Acute Lymphoblastic Leukemia Current Events | Acute Lymphoblastic Leukemia News | 3
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UC Davis researchers shed new light on how chemotherapy-induced leukemia develops
Topoisomerase II inhibitors are among the most successful chemotherapy drugs used to treat human cancer. view more (2005-11-16)
Inherited genes linked to toxicity of leukemia therapy
Investigators at St. Jude Children's Research Hospital have discovered inherited variations in certain genes that make children with acute lymphoblastic leukemia (ALL) susceptible to the toxic side effects caused by chemotherapy medications. view more (2007-05-14)
Inherited risk factors increase odds of developing childhood acute lymphoblastic leukemia
Scientists at St. Jude Children's Research Hospital have identified inherited variations in two genes that account for 37 percent of childhood acute lymphoblastic leukemia (ALL), including a gene that may help predict drug response. view more (2009-08-17)
Study of leukemia survivors gives hints for better care
Results from the longest follow-up study ever done of childhood acute lymphoblastic leukemia (ALL) survivors show the importance of long-term monitoring of former patients to identify complications they are at risk for developing later in life and to modify current treatments to reduce those risks. view more (2007-03-21)
St. Jude finds factors that accelerate resistance to targeted therapy in lymphoblastic leukemia
Results of a study by investigators at St. Jude Children's Research Hospital provide strong evidence for why the targeted therapy drug imatinib (Gleevec™), which has revolutionized the treatment of chronic myelogenous leukemia (CML), is often unable to prevent relapse of a particularly aggressive form of acute lymphoblastic leukemia (ALL). view more (2007-08-30)
Antioxidant found in many foods and red wine is potent and selective killer of leukemia cells
A naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells in culture while showing no discernible toxicity against healthy cells. view more (2007-04-24)
AMN107 has potent activity in leukemia resistant to Gleevec
The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center. view more (2005-12-12)
A Broken Stress Response System Can Contribute to Gleevec Resistance
New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report. view more (2006-04-21)
Shilatifard and colleagues identify a potential target for treatment of mixed lineage leukemia
Ali Shilatifard, Ph.D., Investigator, has identified a cellular factor that can reverse histone trimethylation caused by the trithorax gene, the Drosophila homologue of the human mixed lineage leukemia gene, MLL. MLL, which is found in translocations in a variety of hematological malignancies, is a histone H3K4 methyltransferase. view more (2007-03-12)
Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
Scientists in Switzerland are uncovering new clues about how cancer cells grow - and how they can be killed - by studying stem cells, 'blank' cells that have the potential to develop into fully mature or 'differentiated' cells and other scientists in UK have made a breakthrough in understanding the cause of the most common form of childhood... view more... (2008-02-14)
Groundbreaking study shows exercise benefits leukemia patients
One of the most bothersome symptoms of leukemia is extreme fatigue, and asking these patients to exercise doesn't sound like a way to help them feel better. view more (2009-08-03)
Scoring system identifies MDS patients who have low-risk disease but a poor prognosis
A new scoring system for a form of leukemia known as myelodysplastic syndrome (MDS) identifies patients who appear to have low-risk disease but actually have poor prospects of survival, researchers at The University of Texas M. D. Anderson Cancer Center report online at the journal Leukemia. view more (2007-12-27)
Dual functions of gene revealed, for better and for worse
Researchers at WEHI have pinpointed the function of a potent cancer gene. The gene, known as "ERG", has long been associated with a range of human malignancies, including leukemia and sarcoma. American scientists showed in 2005 that ERG is mutated in more than half of all prostate cancers. view more (2008-05-27)
Cancer scientists create 'human' leukemia process to map how disease begins, progresses
Cancer researchers led by Dr. John Dick at Ontario Cancer Institute (OCI) have developed a method to convert normal human blood cells into "human" leukemia stem cells. view more (2007-04-27)
Steroids and chicken pox not a good mix
Children who have been treated with steroids and are exposed to chicken pox tend to have a more severe case of the virus. view more (2005-10-19)
Mutant genes in high-risk childhood leukemias identified
A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblastic leukemia (ALL) that have a high risk of relapse and death. view more (2009-05-20)
Scientists isolate leukemia stem cells in a model of human leukemia
Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston and their colleagues have isolated rare cancer stem cells that cause leukemia in a mouse model of the human disease. view more (2006-07-18)
New strategy in tumor treatment
A new strategy proposed by researchers at Dartmouth Medical School and Amtek, Hanover, NH may treat tumors that do not respond to conventional treatment. view more (2009-07-20)
Gene mutation improves leukemia drug's effect
Gene mutations that make cells cancerous can sometimes also make them more sensitive to chemotherapy. A new study led by cancer researchers at Ohio State University shows that a mutation present in some cases of acute leukemia makes the disease more susceptible to high doses of a particular anticancer drug. view more (2008-06-18)
New studies identify advances in treatment of chronic myeloid leukemia
Offering promise in the battle against cancer, the results from five studies highlighting new advances in the treatment of chronic myeloid leukemia (CML) - a slow-progressing, malignant bone marrow cancer - will be presented at the 47th Annual Meeting of the American Society of Hematology. view more (2005-12-12)
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