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OHSU lab finds meth receptor that could lead to therapy
A recently discovered signaling system in the brain has just been shown to be turned on by methamphetamine, an Oregon Health & Science University study found. view more (2007-04-19)
Daily alcohol intake can lead to binge drinking
Sipping wine, beer or spirits three to four times per week increases the risk of binge drinking, particularly among young men, according to a new study published in the journal Addiction. view more (2009-05-29)
Chromosome regions containing genes related to alcohol addiction affect drinking behavior in smokers
Scientists have found in a study of tobacco users that their drinking behavior is linked to some of the same chromosome regions associated with alcohol addiction. view more (2005-12-22)
National rates of co-occurring substance use and mental disorders call for better service integration
Canadians are becoming aware of the prevalence of mental health issues and of substance use problems, but how well equipped are we to help the many people who contend with both? view more (2008-12-18)
If your first cigarette gave you a buzz and you now smoke, a gene may be to blame
Anyone who has ever tried smoking probably remembers that first cigarette vividly. For some, it brought a wave of nausea or a nasty coughing fit. For others, those first puffs also came with a rush of pleasure or "buzz." view more (2008-08-11)
'Smart' mice teach scientists about learning process, brain disorders
Mice genetically engineered to lack a single enzyme in their brains are more adept at learning than their normal cousins, and are quicker to figure out that their environment has changed, a team led by researchers at UT Southwestern Medical Center has found. view more (2007-05-29)
Decision-making impairment appears greater in alcoholics with coexisting personality disorders
People make decisions all the time: they form preferences, take action, and evaluate outcomes, whether rewarding or aversive. Impaired decision making is regarded as one of the neurobehavioral hallmarks of addiction. view more (2006-09-25)
Rat study suggests why teens get hooked on cocaine more easily than adults
New drug research suggests that teens may get addicted and relapse more easily than adults because developing brains are more powerfully motivated by drug-related cues. view more (2008-04-22)
Single-parent Children At Increased Risk Of Suicide, Psychiatric Disease, And Substance Abuse (pp 271, 289)
Authors of a Swedish population study in this week's issue of THE LANCET provide strong evidence that children brought up in single-parent households are more likely to suffer health problems--especially relating to mental illness and suicide risk--than children brought up with both parents in the same household. Research on the psychological and... view more... (2003-01-23)
New studies on cancer and schizophrenia, depression and heart disease, trauma and autism
The 2007 American College of Neuropsychopharmacology Annual Meeting will feature hundreds of new studies on brain and behavior from the world's leading scientists. Presentations include innovative research on potential new treatments for depression, post-traumatic stress disorder, autism and addiction. view more (2007-12-11)
Scripps Research scientists find seizure drug reverses cellular effects
In the new research, published in the May 28, 2008 edition of The Journal of Neuroscience, the scientists found that gabapentin normalizes the action of certain brain cells altered by chronic alcohol abuse in an area of the brain known as the central amygdala, which plays an important role in fear- and stress-related behaviors, as well as in... view more... (2008-05-29)
Stress-induced changes in brain circuitry linked to cocaine relapse
Stress-evoked changes in circuits that regulate serotonin in certain parts of the brain can precipitate a low mood and a relapse in cocaine-seeking, based on mouse studies published online this week in the Proceedings of the National Academy of Sciences. view more (2009-10-30)
Reanalysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent
A reanalysis of nicotine yield from major brand name cigarettes sold in Massachusetts from 1997 to 2005 has confirmed that manufacturers have steadily increased the levels of this agent in cigarettes. view more (2007-01-18)
Penn research probes genetic underpinnings of nicotine addiction
A new study from the Abramson Cancer Center and Department of Psychiatry in the University of Pennsylvania School of Medicine shows that smokers who carry a particular version of a gene for an enzyme that regulates dopamine in the brain may suffer from concentration problems and other cognitive deficits when abstaining from nicotine - a problem... view more... (2008-12-10)
A caring mother is a child's best defence against drug culture: European study shows
The barrier that 'good parents' can provide for their children against the drugs culture is beginning to break down in cities where drugs are most freely available, researchers have found. But the international study, led by Newcastle University in England, concluded that having a caring mother was the single most important factor in preventing... view more... (2002-05-09)
Addiction â€" You know you want to"¦ THE BIOCHEMIST October 2002 issue
The illicit manufacture of drugs It is estimated that around 180 million people around the world consume illicit drugs. The manufacture of these drugs is big business and depends on the regular supply of raw materials. Professor Hamid Ghodse (Chair of Addictive Behaviour, St George's Hospital Medical School) describes some of the International... view more... (2002-10-01)
Impact of narcotics is greater on mentally ill
Narcotics have an irreversible effect on the brains of people already suffering from mental illness. view more (2009-02-06)
Scripps team shows diet switching can activate brain's stress system, lead to 'withdrawal' symptoms
In research that sheds light on the perils of yo-yo dieting and repeated bouts of sugar-bingeing, researchers from The Scripps Research Institute have shown in animal models that cycling between periods of eating sweet and regular-tasting food can activate the brain's stress system and generate overeating, anxiety, and withdrawal-like symptoms. view more (2009-11-10)
Skin color clue to nicotine dependence
Higher concentrations of melanin -- the color pigment in skin and hair -- may be placing darker pigmented smokers at increased susceptibility to nicotine dependence and tobacco-related carcinogens than lighter skinned smokers, according to scientists. view more (2009-05-11)
PET imaging focuses on medication's purported ability to improve mental performance
Concerned by the growing numbers of people using stimulant medications such as methylphenidate (MP)-either legally or illegally-to improve attention and focus, researchers used positron emission tomography (PET) imaging with the radiotracer fluorodeoxyglucose (FDG) to assess the effects of the drug on brain function in the normal human brain. view more (2008-06-17)
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