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Brain DNA 'remodeled' in alcoholism
Reshaping of the DNA scaffolding that supports and controls the expression of genes in the brain may play a major role in the alcohol withdrawal symptoms, particularly anxiety, that make it so difficult for alcoholics to stop using alcohol.   view more (2008-04-02)

The dopamine transporter gene influences alcohol withdrawal seizures
The physiological component of alcoholism is defined by tolerance and/or withdrawal: the more severe the dependency on alcohol, the more severe the clinical complications, such as greater intensity and/or complications of alcohol withdrawal.   view more (2008-01-04)

Alcohol cravings and anxiety do not increase with repeat detoxification
People with alcohol problems have no greater anxiety or cravings after the second, third or fourth detoxification than the first, according to a new study by experimental psychologists at the University of Sussex. Previous studies have shown that the risk of seizures can increase with subsequent... view more (2002-06-14)

New research reveals the emotional costs of alcoholism
Alcoholics, especially those who relapse after frequent attempts to "dry out", are damaging areas of their brain that recognise emotions, a University of Sussex study suggests. Research on people's responses to photographs of different emotional facial expressions shows that heavy... view more (2002-03-01)

Alcoholism-treatment medication acamprosate may help abstinent alcoholics sleep better
Alcoholics generally don't sleep well. Nor does abstinence improve the situation much. In fact, sleep difficulties during alcohol abstinence may be responsible for a relapse to alcoholism as individuals attempt to self medicate their sleeping problems.   view more (2006-08-28)

New study reveals brain cell mechanism of alcohol dependence
A study released today reveals a cellular mechanism involved in alcohol dependence. The study, in the May 28 issue of The Journal of Neuroscience, shows that gabapentin, a drug used to treat chronic pain and epilepsy, reduces alcohol intake in alcohol-dependent rats by normalizing chemical... view more (2008-05-29)

Disrupting brain's stress system intensifies opiate withdrawal
Avoiding the severe pain, nausea, agitation, sweats and other symptoms of opiate withdrawal are among the many reasons addicts are motivated to continue taking drugs.   view more (2007-02-15)

Study links effects of withdrawal to compulsive drug use and craving
The study, led by Paul Kenny, Ph.D., an assistant professor at Scripps Research's campus in Jupiter, Florida, and Scott Chen, Ph.D., of the National Institutes of Health Animal Center, appears in the Wednesday, May 31 issue of the Journal of Neuroscience, the official journal of the Society for... view more (2006-06-02)

Alcohol and high-risk sexual behaviors in Botswana
Heavy alcohol consumption is strongly and consistently associated with sexual risk behaviors in both men and women in Botswana, according to one of the few research studies on the topic in sub-Saharan Africa.   view more (2006-10-10)

Fatigue is an important factor in serious road crashes
Fatigue, especially when combined with alcohol, presents a particularly high risk of road crashes resulting in death or serious injury, finds a study in this week's BMJ. Data from the French Ministry of Transport was used to investigate the role of fatigue in serious, single-vehicle crashes during... view more (2001-04-03)

Intensive-care patients with alcohol problems are more likely to require mechanical ventilation
More than 300,000 patients receive mechanical ventilation during intensive care per year in the United States, even though the hospital mortality rate for ventilated patients can approach 50 percent.   view more (2007-06-26)

Alcoholism Is A Major, Neglected Problem In Patients With Heart Disease.
Some epidemiological studies suggest that moderate alcohol consumption decreases the risk of coronary heart disease. However, long-term excessive alcohol drinking is considered to be a major cause for worsening of heart disease. A group of Greek investigators, headed by George Christodoulou,... view more (2000-12-28)

Drinking Alcohol Increases Risk for Cancer
Drinking Alcohol Increases Risk for Cancer   view more (2005-01-31)

UCLA researchers discover how drug binds to neurons to stop drunken symptoms of alcohol
UCLA researchers discovered how an experimental drug, called Ro15-4513, binds to specific receptors on brain neurons, which helps explain how this drug stops the drunken behavioral symptoms of alcohol such as impaired motor coordination, memory loss and drowsiness.   view more (2006-05-09)

Early drinking linked to risk for alcohol dependence
Individuals who are younger when they begin drinking alcohol may face a higher risk of alcohol dependence throughout life, at a younger age and consisting of multiple episodes.   view more (2006-07-05)

New compound prevents alcoholic behavior, relapse in animals by blocking stress response
A study of alcohol-dependent animals shows that a newly discovered compound that blocks chemical signals active during the brain's response to stress effectively stops excessive drinking and prevents relapse.   view more (2007-03-07)

Scripps Research scientists find seizure drug reverses cellular effects
In the new research, published in the May 28, 2008 edition of The Journal of Neuroscience, the scientists found that gabapentin normalizes the action of certain brain cells altered by chronic alcohol abuse in an area of the brain known as the central amygdala, which plays an important role in fear-... view more (2008-05-29)

Researchers find nicotine withdrawal begins quickly
Smokers who have tried to quit are well aware of the symptoms of nicotine withdrawal: cravings for cigarettes, mood disturbances, appetite increase and sleep problems.   view more (2006-08-22)

The glutamate decarboxylase 1 gene may play a pivotal role in developing alcoholism
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. GABA has been implicated in the development of alcoholism, although the mechanisms through which this occurs are unclear.   view more (2006-10-25)

Do we need alcohol prevention programs for 'tweens?'
The article examined a large study of six grade students across a metropolitan area, to see which factors distinguished young alcohol users from nonusers, including even their stated intentions regarding future alcohol use.   view more (2008-04-03)

Chronic Alcohol Exposure Can Affect Brain Protein Expression
Researchers at the University at Buffalo studying the effects of alcohol on the brain, using zebrafish as a model, have identified several novel central nervous system proteins that are affected by chronic alcohol exposure.   view more (2006-08-30)

A short walk helps smokers quit
Smokers should do short bouts of exercise to help them resist the temptation to light up, say experts at the University of Exeter.   view more (2007-03-14)

Moderate alcohol consumption enhances the formation of new nerve cells - may contribute to alcohol dependency
Moderate alcohol consumption over a relatively long period of time can enhance the formation of new nerve cells in the adult brain. The new cells could prove important in the development of alcohol dependency and other long-term effects of alcohol on the brain. The findings are published by... view more (2005-04-26)

Risk threshold of daily alcohol intake and drinking duration in liver injury?
Alcoholic threshold effect rather than a dose-response effect on mortality from alcohol-related liver injury. Alcohol intake, rather than the type of alcoholic beverage, was more significant to liver injury.   view more (2008-05-21)

Marijuana withdrawal as bad as withdrawal from cigarettes
Research by a group of scientists studying the effects of heavy marijuana use suggests that withdrawal from the use of marijuana is similar to what is experienced by people when they quit smoking cigarettes.   view more (2008-01-25)

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