Acute Myeloid Leukemia Current Events | Acute Myeloid Leukemia News | 5
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St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia
The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children's Research Hospital study. view more (2008-04-16)
Study of leukemia survivors gives hints for better care
Results from the longest follow-up study ever done of childhood acute lymphoblastic leukemia (ALL) survivors show the importance of long-term monitoring of former patients to identify complications they are at risk for developing later in life and to modify current treatments to reduce those risks. view more (2007-03-21)
Genetic Testing For Cell-Proliferation Enzyme Could Improve Treatment Of Acute Lymphoblastic Leukaemia (p 1033)
Authors of a Canadian research letter in this week's issue of THE LANCET describe how genetic testing for an enzyme involved in cancer-cell proliferation could identify patients at an increased risk of poor outcome from acute lymphoblastic leukaemia. The enzyme thymidylate synthase is associated with cell proliferation, and is therefore an... view more... (2002-03-20)
ESC Congress 2003: Acute Heart Failure Guidelines
IMPORTANT: This press release accompanies a presentation given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology ESC Congress 2003: Acute Heart Failure Guidelines view more (2003-09-03)
A case of post-gastrectomy acute pancreatitis
Gastrectomy is commonly performed for both benign and malignant lesions. Although the incidence of post-gastrectomy acute pancreatitis (PGAP) is low compared to other well-recognized post-operative complications, it has been reported to be associated with a high mortality rate. view more (2009-10-16)
New treatment more than doubles survival for high risk childhood leukemia
Results of a phase two clinical trial published October 5th in the Journal of Clinical Oncology show that adding continuous daily doses of a targeted drug called imatinib mesylate to regular chemotherapy more than doubled three-year survival rates for children with a high risk type of blood cancer called Philadelphia chromosome-positive acute... view more... (2009-10-07)
Lenalidomide safe as single therapy for elderly CLL patients
The oral medication lenalidomide is safe and well-tolerated for elderly patients with chronic lymphocytic leukemia, a group without a well-defined frontline therapy for their disease, researchers from The University of Texas M. D. Anderson Cancer Center reported today at the 50th annual meeting of the American Society of Hematology. view more (2008-12-08)
Warning over nitric oxide for lung injury patients
Use of nitric oxide in patients with acute lung injury does not improve survival and may cause harm, warn researchers in a study published on bmj.com today. view more (2007-03-23)
Novel strategy under study for aggressive leukemia
A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say. view more (2007-09-25)
Oxygen treatment for severe asthma could save lives
Asthmatic patients are still dying during severe attacks, yet making oxygen available in every general practice to treat patients with a life threatening asthma attack could save lives, concludes a study in this week's BMJ. The authors urge the British Thoracic Society to review this issue when it updates its asthma guidelines. A research team in... view more... (2001-07-11)
Ireland Cancer Center researchers advance stem cell gene therapy
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects. view more (2007-12-13)
First gene associated with myeloproliferative diseases
Myelodysplastic / myeloproliferative diseases (MDS/MPD) are blood stem cell disorders characterized by ineffective formation and development of blood cells in the bone marrow, resulting in abnormal development of bone marrow precursor cells and a reduction in the number of blood cells. view more (2005-08-26)
Can cancer drugs combine forces?
Individuals with chronic myeloid leukemia (CML) are treated first with a drug known as imatinib (Gleevec), which targets the protein known to cause the cancer (BCR-ABL). view more (2007-08-17)
New insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors. view more (2008-08-21)
Molecular science could further improve leukemia survival, say St. Jude researchers
The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia (ALL) will be difficult to replicate in older patients without considerable additional research. view more (2008-03-24)
Giving patients more information reduces antibiotic use
General practitioners prescribe antibiotics to three-quarters of UK adults with acute bronchitis each year, even though there is little evidence to justify it. Yet, a study in this week's BMJ finds that reassuring these patients and sharing the uncertainty about prescribing in an information leaflet reduces antibiotic use. view more (2002-01-09)
Household insecticides associated with increased risk of childhood leukaemia
Household insecticides may increase the risk of childhood leukaemia, suggests French research in Occupational and Environmental Medicine. view more (2006-01-17)
Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard immunosuppressant drugs after kidney transplants. Treatment... view more... (2003-04-10)
Study finds overall health and quality of life intact 10 years after stem-cell transplantation
Survivors of stem-cell transplantation for blood cancers can expect to be just about as healthy 10 years later as adults who have never had a transplant, according to a new study by researchers at Fred Hutchinson Research Cancer Center. view more (2005-09-19)
Grape-seed extract kills laboratory leukemia cells, proving value of natural compounds
An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract. view more (2009-01-05)
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