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UNC study: new approach promises greater success for predicting drug safety
A new UNC study published online in the journal Genome Research describes a new, more effective and less costly method for testing drugs for potential toxicity and one that could also result in more people benefiting from existing drugs.   view more (2009-05-05)

Frequent use of paracetamol in late pregnancy may double risk of wheezing in young children
Frequent use of the painkiller paracetamol (acetaminophen) after 20 weeks of pregnancy may increase the risk of the babies wheezing as young children, finds a study in Thorax. The findings are based on interviews with over 9,000 pregnant mothers who were taking part in the Avon Longitudinal Study of Parents and Children (ALSPAC). The... view more... (2002-10-25)

Regular use of selective COX-2 inhibitors decreases risk of breast cancer
Regular use of selective COX-2 inhibitors significantly reduces the risk of breast cancer.   view more (2006-01-30)

Anxiety before surgery complicates recovery in children
Children who are anxious before surgery experience a more painful, slow, and complicated postoperative recovery, according to a Yale School of Medicine study published this month in Pediatrics.   view more (2006-08-23)

Action of nitroglycerin for chest pain may place some patients at risk
Definitive evidence to explain how the drug nitroglycerin relieves chest pain has resulted from a new study by Howard Hughes Medical Institute investigators at Duke University Medical Center.   view more (2005-08-16)

Anti-inflammatory drugs may mask prostate cancer marker
Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, may reduce serum levels of the prostate biomarker, PSA (prostate specific antigen), and hence may alter the detection of prostate cancer in individuals who take these medications.   view more (2008-09-08)

Antibiotics: Single largest class of drugs causing liver injury
Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI), reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association (AGA) Institute.   view more (2008-12-01)

Aspirin, Tylenol May Decrease Effectiveness of Vaccines
With flu season in full swing and the threat of H1N1 looming, demand for vaccines is at an all-time high. Although those vaccines are expected to be effective, University of Missouri researchers have found further evidence that some over-the-counter drugs, such as aspirin and Tylenol, that inhibit certain enzymes could impact the effectiveness of... view more... (2009-12-02)

UCSD Researchers Develop 'Smart Petri Dish'
Researchers at the University of California, San Diego have developed what they call a "Smart Petri Dish" that could be used to rapidly screen new drugs for toxic interactions or identify cells in the early stages of cancer circulating through a patient's blood.   view more (2006-06-15)

Usual care often not consistent with clinical guidelines for low back pain
Australian general practitioners often treat patients with low back pain in a manner that does not appear to match the care endorsed by international clinical guidelines, according to a report in the February 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2010-02-09)

Over-the-counter anesthetic gel puts the squeeze on mammogram pain
The simple application of a pain-relieving gel may reduce the breast discomfort some women experience during mammography exams, according to the results of a clinical trial published in the online edition of Radiology.   view more (2008-07-22)

Long-term aspirin use reduces risk for colorectal cancer
A new report from the Nurse's Health Study finds that regular, long-term aspirin use can significantly reduce the risk of colorectal cancer, as suggested by several earlier studies.   view more (2005-08-24)

Medication appears effective in treating teen heroin addiction
In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention.   view more (2005-10-04)

Common Pain Relievers May Dilute Power of Flu Shots
With flu vaccination season in full swing, research from the University of Rochester Medical Center cautions that use of many common pain killers - Advil, Tylenol, aspirin - at the time of injection may blunt the effect of the shot and have a negative effect on the immune system.   view more (2009-11-04)
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