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Acute Lymphoblastic Leukemia Current Events | Acute Lymphoblastic Leukemia News | 5

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Researchers identify cells that make relapse inevitable in acute lymphoblastic leukemia
In "Dr Jekyll and Mr Hyde" Robert Louis Stevenson wrote about the good and evil sides of the same person; now scientists in Australia have discovered that in acute lymphoblastic leukaemia (ALL) there are Dr Jekyll and Mr Hyde cells - "good" and "evil" clones of the same type of ALL cell.   view more (2006-11-09)

OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML).   view more (2007-12-10)

Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor
This research validates the potential for Stapled Peptides to modulate key intracellular biological targets, such as transcription factors, that have not been addressable with current small molecule or biologic drug modalities.   view more (2009-11-12)

ESC Congress 2003: Acute Heart Failure Guidelines
IMPORTANT: This press release accompanies a presentation given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology ESC Congress 2003: Acute Heart Failure Guidelines   view more (2003-09-03)

A case of post-gastrectomy acute pancreatitis
Gastrectomy is commonly performed for both benign and malignant lesions. Although the incidence of post-gastrectomy acute pancreatitis (PGAP) is low compared to other well-recognized post-operative complications, it has been reported to be associated with a high mortality rate.   view more (2009-10-16)

Lenalidomide safe as single therapy for elderly CLL patients
The oral medication lenalidomide is safe and well-tolerated for elderly patients with chronic lymphocytic leukemia, a group without a well-defined frontline therapy for their disease, researchers from The University of Texas M. D. Anderson Cancer Center reported today at the 50th annual meeting of the American Society of Hematology.   view more (2008-12-08)

Warning over nitric oxide for lung injury patients
Use of nitric oxide in patients with acute lung injury does not improve survival and may cause harm, warn researchers in a study published on bmj.com today.   view more (2007-03-23)

Leukemic cells find safe haven in bone marrow
The cancer drug asparaginase fails to help cure some children with acute lymphoblastic leukemia (ALL) because molecules released by certain cells in the bone marrow counteract the effect of that drug, according to investigators at St. Jude Children's Research Hospital.   view more (2007-03-23)

Novel strategy under study for aggressive leukemia
A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say.   view more (2007-09-25)

A miR boost enables acute leukemia cells to mature
A new study by Ohio State University cancer researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) cells can reverse gene changes that trap the cells in an immature, fast growing state of development.   view more (2009-04-03)

St. Jude unlocks mystery of very aggressive leukemia
Investigators at St. Jude Children's Research Hospital have used mouse models to determine why some forms of acute lymphoblastic leukemia (ALL) are extremely aggressive and resist a drug that is effective in treating a different type of leukemia.   view more (2006-04-20)

Oxygen treatment for severe asthma could save lives
Asthmatic patients are still dying during severe attacks, yet making oxygen available in every general practice to treat patients with a life threatening asthma attack could save lives, concludes a study in this week's BMJ. The authors urge the British Thoracic Society to review this issue when it updates its asthma guidelines. A research team in... view more... (2001-07-11)

Survey: Few physicians support private banking of umbilical cord blood
A survey of physicians has found broad support for the position that parents should not bank their newborns' umbilical cord blood in a private blood bank unless another member of the family is at risk for a blood disease that will require a stem cell transplant.   view more (2009-03-09)

New insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors.   view more (2008-08-21)

Giving patients more information reduces antibiotic use
General practitioners prescribe antibiotics to three-quarters of UK adults with acute bronchitis each year, even though there is little evidence to justify it. Yet, a study in this week's BMJ finds that reassuring these patients and sharing the uncertainty about prescribing in an information leaflet reduces antibiotic use.   view more (2002-01-09)

Household insecticides associated with increased risk of childhood leukaemia
Household insecticides may increase the risk of childhood leukaemia, suggests French research in Occupational and Environmental Medicine.   view more (2006-01-17)

New test piloted for childhood leukaemia
A new screening test to be piloted in Bristol could help to revolutionise the way children with leukaemia are treated by enabling doctors to fine tune treatment to the needs of each individual patient. Experts from five centres - Bristol, Glasgow, Leeds, London and Sheffield - will pilot the test for the most common form of the childhood leukaemia... view more... (2002-08-05)

Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard immunosuppressant drugs after kidney transplants. Treatment... view more... (2003-04-10)

Grape-seed extract kills laboratory leukemia cells, proving value of natural compounds
An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract.   view more (2009-01-05)

Ultrasound first, not CT, for diagnosing suspected acute appendicitis
Color Doppler ultrasound, not CT, should be the first imaging examination for adult patients with suspected acute appendicitis, a new study emphasizes.   view more (2008-05-08)
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