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Amino Acid Current Events | Amino Acid News | 9
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Pathogen virulence proteins suppress plant immunity
Researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech and their colleagues have identified a key function of a large family of virulence proteins that play an important role in the production of infectious disease by the plant pathogen Phytophthora sojae. view more (2008-04-22)
Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
News brief: Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute. view more (2009-10-13)
Fortifying food with folic acid benefits babies
Adding folic acid to food can dramatically reduce the incidence of spina bifida and other birth defects. A study, published today in BMC Pregnancy and Childbirth, shows that the proportion of babies born with neural tube defects in the province of Newfoundland and Labrador dropped by 78% after the Canadian Government directed that folic acid must... view more... (2004-09-23)
Folding Proteins on a Computer
Proteins only function when properly folded In order for enzymatic reactions to proceed correctly, the enzyme and substrate must fit together as precisely as a lock and key. The function of the enzyme and protein is determined by the structure of the latter. The chain of amino acids that makes up the protein thus has to fold in a very precise... view more... (2001-01-19)
Alzheimer's discovery could bring early diagnosis, treatment closer
A discovery made by researchers at McGill University and the affiliated Lady Davis Research Institute for Medical Research at Montreal's Jewish General Hospital offers new hope for the early diagnosis and treatment of Alzheimer's disease. view more (2009-05-26)
Bacterial protein mimics host to cripple defenses
Like a wolf in sheep's clothing, a protein from a disease-causing bacterium slips into plant cells and imitates a key host protein in order to cripple the plant's defenses. view more (2005-12-23)
Use of acid-suppressive medications associated with increased risk of hospital-acquired pneumonia
Hospitalized patients who receive acid-suppressive medications such as a proton-pump inhibitor have a 30 percent increased odds of developing pneumonia while in the hospital. view more (2009-05-27)
Adding folic acid to flour significantly reduces congenital malformations
Dr. Philippe De Wals of Université Laval's Department of Social and Preventive Medicine today publishes a study clearly indicating that the addition of folic acid to flours has led to a 46% drop in the incidence of congenital neural tube deformation (mainly anencephaly and spina bifida) in Canada. view more (2007-07-13)
Impact of elevated homocysteine levels on vision under study
Homocysteine, an amino acid believed to contribute to heart attack, stroke and dementia, likely also is a player in retinal damage and vision loss, researchers say. view more (2007-10-16)
European folic acid policies are not effective enough
The prevalence of neural tube defects in Europe has not declined substantially in the past decade, despite national policies of folic acid supplementation in half the countries, finds a study in this week's BMJ. view more (2005-03-09)
Gains in the fight against acid aspiration lung injury
Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary. view more (2006-05-03)
Folic acid supplementation does not appear to reduce risk of cardiovascular diseases
An analysis of previous studies suggests that for people with a history of vascular disease, folic acid supplementation does not decrease the risk of coronary heart disease or stroke, as has been suggested in some research. view more (2006-12-13)
Rebuilding the evolutionary history of HIV-1 unravels a complex loop
An essential component of the human immunodeficiency virus (HIV-1) molecular machinery responsible for infecting cells consists of functionally-specialized layers, according to a study by investigators at the University of California San Diego (UCSD) Antiviral Research Center (AVRC), published November 23 in PLoS Computational Biology. view more (2007-11-26)
Leprosy, tuberculosis, and peanuts
Nitric oxide is a natural part of the body’s immune defense. Linköping University researcher Thomas Schön has studied this compound in connection with the skin disease leprosy and the lung disease tuberculosis. The Swedish researcher has found that nitric oxide probably contributes to the disease in the case of leprosy but, on the... view more... (2002-11-01)
Acetaminophen or acetylsalicylic acid increases risk of developing chronic kidney failure
People who regularly use high dosages of pain-relievers or antipyretic drugs containing acetaminophen (paracetamol) or acetylsalicylic acid run an increased risk of developing permanent reduced kidney function (chronic renal failure). This was found in a nation-wide Swedish research study published on December 20 in The New England Journal of... view more... (2001-12-21)
Potential Alzheimer's disease drug target identified by UC San Diego researcher
In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease. view more (2008-03-17)
Combination treatment enhances tetanus vaccination
In studies with mice, Penn State researchers have shown that a combination of retinoic acid - a product the body makes naturally from vitamin A - and PIC, a synthetic immunity booster, significantly elevates the immune system response to a tetanus shot. view more (2005-09-13)
SCIENTISTS TAKE A STEP CLOSER TO UNDERSTANDING BREAST CANCER GENEWorld first for Imperial Cancer Research Fund
Scientists from the Imperial Cancer Research Fund are the first in the world to solve the structure of an important region of a protein molecule made by the XRCC1 gene which has a role in human DNA repair. The same region is also found in the BRCA1 gene which is involved in breast cancer. Their findings now explain why some genetic changes can... view more... (1998-11-03)
Free-energy theory borne out in large-scale protein folding
In unprecedented new research, scientists at Rice University have combined theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein. view more (2005-10-04)
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