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A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported.   view more (2005-11-01)

Study reveals a reprogrammed role for the androgen receptor
The androgen receptor - a protein ignition switch for prostate cancer cell growth and division - is a master of adaptability.   view more (2009-07-28)

Active compounds found in Ganoderma lucidum fungus with potential to treat prostate cancer
A new development in the fight against cancer: Recent research at the University of Haifa found that molecules found in common fungus Ganoderma lucidum aid in suppressing some of the mechanisms involved in the progression of prostate cancer.   view more (2007-12-12)

Protein that suppresses androgen receptors could improve prostate cancer diagnosis, treatment
A protein that helps regulate expression of androgen receptors could prove a new focal point for staging and treating testosterone-fueled prostate cancer, Medical College of Georgia researchers say.   view more (2009-05-21)

Seeking better cancer treatments
EUREKA project E! 1948 SASTEREC and its follow-up E! 2705 SAMARDES carried out essential research with the human androgen receptor to understand the mechanism of the mode of action of androgens. The human androgen receptor (hAR) binds the male sex steroids and regulates genes for male differentiation and development.   view more (2004-11-16)

Why prostate cancer patients fail hormone deprivation therapy
The hormone deprivation therapy that prostate cancer patients often take gives them only a temporary fix, with tumors usually regaining their hold within a couple of years.   view more (2009-01-05)

Urologist plays key role in determining use of hormone therapy in prostate cancer
The urologist a patient sees may be a more important factor than the tumor characteristics or the patient's other characteristics in determining the use of hormonal therapy for prostate cancer.   view more (2006-06-21)

Novel enzyme offers new look at male hormone regulation
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent.   view more (2006-05-08)

Prostate cancer therapy linked to increased risk of heart disease death
The use of androgen deprivation therapy to treat localized prostate cancer is associated with an increased risk of death from heart disease.   view more (2007-10-10)

Prostate Cancer Survival Benefit From A Combination Of Androgen Suppression And External Irradiation
Disease-free survival from advanced prostate cancer could be almost doubled if hormone-suppression therapy is used during and after radiotherapy for a duration of 3 years, suggest authors of an international study in this week's issue of THE LANCET. Long-term survival after radiotherapy for people with advanced prostate cancer is poor. Michel... view more... (2002-07-05)

Many men with low testosterone levels do not receive treatment
The majority of men with androgen deficiency may not be receiving treatment despite having sufficient access to care, according to a report in the May 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2008-05-27)

Scientists find one reason why bladder cancer hits more men
Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease. The finding could open the door to new types of treatment with the disease.   view more (2007-04-23)

Why a common treatment for prostate cancer ultimately fails
Some of the drugs given to many men during their fight against prostate cancer can actually spur some cancer cells to grow, researchers have found. The findings were published online this week in a pair of papers in the Proceedings of the National Academy of Sciences.   view more (2008-08-22)

Study implicates protein as a trigger of advanced prostate cancer recurrence
Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.   view more (2007-05-09)

BUSM researchers propose a relationship between androgen deficiency and cardiovascular disease
Researchers from Boston University School of Medicine (BUSM) in collaboration with researchers from Lahey Clinic Northshore, Peabody, Mass., believe that androgen deficiency might be the underlying cause for a variety of common clinical conditions, including diabetes, erectile dysfunction, metabolic syndrome and cardiovascular disease (CVD).   view more (2009-09-28)

Tendency to hair loss inherited from the mother
The male sex hormones really do seem to play a decisive role in causing hair loss in men. This has been confirmed by scientists from the universities of Bonn and Düsseldorf. Their studies show that specific changes in the genetic 'construction manual' of the androgen receptor may result in premature balding. Androgens are hormones which play... view more... (2005-05-20)

New medications show promise in treating drug-resistant prostate cancer
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.   view more (2009-04-08)

How DDT metabolite disrupts breast cancer cells
Research has shown that the main metabolite of the insecticide DDT could be associated with aggressive breast cancer tumours, but there has been no explanation for this observation to date. Now a report published in the open access journal Breast Cancer Research shows how DDT could act to disrupt hormone-sensitive breast cancer cells.   view more (2008-02-14)

New drug shows promise in treating drug-resistant prostate cancer
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.   view more (2009-04-10)

Prostate cancer patients undergoing hormone therapy may experience cognitive effects
A recent review of the literature has found that hormone deprivation therapy, a commonly used treatment for prostate cancer, may have subtle adverse effects on cognition in patients-- such as in the ability to recall and concentrate.   view more (2008-07-28)
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