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GENETIC EVIDENCE FOR LINK BETWEEN COSMIC RADIATION AND LEUKAEMIA IN AIRCREW (p 2158)
The association between exposure to cosmic radiation and leukaemia among aircrew is strengthened by genetic research published in this week's issue of THE LANCET. Previous research by Maryanne Gundestrup and colleagues from the Institute of Cancer Epidemiology, Copenhagen, Denmark (Radiation-induced acute myeloid leukaemia and other cancers in... view more... (2000-12-21)

Enhancing the effects of the drug used to treat chronic myeloid leukemia
Individuals with chronic myeloid leukemia (CML) are first treated with a drug known as imatinib mesylate. Although very effective, as the disease progresses it often becomes resistant to the drug.   view more (2009-04-14)

Van Andel Institute Researchers Find Gene that Could Lead to New Therapies for Bone Marrow Disease
Van Andel Research Institute (VARI) researchers are one step closer to finding new ways to treat Myelodysplastic Syndrome (MDS), a bone marrow disease that strikes up to 15,000 people each year in the United States, and that sometimes results in acute myeloid leukemia.   view more (2009-09-29)

Study identifies molecular process underlying leukemia
New research from the University of North Carolina at Chapel Hill has identified a molecular process in cells that is crucial to the development of two common leukemias.   view more (2006-08-22)

Stripping leukemia-initiating cells of their 'invisibility cloak'
Two new studies reveal a way to increase the body's appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate.   view more (2009-07-24)

OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML).   view more (2007-12-10)

Finding key to cancer drug Gleevec's limitations
University of Michigan researchers have developed an animal model that provides strong evidence why imatinib, marketed as Gleevec, helps patients with chronic myeloid leukemia survive longer, but does not keep the disease from returning if treatment ends.   view more (2009-08-05)

Rate of secondary cancers increases over years after treatment for childhood leukemia
Survivors of acute lymphoblastic leukemia have a significantly increased risk of secondary cancers developing over 30 years after leukemia treatment when compared to the general population.   view more (2007-03-21)

Researchers find drug that inhibits acute leukemia cell growth
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have discovered how to turn off a certain receptor that promotes the growth of leukemia cells.   view more (2009-04-27)

Data presented demonstrate prolonged overall survival for patients with acute myeloid leukemia
The Myelodysplastic Syndromes (MDS) Foundation announced today that data presented at this year's American Society of Hematology (ASH) Meeting in San Francisco demonstrate that patients with acute myeloid leukemia (AML) who were treated with VIDAZA (azacitidine) had significantly increased overall survival compared to those treated with... view more... (2008-12-11)

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
The most comprehensive analysis yet of the genome of childhood acute myeloid leukemia (AML) found only a few mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps.   view more (2009-07-28)

Molecules might identify high-risk acute-leukemia patients
New research suggests that certain small molecules used by cells to control the proteins they make might also help doctors identify adult acute-leukemia patients who are likely to respond poorly to therapy.   view more (2008-01-16)

Targeting leukemic stem cells by Bcl-2 inhibition
Researchers at The University of Texas M. D. Anderson Cancer Center have found, in laboratory studies, that the experimental drug ABT-737 which has shown promise in some cancers, can destroy acute myeloid leukemia (AML) blast, progenitor and even stem cells that are often resistant to standard chemotherapy treatment.   view more (2006-11-20)

Vaccine improves event-free survival for leukemia patients
Patients whose immune system responded to a peptide vaccine for leukemia enjoyed a median remission that was more than three times longer than non-responders, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports at the 49th Annual Meeting of the American Society of Hematology.   view more (2007-12-10)

Toronto researcher's discovery points to a new treatment avenue for acute myeloid leukemia
Dr. John Dick, Senior Scientist at the Ontario Cancer Institute, the research arm of Princess Margaret Hospital, co-led a multinational team that has developed the first leukemia therapy that targets a protein, CD123, on the surface of cancer stem cells that drive acute myeloid leukemia (AML), which is an aggressive disease with a poor outcome.   view more (2009-07-07)

The genetics of MLL leukemogenesis
In the November 1st issue of G&D, Dr. Michael Cleary (Stanford University School of Medicine) and colleagues identify the gene Meis1 as a critical player in the establishment of leukemia stem cells, and the development of MLL leukemia.   view more (2007-10-17)

Modified bone marrow cells can help recovery in an animal model of multiple sclerosis
A new study published in PLoS Medicine has shown that modified bone marrow cells can help recovery in an animal model of multiple sclerosis (MS).   view more (2007-04-10)

Novel drug preventing protein recycling shows potential for treating leukemia
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found that a novel targeted therapy effectively treats acute leukemia in animal models by preventing cancer cells from being purged of damaged proteins.   view more (2007-04-20)

Daisies lead scientists down path to new leukemia drug
A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood.   view more (2007-10-03)

CDX2 — A protein that promotes leukemia
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells.   view more (2007-03-08)
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