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New study finds amniocentesis safer for pregnant women
Amniocentesis is the most commonly prescribed invasive test performed during pregnancies in the United States.   view more (2006-11-01)

Study shows prenatal diagnostic tests have low risk of miscarriage
Pregnant women who seek prenatal diagnostic testing to identify genetic or chromosomal abnormalities have a lower risk of miscarriage than previously believed, according to a UCSF study.   view more (2006-09-01)

MRS shows promise as noninvasive means to determine fetal lung maturity
MR spectroscopy (MRS) of choline levels shows promise as a marker of fetal lung maturity, according to a recent study conducted by researchers at the University of California-San Francisco.   view more (2007-05-07)

'QUADRUPLE TEST' OFFERS BEST PREDICTION FOR DOWN'S SYNDROME (pp 794, 835)
Authors of a research letter in this week's issue of THE LANCET highlight how screening for Down's syndrome based on maternal age and four markers in maternal blood should be used worldwide-the quadruple test is far more effective than screening based on maternal age alone. Screening for Down's syndrome is widely practised early in the second... view more... (2003-03-05)

Study calls for end to age thresholds for prenatal genetic testing (pp 258, 276)
US research in this week's issue of THE LANCET challenges the health policies common in many countries in relation to maternal age and prenatal testing for chromosomal abnormalities such as Down's syndrome. Authors of the research conclude that current evidence does not support the conventional view that the balance between health risks and cost... view more... (2004-01-21)

New screening methods for Down`s syndrome questioned
New screening techniques for Down`s syndrome are less effective than previously supposed, despite a government initiative to offer all pregnant women the new tests by 2004, finds a study in this week`s BMJ.   view more (2002-07-03)

Ultrasound Detection of Down Syndrome
New Method Shown to be Effective for Detecting Down Syndrome at Mid-Trimester Scan Looking at the nasal bones of fetuses at the mid-trimester scan could improve the detection of Down Syndrome during pregnancy, according to results to be published in the January 2003 issue of Ultrasound in Obstetrics & Gynecology, the official journal of the... view more... (2002-12-12)

Best antenatal screening: study results
A study of about 50,000 pregnant women has shown that the integrated test for Down's syndrome offers a "significantly higher" level of safety than the screening available to most women in the UK. The study, which will be reported in the June Journal of Medical Screening, was carried out by Professor Nicholas Wald and colleagues at the... view more... (2003-06-02)

New data supports a non-invasive approach to routine prenatal genetic testing
Research studies demonstrating the viability of an approach to routinely detect the presence of fetal DNA in a mother's blood to accurately diagnose or rule out genetic defects — as early as the first trimester — was presented today at the 27th Annual Meeting of the Society for Maternal-Fetal Medicine being held in San Francisco.   view more (2007-02-12)

Toward a faster prenatal test for Down syndrome
Scientists in California are reporting an advance toward rapid testing for pre-natal detection of Down syndrome and other birth defects that involve an abnormal number of chromosomes.   view more (2007-09-19)

New blood test for Down syndrome
Howard Hughes Medical Institute researchers have developed a new prenatal blood test that accurately detected Down syndrome and two other serious chromosomal defects in a small study of 18 pregnant women.   view more (2008-10-07)

Microarray analysis improves prenatal diagnosis
A "chip" or array that can quickly detect disorders such as Down syndrome or other diseases associated with chromosomal abnormalities proved an effective tool in prenatal diagnosis in a series of 300 cases at Baylor College of Medicine, said researchers in a report that appears in the current issue of the journal Prenatal Diagnosis.   view more (2008-11-18)

Cells from amniotic fluid used to tissue-engineer a new trachea
Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.   view more (2005-10-10)

Prematurity more accurately predicted by advances in proteomic technology
Abnormal proteins in amniotic fluid that signal a higher risk of delivering prematurely are being detected with increasing accuracy by Yale School of Medicine researchers who presented their work in two abstracts at the Society for Maternal-Fetal Medicine Conference February 8 in San Francisco.   view more (2007-02-09)

Noninvasive screening in early pregnancy reduces Down's births by 50 percent
Non-invasive screening of pregnant women with ultrasound early in pregnancy, combined with maternal blood analysis, has reduced the number of children born in Denmark with Down Syndrome by 50%.   view more (2007-06-18)

New screening halves the number of children born with Down syndrome
A new national screening strategy in Denmark has halved the number of infants born with Down's syndrome and increased the number of infants diagnosed before birth by 30%, according to a study published on bmj.com today.   view more (2008-12-01)

Scientists find potential stem cells in amniotic fluid - a new source?
Research by Austrian geneticists has raised the possibility that stem cells[1] could be isolated from amniotic fluid - the protective 'bath water' that surrounds the unborn baby. Geneticist Professor Markus Hengstschl'¤ger and his team at the University of Vienna have isolated a subgroup of cells from amniotic fluid that express a protein called... view more... (2003-06-27)

Understanding the implications of prenatal testing for Down syndrome
New article examines the influence of current tests on birth rates, assesses forthcoming tests, and calls for the establishment of medical and educational policies.   view more (2009-09-14)

UCLA researchers examine human embryonic stem cell genome
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.   view more (2008-03-28)

Profiling amniotic fluid yields faster test for infection and preterm birth risk, researchers find
Researchers at the 26th Annual Society for Maternal-Fetal Medicine (SMFM) meeting today announced that profiling certain proteins in amniotic fluid is the fastest and most accurate way to detect potentially dangerous infections in pregnant women.   view more (2006-02-02)
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