Acute Myeloid Leukemia Current Events | Acute Myeloid Leukemia News | 2
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CDX2 — A protein that promotes leukemia
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells. view more (2007-03-08)
AMN107 has potent activity in leukemia resistant to Gleevec
The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center. view more (2005-12-12)
MGH study identifies first molecular steps to childhood leukemia
A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) - the most common cancer in children - initiates the disease process. view more (2009-07-16)
A lethal cancer knocked down by one-two drug punch
In the battle against cancer, allies can come from unexpected sources. Research at The Jackson Laboratory has yielded a new approach to treating leukemia, one that targets leukemia-proliferating cells with drugs that are already on the market. view more (2009-06-08)
Dartmouth researchers find that arsenic triggers unique mechanism in rare leukemia
Dartmouth Medical School (DMS) researchers have identified a new way that arsenite, a form of arsenic, acts in treating a rare cancer known as APL, or acute promyelocytic leukemia. Their study is published in the Jan. 3 issue of the Journal of the National Cancer Institute. view more (2007-01-09)
Mouse model reveals that oncoprotein induces abnormal preleukemic blood cell progenitors
Scientists have developed a novel mouse model for leukemia that reveals critical information about the mechanisms involved in leukemia progression and provides a model system for evaluation of new drugs for treatment of leukemia. view more (2006-01-18)
Gene mutation improves leukemia drug's effect
Gene mutations that make cells cancerous can sometimes also make them more sensitive to chemotherapy. A new study led by cancer researchers at Ohio State University shows that a mutation present in some cases of acute leukemia makes the disease more susceptible to high doses of a particular anticancer drug. view more (2008-06-18)
Research on the effects of stem cell source and patient age on transplantation outcomes
Blood cancers - leukemia, lymphoma, and myeloma - are typically treated with a combination of treatments including chemotherapy, biological therapy, radiation therapy, and stem cell transplantation. Stem cell transplantation is the process by which blood stem cells are collected from a donor, or from the patient prior to chemotherapy, and then... view more... (2008-12-08)
OHSU Cancer Institute researchers identify new approach to help control drug resistance in leukemia
Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML). The results of their study will be published the week of March 24th in the Proceedings of the National Academy of Sciences. view more (2008-03-25)
Research shows cord blood comparable to matched bone marrow
University of Minnesota researchers report that umbilical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, according to an analysis of outcome data performed at the Center for International Blood and Marrow Transplant Research (CIBMTR), Medical College of Wisconsin, Milwaukee. view more (2007-06-08)
Lymphocyte count found to be a predictor of survival for young patients with leukemia
One simple blood test could predict relapse or survival for children and young adults with acute leukemias. view more (2007-05-08)
Experimental agents may prevent radiation-induced leukemia
Treatment with biphosphonates could prevent radiation-induced leukemia, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009. view more (2009-04-20)
Gene therapy protocol at UCSD activates immune system in patients with leukemia
A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells. view more (2008-02-12)
Arsenic-based therapy shown to help eradicate leukemia-initiating cells
In both leukemia and solid tumors, there exists among the multitude of warrior cancer cells a small subgroup that work undercover, patiently lying in wait to launch their attacks. view more (2008-05-13)
A miR boost enables acute leukemia cells to mature
A new study by Ohio State University cancer researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) cells can reverse gene changes that trap the cells in an immature, fast growing state of development. view more (2009-04-03)
New strategy rapidly identifies cancer targets
In a step toward personalized medicine, Howard Hughes Medical Institute investigator Brian J. Druker and colleagues have developed a new technique to identify previously unknown genetic mutations that can trigger cancerous growth. view more (2006-07-17)
Cells on path to becoming mature T-cells more flexible than commonly thought
Contrary to the currently accepted model of T-cell development, researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types versus only being committed to the T-cell path. view more (2008-04-10)
Progress toward a targeted therapy for a specific form of leukemia
Leukemia, or cancer of the bone marrow, strikes some 700 Belgians each year. Scientists are still searching for the cause of many forms of leukemia, including T-cell acute lymphoblastic leukemia, or T-ALL. view more (2007-04-16)
New Drug for Children with High-Risk Leukemia
Each year, approximately 4,500 children in America are diagnosed with leukemia, according to the Leukemia and Lymphoma Society. A potentially deadly cancer of the blood, it is the most common cancer in children. view more (2009-07-29)
Promising target for new atherosclerosis therapies linked to leukemia
In recent years, scientists studying inflammation and atherosclerosis have seen their respective fields converging. Inflammation is an aspect of the immune response to injury and disease; atherosclerosis, with its characteristic lesions in the blood vessel walls, underlies most cardiovascular disease, including heart attacks and strokes. view more (2006-11-02)
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