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Alzheimer's disease prevention may be easier than cure
Current hypotheses suggest that it is the accumulation over time of amyloid beta peptide 1-42 (Abeta42) that triggers changes in the brain that lead to cognitive dysfunction in Alzheimer's disease.   view more (2005-12-09)

Researchers discover a new genetic cause of Alzheimer's disease
Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are the first to show that the quantity of amyloid protein in brain cells is a major risk factor for Alzheimer's disease.   view more (2006-04-20)

Scientists isolate chemical in curry that may help immune system clear plaques found in Alzheimer's
Researchers isolated bisdemethoxycurcumin, the active ingredient of curcuminoids - a natural substance found in turmeric root - that may help boost the immune system in clearing amyloid beta, a peptide that forms the plaques found in Alzheimer's disease.   view more (2007-07-17)

Anesthesia and Alzheimer's
In studies of human brain cells, the widely-used anesthetic desflurane does not contribute to increased production of amyloid-beta protein; however, when combined with low oxygen conditions, it can produce more of this Alzheimer's associated protein.   view more (2008-04-28)

Anti-inflammatory drug blocks brain plaques
Brain destruction in Alzheimer's disease is caused by the build-up of a protein called amyloid beta in the brain, which triggers damaging inflammation and the destruction of nerve cells.   view more (2008-06-24)

Alzheimer's study first to explain death of brain cells
Researchers at Children's Hospital & Research Center at Oakland (CHRCO) have published a new study that is the first to explain how brain cells die in patients with Alzheimer's Disease.   view more (2006-03-15)

Gladstone researchers identify new drug target for Alzheimer's disease
Researchers at the Gladstone Institute of Neurological Disease have identified a potential new way to stop brain cell death related to Alzheimer's disease.   view more (2005-12-02)

Researchers get closer to preventing Alzheimer's disease
A recent study directed by Mount Sinai School of Medicine identifies a faulty molecule in the brain found in cases of mild cognitive impairment (MCI).   view more (2006-07-06)

Short sugar chains--­a future drug for Alzheimer's?
Heparansulfate, which is needed for normal fetal development among other things, is also important for the build-up of amyloid, morbid protein deposits that appear in several serious diseases. This is shown by Uppsala scientists in an article published in today's Net edition of the U.S. journal... view more (2005-04-19)

A molecular basis for selective therapeutic intervention in Alzheimer's disease
Alzheimer's disease, a complex neurological disorder, has as one of its hallmarks the presence of senile plaques in the brains of affected individuals.   view more (2005-10-07)

QBI neuroscientists make Alzheimer's disease advance
Queensland Brain Institute (QBI) neuroscientists at UQ have discovered a new way to reduce neuronal loss in the brain of a person with Alzheimer's disease.   view more (2008-06-10)

Enzyme shreds Alzheimer's protein
An enzyme found naturally in the brain snips apart the protein that forms the sludge called amyloid plaque that is one of the hallmarks of Alzheimer's disease (AD), researchers have found.   view more (2006-09-21)

Researchers close in on origins of main ingredient of Alzheimer's plaques
The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned.   view more (2008-04-10)

Different forms of amyloid beta in Alzheimer's disease harm neurons in different ways
Researchers at UC Irvine have shown that different forms of amyloid beta lead to neural damage in different ways, leading to an increasingly complex view of amyloid toxicity in the Alzheimer brain.   view more (2006-06-01)

Can tomatoes carry the cure for Alzheimer's?
The humble tomato could be a suitable carrier for an oral vaccine against Alzheimer's disease, according to HyunSoon Kim from the Korea Research Institute of Bioscience and Biotechnology (KRIBB) in Korea and colleagues from Digital Biotech Inc. and the Department of Biological Science at Wonkwang... view more (2008-07-09)

PET scans may help assess presence of brain plaques related to Alzheimer's disease
A type of positron emission tomography (PET) scanning may be useful in a non-invasive assessment of the formation of Alzheimer's disease-related plaques in the brain, according to small study posted online today that will appear in the October 2008 print issue of Archives of Neurology, one of the... view more (2008-08-12)

Receptor critical in neurodegeneration reduces Alzheimer's plaque
Increasing the level of a protein that plays a key role in traumatic spinal cord injuries and multiple sclerosis reduces the concentration of disease-causing plaque in Alzheimer's disease.   view more (2006-02-03)

Draining away brain's toxic protein to stop Alzheimer's
Scientists are trying a plumber's approach to rid the brain of the amyloid buildup that plagues Alzheimer's patients: Simply drain the toxic protein away.   view more (2007-08-13)

Chemical found in curry may help immune system clear amyloid plaques found in Alzheimer's disease
UCLA/VA researchers found that curcumin - a chemical found in curry and turmeric - may help the immune system clear the brain of amyloid beta, which form the plaques found in Alzheimer's disease.   view more (2006-10-04)

The immune system and Alzheimer's disease
Utrecht researchers, funded by NWO, have determined the role played by brain cells from the immune system that are located close to dying memory cells. The research will help determine the causes of Alzheimer's disease. In patients with Alzheimer's disease, the brain cells die off. The death of... view more (2001-11-27)

Purdue findings reveal possible Alzheimer's link to brain organ
Researchers have discovered that an organ in the brain called the choroid plexus apparently plays a critical role in preventing the accumulation of a protein associated with Alzheimer's disease.   view more (2006-03-22)

UIC chemists characterize Alzheimer's neurotoxin structure
Amyloid plaques, the hallmark of Alzheimer's disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease.   view more (2007-12-04)

Study validates Pittsburgh Compound-B in identifying Alzheimer's disease brain toxins
A groundbreaking study conducted by University of Pittsburgh Alzheimer's disease researchers reported in the journal Brain (currently online) confirms that Pittsburgh Compound-B (PiB) binds to the telltale beta-amyloid deposits found in the brains of patients with Alzheimer's disease.   view more (2008-03-27)

Blocking immune cell action increases Alzheimer's-associated protein deposits
The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder.   view more (2007-03-28)

Researchers find mutiple proteins that stick to medical devices
Biomedical engineers at Washington University in St. Louis have found a new role for the blood protein serum amyloid P in the body's response to medical materials, which may help to explain a variety of problems associated with heart-lung bypass, hemodialysis and the use of artificial vascular... view more (2005-10-06)

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