Adenoviral Current Events | Adenoviral News
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Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells Pancreatic cancer is a devastating disease with poor prognosis. This warrants the development of novel therapies including gene therapy. view more (2009-06-24)
Study shows liver an excellent target for cancer gene therapy using viral vectors A featured paper in the February 14 issue of Nature Cancer Gene Therapy demonstrates that cancer cells in the liver are excellent targets for gene therapy using adenoviral vectors, based upon a fundamental new understanding of the differences between cancerous and normal liver cells. view more (2007-02-15)
New study shows that therapeutic gene expression can be sustainable for 1 year Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans. view more (2007-10-26)
Gamma globulin effective in treating eye infections caused by adenoviruses Gamma globulin, a type of antibody isolated from blood samples that used to be routinely given to health care workers and international travelers to protect them from infectious diseases, is a highly effective treatment for pinkeye with little apparent toxicity, according to a study by researchers at the University of Pittsburgh School of Medicine. view more (2007-08-29)
Saving salivary glands from the collateral damage of radiation therapy Researchers have shown that targeted overexpression of heat shock protein 25 prevents radiation-induced damage to salivary glands, a common consequence of treatment for head and neck cancer. view more (2006-10-30)
Blocking protein kills prostate cancer cells, inhibits tumor growth, Jefferson scientists find Researchers at Jefferson's Kimmel Cancer Center in Philadelphia have shown that they can effectively kill prostate cancer cells in both the laboratory and in experimental animal models by blocking a signaling protein that is key to the cancer's growth. view more (2008-02-28)
Yamanaka eliminates viral vector in stem cell reprogramming Shinya Yamanaka MD, PhD, of Kyoto University and the Gladstone Institute of Cardiovascular Disease (GICD) has taken another step forward in improving the possibilities for the practical application of induced pluripotent stem (iPS) cell technology. view more (2008-10-13)
Scientists shine new light on inflammatory diseases Investigators at Hospital for Special Surgery have identified a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis. view more (2008-03-17)
Abnormal overexpression of p53 is a predictive molecular biomarker A common laboratory test that predicted poor outcome from traditional radiation and chemotherapy treatment for head and neck cancers now has been found to predict a good prognosis with treatment of p53 tumor suppressor gene therapy-making it potentially the first predictive biomarker test for a gene-based drug. view more (2006-09-15)
ESC Congress 2003: Can we make a new sinus node? The promises of genetically engineered bio-pacemakers IMPORTANT: This press release accompanies both a presentation and an ESC press conference given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology Heart block is a condition in which the cardiac pacemaker impulse that is normally... view more... (2003-09-01)
Scientists identify novel way to prevent cardiac fibrosis In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body's pro-... view more... (2008-04-23)
Researchers engineer pancreatic cell transplants to evade immune response In a finding that could significantly influence the way type 1 diabetes is treated, researchers at Albert Einstein College of Medicine of Yeshiva University have developed a technique for transplanting insulin-producing pancreatic cells that causes only a minimal immune response in recipients. view more (2009-01-05)
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