attention... view more... (2000-12-13)
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