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Chemical signature of manic depression discovered by scientists
People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published today in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause.   view more (2008-02-06)

Arginine discovery could help fight human obesity
A Texas AgriLife Research scientist and fellow researchers have discovered that arginine, an amino acid, reduces fat mass in diet-induced obese rats and could help fight human obesity.   view more (2009-02-05)

Pitt researchers describe molecular '2-step' leading to protein clumps of Huntington's disease
In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that might lead to the formation of pathogenic protein clumps in Huntington's disease, and possibly other movement-related... view more... (2009-03-09)

Enzyme discovery sheds light on vitamin D
Surprising findings by Queen's researchers have shed new light on how the "sunshine vitamin" D - increasingly used to treat and prevent cancer and other diseases - is broken down by our bodies.   view more (2007-07-25)

UC Davis researchers discover Achilles' heel in pancreatic cancer
UC Davis Cancer Center researchers have discovered a metabolic deficiency in pancreatic cancer cells that can be used to slow the progress of the deadliest of all cancers.   view more (2008-11-07)

The sweet science: Viruses switch grip to gain upper hand
Carbohydrates can be attractive, especially when they come packaged in candy bars or never-ending bowls of pasta.   view more (2006-09-14)

Link possible between pet food contamination and baby formula contamination
A study published in the November issue of a scientific journal, Toxicological Sciences, which is published by Oxford Journals on behalf of the Society of Toxicology, describes the kidney toxicity of melamine and cyanuric acid based on research that was done to characterize the toxicity of the compounds that contaminated pet food in North America... view more... (2008-10-16)

Scientists map steps to block key enzyme action in heart failure
Taking a cue from the way drugs like Viagra put the biological brakes on a key enzyme involved in heart failure, scientists at Johns Hopkins have mapped out a key chemical step involved in blocking the enzyme.   view more (2008-11-12)

Massage after exercise myth busted by Queen's research team
A Queen's University research team has blown open the myth that massage after exercise improves circulation to the muscle and assists in the removal of lactic acid and other waste products.   view more (2009-05-08)

UIC researchers show how cancer-preventing foods work
Researchers at the University of Illinois at Chicago are unraveling the biochemical mechanism by which functional foods combat cancer.   view more (2005-07-11)

Are certain congenital birth defects and heart disease linked?
The study implicates homocysteine, a chemical by-product of human metabolism. Homocysteine is particularly important for cell growth and is regulated by enzymes, the activities of which are partly genetically determined, and partly affected by diet, including the levels of vitamins B6, B12, and folic acid in the blood.   view more (1999-11-15)

Not enough 'good' cholesterol makes it harder to recover from stroke
People are at an increased risk of memory problems and greater disability after stroke if they have low levels of "good" cholesterol and high levels of homocysteine, an amino acid acquired mostly from eating meat.   view more (2007-11-27)

Serum bile acid profiling for inflammatory bowel disease characterization
Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC.   view more (2009-07-16)

Protein's essential role in repairing damaged cells revealed
University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.   view more (2009-01-07)

Proteins by Design: Penn Biochemists Create New Protein from Scratch
No doubt proteins are complex. Most are "large" and full of interdependent branches, pockets and bends in their final folded structure. This complexity frustrates biochemists and protein engineers seeking to understand protein structure and function in order to reproduce or create new uses for these natural molecules to fight diseases or... view more... (2009-03-24)

Comprehensive model is first to map protein folding at atomic level
Scientists at Harvard University have developed a computer model that, for the first time, can fully map and predict how small proteins fold into three-dimensional, biologically active shapes.   view more (2006-11-07)

Glutamine supplements show promise in treating stomach ulcers
Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers.   view more (2009-05-18)

Molecular evolution of influenza A viruses circulated in Fujian Province, China
Fujian Center for Disease Control & Prevention, China, reported the molecular evolution of influenza A (H3N2) viruses in Fujian Province, south of China during the period 1996 - 2004 and demonstrated some key codons responsible for antigenic drift. The study is reported in Issue 51 (April, 2008) of the Science in China Series C: Life Science... view more... (2008-04-01)

High doses of folic acid may help to prevent stomach cancer
High doses of folic acid may help to prevent digestive tract cancers, suggests animal research reported in Gut.   view more (2001-12-17)

A safe folic acid boost from flour
Public consumption of folic acid from fortified flour at current mandated US levels (100micro-gram/day) and at double this amount is probably safe, at average intakes, according to an article published today in the open access journal BMC Public Health.   view more (2007-03-22)
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