Acid Synthase Current Events | Acid Synthase News
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Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
Obesity drug helps unlock clues about cancer
An approved drug for fighting obesity is helping scientists at Wake Forest University School of Medicine uncover clues about how to stop the growth of cancerous tumors. view more (2007-02-02)
Atomic structure of the mammalian 'fatty acid factory' determined
Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the treatment of metabolic disorders. view more (2008-09-05)
Genetic Testing For Cell-Proliferation Enzyme Could Improve Treatment Of Acute Lymphoblastic Leukaemia (p 1033)
Authors of a Canadian research letter in this week's issue of THE LANCET describe how genetic testing for an enzyme involved in cancer-cell proliferation could identify patients at an increased risk of poor outcome from acute lymphoblastic leukaemia. The enzyme thymidylate synthase is associated with cell proliferation, and is therefore an... view more... (2002-03-20)
Discovery about obesity drug helping scientists develop new cancer treatments
Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments. view more (2007-07-09)
Food additive may one day help control blood lipids and reduce disease risk
Scientists at Washington University School of Medicine in St. Louis have identified a substance in the liver that helps process fat and glucose. That substance is a component of the common food additive lecithin, and researchers speculate it may one day be possible to use lecithin products to control blood lipids and reduce risk for diabetes,... view more... (2009-07-31)
Crystal structure enables tailoring of pharmaceuticals against asthma
Researchers at Karolinska Institutet in Sweden have managed to elucidate the crystal structure of a human membrane protein - LTC4 synthase - which has a major influence on the development of asthma. view more (2007-07-17)
Aminoguanidine: An attractive line as a multi-modal avenue to overcome tumor
Aminoguanidine is a compound that exerts multiple biological actions. Aminoguanidine has well described antioxidant properties and is also an inhibitor of nitric oxide synthases, the enzymes that produce nitric oxide. view more (2009-03-09)
Advance in understanding cellulose synthesis
Cellulose is a fibrous molecule that makes up plant cell walls, gives plants shape and form and is a target of renewable, plant-based biofuels research. view more (2009-06-15)
Formation of cellulose fibers tracked for the first time
Cellulose-a fibrous molecule found in all plants-is the most abundant biological material on Earth. view more (2006-04-21)
ESRF lightsource helps tailoring new treatments against asthma
Researchers from Sweden and France have deciphered the crystal structure of a human membrane protein which has a major influence on the development of asthma. view more (2007-08-03)
Studies find possible drug targets for improving vascular health
The enzyme nitric oxide synthase plays a role in peripheral vascular disease, a common disease that impairs the mobility of 25 percent of people over the age of 50, according to a Yale study in the Proceedings of the National Academy of Sciences (PNAS). view more (2005-08-26)
Intelligently Designed Molecular Evolution
Evolutionary paths to new therapeutic drugs, as well as a wide assortment of other enzyme products, have been created through, of all things, intelligent design. A team of researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley have developed a technique in which the evolution of an... view more... (2006-02-24)
Tuberculosis drug shows promise against latent bacteria
A new study has shown that an investigational drug (R207910, currently in clinical trials against multi-drug resistant tuberculosis strains) is quite effective at killing latent bacteria. This revelation suggests that R207910 may lead to improved and shortened treatments for this globally prevalent disease. view more (2008-09-15)
Epilepsy drug may help Alzheimer's patients
A popular epilepsy drug may also be beneficial in patients with Alzheimer's disease (AD), according to a new study to be published on October 27 in the Journal of Experimental Medicine. The anti-seizure drug valproic acid improved memory and reduced brain lesions in mice with an AD-like disease. view more (2008-10-27)
No Increased Risk of Miscarriage From Folic Acid Supplements (p 796)
Women who consume folic acid supplements around the time of conception are not at an increased risk of miscarriage, conclude authors of a population-based study published in this weke’s issue of THE LANCET. Although it is well known that folic acid supplements can reduce the risk of infant neural-tube defects (NTDs), its effects on other... view more... (2001-09-05)
Folic acid deficit increased risk of miscarriage in early pregnancy
Low levels of folic acid in plasma have been associated with an increased risk of miscarriage in a study published in Journal of the American Medical Association lately. On the other hand, no connection was found between high levels of folic acid and increased risk of miscarriage. In the US folic acid is added to flour to prevent pregnant women... view more... (2002-10-22)
Evidence for warts treatments is weak
Apart from topical treatments containing salicylic acid, there is currently no clear evidence that any other treatments for warts are more effective, say researchers in this week’s BMJ. view more (2002-08-28)
Genome of PURAC's lactic acid-producing micro-organism completed by Greenomics™
PURAC and Greenomics™ (Plant Research International B.V.) announced the completion of the whole-genome sequencing of a production strain of PURAC that produces high amounts of lactic acid. Greenomics™ conducted the shotgun cloning and high quality sequencing of the genome up to a zero-gap situation. The closed genome is accompanied by... view more... (2002-05-14)
Elevated arginase levels contribute to vascular eye disease such as diabetic retinopathy
Elevated levels of the enzyme arginase contribute to vascular eye damage and Medical College of Georgia researchers say therapies to normalize its levels could halt progression of potentially blinding diseases such as diabetic retinopathy. view more (2009-08-18)
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