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Genetic Testing For Cell-Proliferation Enzyme Could Improve Treatment Of Acute Lymphoblastic Leukaemia (p 1033)
Authors of a Canadian research letter in this week's issue of THE LANCET describe how genetic testing for an enzyme involved in cancer-cell proliferation could identify patients at an increased risk of poor outcome from acute lymphoblastic leukaemia. The enzyme thymidylate synthase is associated with cell proliferation, and is therefore an... view more... (2002-03-20)

New genes involved in Acute Lymphoblastic Leukemia play fundamental role in prognosis of the disease
The inactivity or "silence" of certain genes plays a fundamental role in the prognosis of acute lymphoblastic leukemia (ALL) as well as in response to treatment, according to the results of research involving a team made up of specialists from the University Hospital of Navarra and the Centre for Applied Medical Research (CIMA) at the... view more... (2009-02-09)

FOLATE SUPPLEMENTS DURING PREGNANCY COULD PROTECT AGAINST LEUKAEMIA (p 1935)
A population-based study from Western Australia in this week's issue of THE LANCET suggests that folate and iron supplementation during pregnancy might be associated with a decreased risk of childhood acute lymphoblastic leukaemia (ALL). ALL is the most common childhood cancer in more-developed countries but it has few recognised risk factors or... view more... (2001-12-05)

Household insecticides associated with increased risk of childhood leukaemia
Household insecticides may increase the risk of childhood leukaemia, suggests French research in Occupational and Environmental Medicine.   view more (2006-01-17)

GENETIC EVIDENCE FOR LINK BETWEEN COSMIC RADIATION AND LEUKAEMIA IN AIRCREW (p 2158)
The association between exposure to cosmic radiation and leukaemia among aircrew is strengthened by genetic research published in this week's issue of THE LANCET. Previous research by Maryanne Gundestrup and colleagues from the Institute of Cancer Epidemiology, Copenhagen, Denmark (Radiation-induced acute myeloid leukaemia and other cancers in... view more... (2000-12-21)

A new treatment for T-cell acute lymphoblastic leukaemia?
IL-7, a hormone-like protein involved in cell-cell interaction, has been associated with increased survival and expansion of T-cell acute lymphoblastic leukaemia (T-ALL). Now, in the latest issue of the Journal of Experimental Medicine, a team of scientists, not only confirms the essential role of this protein in the disease but also, for the... view more... (2004-09-09)

A new line of treatment discovered for acute lymphoblastic leucemia
A study undertaken by a group of Spanish scientists, amongst which were members of the University Clinic of the University of Navarra and the Centre for Applied Medical Research (CIMA) of the same university, have recently discovered a new line of treatment for patients with acute lymphoblastic leucemia.   view more (2007-02-12)

New research provides hope for childhood cancer sufferers
Scientists investigating drug therapies for children with Acute Lymphoblastic Leukaemia (ALL) have presented new data demonstrating for the very first time that a small molecule called ABT-737 can increase the effectiveness of standard therapies.   view more (2007-07-17)

New test piloted for childhood leukaemia
A new screening test to be piloted in Bristol could help to revolutionise the way children with leukaemia are treated by enabling doctors to fine tune treatment to the needs of each individual patient. Experts from five centres - Bristol, Glasgow, Leeds, London and Sheffield - will pilot the test for the most common form of the childhood leukaemia... view more... (2002-08-05)

Rate of secondary cancers increases over years after treatment for childhood leukemia
Survivors of acute lymphoblastic leukemia have a significantly increased risk of secondary cancers developing over 30 years after leukemia treatment when compared to the general population.   view more (2007-03-21)

Women cured of childhood leukaemia should be advised to have children while they are young
Vienna, Austria: Women who have survived having leukaemia as children should receive fertility counselling because their reproductive life may be shortened even though they have an apparently normal menstrual cycle after treatment, according to Danish researchers. Dr Elisabeth Larsen, a research assistant from the Fertility Clinic at Copenhagen... view more... (2002-07-01)

Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
Scientists in Switzerland are uncovering new clues about how cancer cells grow - and how they can be killed - by studying stem cells, 'blank' cells that have the potential to develop into fully mature or 'differentiated' cells and other scientists in UK have made a breakthrough in understanding the cause of the most common form of childhood... view more... (2008-02-14)

Deakin University discovery could lead to new leukaemia treatments
Deakin University scientists have identified a protein that could hold the key to new leukaemia treatments.   view more (2006-11-07)

Researchers identify cells that make relapse inevitable in acute lymphoblastic leukemia
In "Dr Jekyll and Mr Hyde" Robert Louis Stevenson wrote about the good and evil sides of the same person; now scientists in Australia have discovered that in acute lymphoblastic leukaemia (ALL) there are Dr Jekyll and Mr Hyde cells - "good" and "evil" clones of the same type of ALL cell.   view more (2006-11-09)

New analysis finds daycare attendance early in life cuts childhood leukemia risk by 30 percent
Children who attend day care or play groups have about a 30% lower risk of developing the most common type of childhood leukaemia than those who do not, according to a new analysis of studies investigating the link.   view more (2008-04-28)

Cash boost for research into leukaemia
Scientists from the University of Sussex in Brighton have been awarded £147,000 by the Leukaemia Research Fund (LRF) to look at abnormalities in DNA damage and repair that occur in some leukaemias and lymphomas. The research team ¾ led by Dr Penny Jeggo at the Genome Damage and Stability Centre ¾ will look at Seckel Syndrome, a rare... view more... (2002-09-11)

Research Will Push Forward Fight Against Leukaemia
A project which aims to make laboratory-grown leukaemia cells change form and then be used to prime a patient's own immune system to kill off malignant cells has begun in Edinburgh. If successful, the study could give clinicians a way of destroying residual leukaemic cells which are undetectable by microscope. The findings could be helpful in the... view more... (2002-10-25)

New test proves effective in more cancers
Avantogen Limited (ACU:ASX) today announced that cancer researchers at Perth's Telethon Institute for Child Health Research (TICHR) and Avantogen Limited have achieved an important milestone towards more individually targeted and effective treatments for cancer patients.   view more (2005-10-07)

St. Jude discovery offers new avenues to understanding an aggressive form of leukemia
Researchers at St. Jude Children”¦s Research Hospital have discovered evidence that a series of genetic mutations work together to initiate most cases of an aggressive and often-fatal form of acute lymphoblastic leukemia (ALL).   view more (2008-04-15)

MGH study identifies first molecular steps to childhood leukemia
A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) - the most common cancer in children - initiates the disease process.   view more (2009-07-16)
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