Acute Myeloid Leukemia Current Events | Acute Myeloid Leukemia News | 4
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St. Jude identifies genomic causes of a certain type of leukemia relapse
Scientists at St. Jude Children's Research Hospital have identified distinctive genetic changes in the cancer cells of children with acute lymphoblastic leukemia (ALL) that cause relapse. The finding offers a pathway to designing treatments for ALL relapse in children and, ultimately, in adults. view more (2008-12-01)
Leukemia drug proves safe and effective over the long term
The drug imatinib mesylate, more commonly known as Gleevec, proves safe and effective over the long term in patients with an advanced form of chronic myeloid leukemia (CML), according to a study prepublished online in Blood, the official journal of the American Society of Hematology. view more (2007-11-08)
Clinical trial demonstrates safety of pre-transplant expansion of umbilical cord blood stem cells
Taking blood stem cells collected from an umbilical cord into the lab and expanding their number before transplanting them to replace a patient's blood supply is as safe as a standard cord blood transplant, researchers reported today at the 50th Annual Meeting of the American Society of Hematology. view more (2008-12-09)
Scientists uncover indicator that warns leukemia is progressing to more dangerous form
Scientists at the Moores Cancer Center at the University of California, San Diego, Stanford University School of Medicine and other centers have identified a mechanism by which a chronic form of leukemia can progress into a deadlier stage of the disease. view more (2009-02-17)
Scientists isolate leukemia stem cells in a model of human leukemia
Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston and their colleagues have isolated rare cancer stem cells that cause leukemia in a mouse model of the human disease. view more (2006-07-18)
Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. view more (2008-04-11)
Scientists identify key gene that protects against leukemia
Researchers have identified a gene that controls the rapid production and differentiation of the stem cells that produce all blood cell types-a discovery that could eventually open the door to more streamlined treatments for leukemia and other blood cancers, in which blood cells proliferate out of control. view more (2009-04-09)
Scientists discover new role for miRNA in leukemia
Scientists here have found that mini-molecules called micro-RNA may play a critical role in the progression of chronic myeloid leukemia (CML) from its more treatable chronic phase to a life-threatening phase, called blast crisis. view more (2007-12-10)
Combining math and medicine to treat leukemia
Researchers have produced a mathematical model that may lead to the development of an optimally-timed vaccine for chronic myelogenous leukemia (CML). view more (2008-06-20)
New treatment for specific type of leukemia
Leukemia - or cancer of the bone marrow - strikes some 700 Belgians each year. Chronic Eosinophilic Leukemia (CEL), a specific form of leukemia, is currently treated with Glivec. However, recent research has shown that prolonged usage can cause resistance to Glivec, rendering this chronic form of leukemia untreatable. view more (2006-05-10)
Mayo clinic reports some chronic leukemia patients may improve by taking an extract of green tea
A new case study by Mayo Clinic researchers provides preliminary evidence to suggest a component of green tea may lead to clinical improvement in patients with chronic lymphocytic leukemia (CLL). Findings are published online in Leukemia Research. view more (2005-12-14)
Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow. view more (2005-08-02)
Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body. view more (2007-04-19)
What are the risk factors for rebleeding after negative angiography?
Acute non-variceal gastrointestinal bleeding accounts for approximately 20% of emergency room visits and 5% of admissions. view more (2009-09-16)
The good and bad side of anti-cancer compounds
Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells. While they are currently being tested as anti-cancer agents in clinical trials, just how they execute their effects is unclear. view more (2008-04-11)
Three molecular triggers threaten leukemia patients
The road to better treatment for the most common form of adult leukemia will require blocking multiple molecular pathways that fuel the disease. view more (2006-10-04)
Acute pancreatitis and cholangitis: a complication caused by a migrated gastrostomy tube
Percutaneous endoscopic gastrostomy (PEG) is generally considered to be safe with a low rate of serious complications. However, dislocation of a gastrostomy tube can lead to serious complications. view more (2007-10-25)
Survivors of childhood leukemia, brain tumors more at risk for strokes later in life
Children who are successfully treated for brain tumors or leukemia are more likely to have strokes later in life, according to new research from UT Southwestern Medical Center. view more (2006-11-20)
Unique role for blood formation gene identified
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. view more (2007-09-13)
New hope for patients with chronic lymphocytic leukemia
Patients treated with lenalidomide for relapsed chronic lymphocytic leukemia (CLL) or disease that no longer responds to chemotherapy have experienced a major response to therapy, according to a phase II study conducted by Asher Chanan-Khan, MD, Department of Medicine, Roswell Park Cancer Institute (RPCI). The results are published in the December... view more... (2006-12-05)
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