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Acetaminophen may be linked to asthma in children and adults
New research shows that the widely used pain reliever acetaminophen may be associated with an increased risk of asthma and wheezing in both children and adults exposed to the drug. view more (2009-11-05)
Acute gastric injury due to high-dose analgesics?
Analgesics, NSAIDs and acetaminophen, are commonly used for the relief of fever, headaches, and other minor aches and pains. The gastrointestinal side effects of NSAIDs are well documented and acetaminophen is accepted to be a safe drug for the gastrointestinal system. Acute effects of short-term, especially high-dose NSAID and acetaminophen use... view more... (2008-12-29)
Developing a safer form of acetaminophen
Scientists in Louisiana are reporting development of a process for producing large batches of a new and potentially safer form of acetaminophen, the widely used pain-reliever now the source of growing concern over its potentially toxic effects on the liver. view more (2009-07-16)
What teens don't know about OTC medications can hurt them
Teens, who are starting to make more decisions about their own health care, may not know enough about over-the-counter pain medications to avoid complications or inadvertent misuse. view more (2009-05-05)
Medication effective for acute liver failure in early stages of disease
The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found. view more (2009-10-08)
Acetaminophen or acetylsalicylic acid increases risk of developing chronic kidney failure
People who regularly use high dosages of pain-relievers or antipyretic drugs containing acetaminophen (paracetamol) or acetylsalicylic acid run an increased risk of developing permanent reduced kidney function (chronic renal failure). This was found in a nation-wide Swedish research study published on December 20 in The New England Journal of... view more... (2001-12-21)
Ibuprofen is as effective as acetaminophen with codeine to treat pain in children with arm fractures
Children with arm fractures fared as well with ibuprofen to control their pain as acetaminophen with codeine, according to a new study by researchers at the Medical College of Wisconsin, Milwaukee, and Children's Research Institute. view more (2009-08-18)
Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS' Chemical Research in Toxicology, a monthly journal. view more (2007-09-26)
Unique pattern of gene expression can indicate acetaminophen overdose
In a new study, researchers found they could detect toxic levels of acetaminophen in laboratory animals by analyzing gene expression in the blood. view more (2007-11-01)
Studying the fate of drugs in wastewater
Researchers at the National Institute of Standards and Technology (NIST) have published an interesting study that sheds light on the fate of a familiar pharmaceutical as it enters the waste stream. view more (2005-12-27)
Marshall research shows safe dosages of common pain reliever may help prevent muscle loss and other conditions related to aging
Recent studies conducted by Dr. Eric Blough and his colleagues at Marshall University have shown that use of the common pain reliever acetaminophen may help prevent age-associated muscle loss and other conditions. view more (2009-09-24)
Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength
Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University. view more (2008-04-07)
Acetaminophen safe to use after heart attack but doesn't protect the heart
Acetaminophen is safe to use as a pain reliever and fever reducer after a heart attack, but it does not protect the heart muscle, a new study using sheep and rabbits concluded. view more (2006-05-16)
Reviewers agree on osteoarthritis of the knee
Concerns over the cardiovascular safety of non-steroidal anti-inflammatory drugs (NSAIDs) led to the publication of several sets of fresh guidelines on the treatment of knee osteoarthritis. view more (2007-12-06)
Reactions to last DTaP vaccine not prevented
A red splotch forms where most preschoolers get their fifth, and last, shot of the acellular diphtheria-tetanus-pertussis (DTaP) vaccine, and it can last a few days. view more (2006-03-02)
Common painkillers lower levels of prostate cancer biomarker
Common painkillers like aspirin and ibuprofen appear to lower a man's PSA level, the blood biomarker widely used by physicians to help gauge whether a man is at risk of prostate cancer. view more (2008-09-09)
COX-2 Inhibitors Significantly Reduce Risk of Cancer
Results from a new, five-year study show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by up to 71 percent and may offer similar benefit in the prevention of prostate, colon and lung cancers. view more (2006-04-04)
UNC study: new approach promises greater success for predicting drug safety
A new UNC study published online in the journal Genome Research describes a new, more effective and less costly method for testing drugs for potential toxicity and one that could also result in more people benefiting from existing drugs. view more (2009-05-05)
Frequent use of paracetamol in late pregnancy may double risk of wheezing in young children
Frequent use of the painkiller paracetamol (acetaminophen) after 20 weeks of pregnancy may increase the risk of the babies wheezing as young children, finds a study in Thorax. The findings are based on interviews with over 9,000 pregnant mothers who were taking part in the Avon Longitudinal Study of Parents and Children (ALSPAC). The... view more... (2002-10-25)
Regular use of selective COX-2 inhibitors decreases risk of breast cancer
Regular use of selective COX-2 inhibitors significantly reduces the risk of breast cancer. view more (2006-01-30)
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