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Draining away brain's toxic protein to stop Alzheimer's
Scientists are trying a plumber's approach to rid the brain of the amyloid buildup that plagues Alzheimer's patients: Simply drain the toxic protein away.   view more (2007-08-13)

University Hospitals Case Medical Center to test gammaglobulin treatment for Alzheimer's disease
Researchers from the Memory and Cognition Center at University Hospitals Case Medical Center will begin testing an intriguing new approach to slowing down the progression of Alzheimer's Disease (AD) using Intravenous Immune Globulin (IGIV), also known as gammaglobulin.   view more (2009-09-24)

Scientists begin to untangle root cause of Alzheimer's disease
"N60" might not be the first thing that comes to mind when people think of Alzheimer's disease, but thanks to researchers from the United States, South Korea and France, this might change.   view more (2009-09-04)

Hybrid molecules show promise for exploring, treating Alzheimer's
One of the many mysteries of Alzheimer's disease is how protein-like snippets called amyloid-beta peptides, which clump together to form plaques in the brain, may cause cell death, leading to the disease's devastating symptoms of memory loss and other mental difficulties.   view more (2009-11-05)

Alzheimer's disease prevention may be easier than cure
Current hypotheses suggest that it is the accumulation over time of amyloid beta peptide 1-42 (Abeta42) that triggers changes in the brain that lead to cognitive dysfunction in Alzheimer's disease.   view more (2005-12-09)

Study validates Pittsburgh Compound-B in identifying Alzheimer's disease brain toxins
A groundbreaking study conducted by University of Pittsburgh Alzheimer's disease researchers reported in the journal Brain (currently online) confirms that Pittsburgh Compound-B (PiB) binds to the telltale beta-amyloid deposits found in the brains of patients with Alzheimer's disease.   view more (2008-03-27)

Alzheimer's vaccine clears plaque but has little effect on learning and memory impairment
A promising vaccine being tested for Alzheimer's disease does what it is designed to do - clear beta-amyloid plaques from the brain - but it does not seem to help restore lost learning and memory abilities, according to a University of California, Irvine study.   view more (2008-04-07)

Study outlines how stroke, head injury can increase risk of Alzheimer's disease
Researchers from the MassGeneral Institute for Neurodegenerative Disorders (MGH-MIND) have discovered how the death of brain cells caused by a stroke or head injury may cause generation of amyloid-beta protein - the key component of senile plaques seen in the brains of patients with Alzheimer's disease.   view more (2007-06-07)

Vitamin D, curcumin may help clear amyloid plaques found in Alzheimer's disease
UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease.    view more (2009-07-16)

Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers
The destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC).   view more (2009-07-13)

Blocking immune cell action increases Alzheimer's-associated protein deposits
The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder.   view more (2007-03-28)

Rapid changes in key Alzheimer's protein described in humans
For the first time, researchers have described hour-by-hour changes in the amount of amyloid beta, a protein that is believed to play a key role in Alzheimer's disease, in the human brain.   view more (2008-08-29)

Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned
Scientists have shown that recently developed mouse breeds that mimic the symptoms of Alzheimer's disease (AD) may not be as effective as previously assumed.   view more (2007-08-17)

UCLA scientists identify how immune cells may help predict Alzheimer's risk
What if you could test your risk for Alzheimer's disease much like your cholesterol levels - through a simple blood test?   view more (2009-07-14)

The immune system and Alzheimer's disease
Utrecht researchers, funded by NWO, have determined the role played by brain cells from the immune system that are located close to dying memory cells. The research will help determine the causes of Alzheimer's disease. In patients with Alzheimer's disease, the brain cells die off. The death of these neurones takes place primarily in the vicinity... view more... (2001-11-27)

Alzheimer's-associated enzyme can disrupt neural activity in the brain
An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures.   view more (2007-06-18)

NIST membrane model may unlock secrets of early-stage Alzheimer's
Researchers at the National Institute of Standards and Technology (NIST) and three collaborating institutions are using a new laboratory model of the membrane surrounding neurons in the brain to study how a protein long suspected of a role in early-stage Alzheimer's disease actually impairs a neuron's structure and function.   view more (2008-07-24)

New strategy for protecting brain against Alzheimer's disease: Enhancing the innate immune system
The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer's disease have an immune defect making it difficult to clean away these wastes.   view more (2005-06-10)

Seeing Alzheimer's amyloids
In an important step toward demystifying the role protein clumps play in the development of neurodegenerative disease, researchers have created a stunning three-dimensional picture of an Alzheimer's peptide aggregate using electron microscopy.   view more (2008-05-13)

Scientists develop a new way to target Alzheimer's disease
The pathological embrace between two proteins plays a key role in the development of Alzheimer's disease by triggering the formation of neuron-killing plaques of amyloid beta protein. Now a group of scientists at NYU School of Medicine have devised a way to reduce amyloid beta deposition by interfering with the deadly embrace of these proteins.   view more (2006-12-05)
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