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A molecular map for aging in mice
Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues.   view more (2007-11-29)

Reduced mitochondrial function important mechanism in aging
Scientists at the Karolinska Institute have found that changes in the "powerhouse" of cells, the mitochondria, play a key role in aging. The findings are being published in this week's issue of the journal Nature. Mitochondria, which provide energy to cells, have their own set of DNA. Mutations of mitochondrial DNA increase with age,... view more... (2004-05-27)

Secret of eternal youth may be in reptiles
Jo'£o Pedro Magalh'£es, researcher in the Biology of Aging, suggests, in work published in the June edition of the magazine "Experimental Gerontology" and entitled "The evolution of mammalian aging", that the study of certain species of reptiles and amphibians that apparently do not age could lead to discoveries about aging. For this... view more... (2002-06-18)

MicroRNA gene that regulates lifespan found by Yale scientists
Genes that control the timing of organ formation during development also control timing of aging and death, and provide evidence of a biological timing mechanism for aging, Yale researchers report in the journal Science.   view more (2005-12-23)

Retinol lotion reduces the fine wrinkles from natural aging of skin
Lotions containing retinol improve the appearance of skin that has become wrinkled through the normal aging process, not just skin that has been damaged by exposure to the sun.   view more (2007-05-22)

NIA uses Genomatix in stem cell research, suggests novel transcription factors for stemness
Genomatix Software with businesses in Munich, Germany and Ann Arbor, Michigan released today that the group of Kenneth R. Boheler at the National Institute on Aging, National Institutes of Health, Baltimore, Md published some remarkable work on embryonic stem (ES) cells.   view more (2008-03-04)

A First Glance at the Gene Networks of Human Aging
Boston, MA - July 29, 2004 - Scientists have rendered the first gene and protein networks of human aging, an important step in understanding the genetic mechanisms of aging. The work led by Joao Pedro de Magalhaes from Harvard Medical School is detailed in the July 30 issue of FEBS Letters.   view more (2004-07-29)

Lamin B locks up Oct-1
A large fraction of the transcription factor Oct-1 is associated with the inner nuclear envelope, but how and why it is retained there was unknown.   view more (2009-01-12)

Gene loss accelerates aging
Researchers have discovered that the loss of a gene called p63 accelerates aging in mice. Similar versions of the gene are present in many organisms, including humans. Therefore, the p63 gene is likely to play a fundamental biological role in aging-related processes.   view more (2005-08-17)

A new jump start for aging blood vessels
Recent studies show promise for significantly reducing vascular aging by inactivating TNFa, which has been linked to blood vessel dysfunction and cell death. The related report by Csiszar et al., "Vasculoprotective effects of anti-TNFa treatment in aging," appears in the January issue of The American Journal of Pathology.   view more (2006-12-28)

Researchers stress the need to educate consumers about hazards of tire aging
Human factors/ergonomics (HF/E) researchers at North Carolina State University have found that vehicle owners may not be aware that older but relatively unused tires can fail and cause crashes.   view more (2006-10-17)

Old before their time? Aging in flies under natural vs. laboratory conditions
Evolutionary studies of aging typically utilize small, short-lived animals (insects, worms, mice) under benign conditions - constant temperature and humidity, no parasites, superabundant food - in the laboratory. Oddly enough, very little is known about aging in such animals in their harsh, stressful natural environments. Could it be that these... view more... (2008-09-08)

New study shows successful aging a question of 'mind over matter'
A new study released at the American College of Neuropsychopharmacology's (ACNP) Annual Meeting suggests that the seniors' perceptions of the aging process depend not on disease or physical disability, but rather on attitude and coping style.   view more (2005-12-13)

World's Aging Population To Defuse War on Terrorism
Changing demographic trends will impact the future of international relations, according to the latest issue of Public Policy & Aging Report (PP&AR). Several hotbed areas in the world that offer the motive and opportunity for political violence are due to stabilize by the year 2030.   view more (2008-01-25)

Evolutionary conservation of a mechanism of longevity from worms to mammals
Though the study of aging in the nematode model organism C. elegans has provided much insight into this complex process, it is not yet clear whether genes involved in aging in the worm have a similar role in mammals.   view more (2005-10-05)

Topical retinol helps reduce wrinkles associated with natural skin aging
Applying vitamin A to the skin appears to improve the wrinkles associated with natural aging and may help to promote the production of skin-building compounds.   view more (2007-05-22)

Smoking associated with aging of nonfacial skin
A history of smoking may be associated with a higher degree of aging in skin not regularly exposed to light, such as that of the upper inner arm.   view more (2007-03-20)

How Fast You'll Age is Written in the Bones, TAU Research Finds
Perhaps the aging process can't be stopped. But it can be predicted, and new research from Tel Aviv University indicates that people may live longer and lead healthier lives as a result.   view more (2008-04-10)

Elderly immune system needs a boost
Elderly cancer patients need a combination of treatments tailor-made to their specific needs to successfully combat the disease.   view more (2009-10-09)

Sexual reproduction delays aging in a mammalian species
Past research on aging and the life histories of diverse species has shown that sexual reproduction is biologically costly for individuals and tends to decrease lifespan rather than increase it.   view more (2006-02-22)
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