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Potential Alzheimer's disease drug target identified by UC San Diego researcher
In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease. view more (2008-03-17)
Naturally occurring enzyme can break down key part of Alzheimer's plaques
Scientists have identified a naturally occurring enzyme that can break down a key component of the brain plaques characteristic of Alzheimer's disease. view more (2006-10-25)
A Sweet Solution to Alzheimer's Disease?
Certain variants of a simple sugar ameliorate Alzheimer's-like disease in mice, according to a new study by Canadian researchers. view more (2006-06-14)
New clues to amyloidoses ?
Familial amyloid polyneuropathy (FAP), a hereditary disease characterised by abnormal deposits of insoluble protein in the organs, results from a mutation in a single gene (the transthyretin or TTR gene). Nevertheless, disease incidence and age of onset can vary significantly between patients what have always puzzled scientists. Now, in the latest... view more... (2005-02-18)
Zeroing in on Alzheimer's
Hereditary Alzheimer's disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer's are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q, which contains more than 100 genes. Working with... view more... (2003-09-25)
Keeping amyloid-and Alzheimer's-in check
Researchers have identified a protein that reins in the rogue activity of the molecules that make the amyloid-beta protein-which may prevent normal brain function in people with Alzheimer's disease. view more (2006-04-27)
A 'grape' future for Alzheimer's disease research
With National Alzheimer's Awareness Month upon us, attention continues to focus on new approaches to cognitive health in an aging population. view more (2007-11-07)
New method to stimulate immune system may be effective at reducing amyloid burden in Alzheimer's
Researchers at NYU Langone Medical Center have discovered a novel way to stimulate the innate immune system of mice with Alzheimer's disease (AD) - leading to reduced amyloid deposits and the prevention of Alzheimer's disease related pathology - without causing toxic side effects. view more (2009-02-12)
Role of anesthetics in Alzheimer's disease: Molecular details revealed
Inhaled anesthetics commonly used in surgery are more likely to cause the aggregation of Alzheimer's disease-related plaques in the brain than intravenous anesthetics. view more (2007-01-29)
Umbilical cord blood cell therapy in an animal model of Alzheimer's disease
A novel strategy based on targeted immune suppression using human umbilical cord blood cells may improve the pathology and cognitive decline associated with Alzheimer's disease. view more (2008-03-27)
Two cardiovascular proteins pose a double whammy in Alzheimer's
Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease. view more (2008-12-22)
Genetic variation may reduce Alzheimer's risk
Adults with a genetic variation enabling them to express higher levels of fetal hemoglobin may have a reduced risk of Alzheimer's disease, researchers say. view more (2007-01-09)
A high fat, low carbohydrate diet improves Alzheimer's disease in mice
Mice with the mouse model of Alzheimer's disease show improvements in their condition when treated with a high-fat, low-carbohydrate diet. view more (2005-10-17)
Scripps research study reveals structural dynamics of single prion molecules
New techniques paint clearer picture of amyloid formation associated with protein-based inheritance and neurodegenerative diseases such as mad cow, Alzheimer's. view more (2007-02-13)
Green tea ingredient prevents Alzheimer's-like brain damage in mice
Researchers at the University of South (USF) have found that green tea may offer another potential health benefit - protecting the brain against the ravages of Alzheimer's disease. view more (2005-09-21)
Tiny but toxic: MBL researchers discover a mechanism of neurodegeneration in Alzheimer's disease
Tiny, toxic protein particles severely disrupt neurotransmission and inhibit delivery of key proteins in Alzheimer's disease, two separate studies by Marine Biological Laboratory (MBL) researchers have found. view more (2009-03-27)
Anti-hypertensive drugs may help prevent and treat Alzheimer's disease
A new study has identified commonly prescribed drugs for the treatment of hypertension may be capable of preventing Alzheimer�s disease and cognitive deterioration. view more (2007-10-26)
Scientists find new genetic clue to cause of Alzheimer's disease
Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's, is reported in Nature Genetics online, Jan. 14, 2007, and was supported in part by the National... view more... (2007-01-15)
Salk study links diabetes and Alzheimer's disease
Diabetic individuals have a significantly higher risk of developing Alzheimer's disease but the molecular connection between the two remains unexplained. Now, researchers at the Salk Institute for Biological Studies identified the probable molecular basis for the diabetes - Alzheimer's interaction. view more (2008-05-01)
Study indicates grape seed extract may reduce cognitive decline associated with Alzheimer's disease
A compound found in grape seed extract reduces plaque formation and resulting cognitive impairment in an animal model of Alzheimer's disease, new research shows. The study appears in the June 18 issue of The Journal of Neuroscience. view more (2008-06-18)
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