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Amino Acid Current Events | Amino Acid News | 9

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Bacterial protein mimics host to cripple defenses
Like a wolf in sheep's clothing, a protein from a disease-causing bacterium slips into plant cells and imitates a key host protein in order to cripple the plant's defenses.   view more (2005-12-23)

Use of acid-suppressive medications associated with increased risk of hospital-acquired pneumonia
Hospitalized patients who receive acid-suppressive medications such as a proton-pump inhibitor have a 30 percent increased odds of developing pneumonia while in the hospital.   view more (2009-05-27)

Adding folic acid to flour significantly reduces congenital malformations
Dr. Philippe De Wals of Université Laval's Department of Social and Preventive Medicine today publishes a study clearly indicating that the addition of folic acid to flours has led to a 46% drop in the incidence of congenital neural tube deformation (mainly anencephaly and spina bifida) in Canada.   view more (2007-07-13)

Impact of elevated homocysteine levels on vision under study
Homocysteine, an amino acid believed to contribute to heart attack, stroke and dementia, likely also is a player in retinal damage and vision loss, researchers say.   view more (2007-10-16)

European folic acid policies are not effective enough
The prevalence of neural tube defects in Europe has not declined substantially in the past decade, despite national policies of folic acid supplementation in half the countries, finds a study in this week's BMJ.   view more (2005-03-09)

Gains in the fight against acid aspiration lung injury
Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.   view more (2006-05-03)

Rebuilding the evolutionary history of HIV-1 unravels a complex loop
An essential component of the human immunodeficiency virus (HIV-1) molecular machinery responsible for infecting cells consists of functionally-specialized layers, according to a study by investigators at the University of California San Diego (UCSD) Antiviral Research Center (AVRC), published November 23 in PLoS Computational Biology.   view more (2007-11-26)

Folic acid supplementation does not appear to reduce risk of cardiovascular diseases
An analysis of previous studies suggests that for people with a history of vascular disease, folic acid supplementation does not decrease the risk of coronary heart disease or stroke, as has been suggested in some research.   view more (2006-12-13)

Leprosy, tuberculosis, and peanuts
Nitric oxide is a natural part of the body’s immune defense. Linköping University researcher Thomas Schön has studied this compound in connection with the skin disease leprosy and the lung disease tuberculosis. The Swedish researcher has found that nitric oxide probably contributes to the disease in the case of leprosy but, on the... view more... (2002-11-01)

Acetaminophen or acetylsalicylic acid increases risk of developing chronic kidney failure
People who regularly use high dosages of pain-relievers or antipyretic drugs containing acetaminophen (paracetamol) or acetylsalicylic acid run an increased risk of developing permanent reduced kidney function (chronic renal failure). This was found in a nation-wide Swedish research study published on December 20 in The New England Journal of... view more... (2001-12-21)

Potential Alzheimer's disease drug target identified by UC San Diego researcher
In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease.   view more (2008-03-17)

Combination treatment enhances tetanus vaccination
In studies with mice, Penn State researchers have shown that a combination of retinoic acid - a product the body makes naturally from vitamin A - and PIC, a synthetic immunity booster, significantly elevates the immune system response to a tetanus shot.   view more (2005-09-13)

Free-energy theory borne out in large-scale protein folding
In unprecedented new research, scientists at Rice University have combined theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein.   view more (2005-10-04)

SCIENTISTS TAKE A STEP CLOSER TO UNDERSTANDING BREAST CANCER GENEWorld first for Imperial Cancer Research Fund
Scientists from the Imperial Cancer Research Fund are the first in the world to solve the structure of an important region of a protein molecule made by the XRCC1 gene which has a role in human DNA repair. The same region is also found in the BRCA1 gene which is involved in breast cancer. Their findings now explain why some genetic changes can... view more... (1998-11-03)

Naked turkey
WHAT`S the secret of great-tasting Christmas turkey? Let it get naked. Whipping the foil off a cooking turkey to allow the skin to brown induces a previously unrecognised process that concentrates the meat flavours at the surface. Chefs have always known that browning the bird with direct heat creates flavour. But more important than the heat,... view more... (2001-12-19)

Detailed 3-D image catches a key regulator of neural stem cell differentiation in action
Researchers at the Salk Institute for Biological Studies in collaboration with scientists at the University of California, San Diego (UCSD) took a high resolution "action shot" of a protein switch that plays a crucial role in the development of the nervous system.   view more (2006-12-08)

Loss of a universal tRNA feature reported
Scientists at the Virginia Bioinformatics Institute (VBI) report in the Journal of Bacteriology that two alphaproteobacteria lack the universal extra guanylate nucleotide typically found in the transfer RNA molecule tRNAHis. tRNAs are the molecules responsible for decoding sequence information specified by messenger RNA molecules, information... view more... (2007-02-08)

Fat overrides effects of vitamin C
Fats in our stomach may reduce the protective effects of antioxidants such as vitamin C. Scientists at the University of Glasgow found that in the presence of lipid the ability of antioxidants, such as ascorbic acid (the active component of vitamin C), to protect against the generation of potential cancer-forming compounds in the stomach is less... view more... (2007-04-02)

Swine flu genes dissimilar to past pandemics
Some genetic markers of influenza infection severity have been identified from past outbreaks. Researchers have failed to find most of these markers, described in the open access journal BMC Microbiology, in samples of the current swine-flu strain.   view more (2009-05-07)

Weizmann Institute scientists develop a general 'control switch' for protein activity
Our bodies could not maintain their existence without thousands of proteins performing myriad vital tasks within cells. Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders.   view more (2007-06-20)
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