Androgen Receptor Current Events | Androgen Receptor News | 11
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Gene determines whether male body odor smells pleasant
To many, urine smells like urine and vanilla smells like vanilla. But androstenone, a derivative of testosterone that is a potent ingredient in male body odor, can smell like either - depending on your genes. view more (2007-09-17)
Prenatal cocaine's lasting cellular effects
Although the "crack baby" hysteria of the 1980s was greatly exaggerated, cocaine use during pregnancy can cause subtle but disabling cognitive impairments — attention deficits, learning disabilities and emotional problems. view more (2007-01-15)
MIT IDs link between brain tumor proteins
MIT researchers have identified a critical link between two proteins found in brain tumors, a discovery that could eventually help treat a form of brain cancer that kills 99 percent of patients. view more (2007-07-20)
Ob1, the first commmon obesity gene was located on chromosome 10
Each family has at least one member whose body mass index (BMI, the ratio of the weight in kg to the surface of the body in m2; normal BMI is below 25) is higher than 40 and at least one other member whose BMI is over 27. 380 genetic markers, covering 23 pairs of chromosomes, were studied in order to find genetic similarities between the obese... view more... (1998-11-16)
Life and death in the hippocampus: what young neurons need to survive
Whether newborn nerve cells in adult brains live or die depends on whether they can muscle their way into networks occupied by mature neurons. view more (2006-08-14)
Science researchers genetically transform immune cells into tumor fighters
A team of researchers has genetically engineered normal immune cells to become specialized tumor fighters, demonstrating for the first time that these engineered cells can persist in the body and shrink large tumors in humans. view more (2006-09-01)
Potential new approach to treat cognitive impairments in schizophrenia
A new study reports important evidence for a potential new treatment approach for those diagnosed with schizophrenia. Schizophrenia is considered one of the most devastating of the major psychiatric disorders, which has three distinct facets, often referred to as "positive" (hallucinations, delusions), "negative" (blunted... view more... (2007-09-25)
Iressa shows promise for treatment of metastatic breast cancer when combined with hormonal therapy
Gefitinib, the once-promising drug formerly approved as a second line treatment for lung cancer, also known as Iressa, enhanced the effectiveness of hormonal therapy for the treatment of specific types of metastatic breast cancer. view more (2008-05-19)
International conference on endothelin
One of the most intriguing developments in recent medical science is the discovery of the human chemical endothelin (ET). view more (2009-09-10)
Unexpected role: EGFR protects cancer cells from starving
A growth factor receptor found abundantly on the surface of cancer cells and long known to fuel cancer growth also protects tumor cells from starvation by a newly identified mechanism. view more (2008-05-06)
Small molecule inhibitor shows promise in trastuzumab-resistant metastatic breast cancer
Fox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast cancer who have progressed on previous trastuzumab based therapies. view more (2009-05-29)
Scientists discover major genetic cause of colorectal cancer
About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases. view more (2008-08-15)
Leptin has powerful effect on reward center in the brain
Leptin, a hormone critical for normal food intake and metabolism, exerts a strong effect on appetite by acting in the mid-brain region as well as in the hypothalamus. view more (2006-09-29)
Variants of 'umami' taste receptor contribute to our individualized flavor worlds
Using a combination of sensory, genetic, and in vitro approaches, researchers from the Monell Center confirm that the T1R1-T1R3 taste receptor plays a role in human umami (amino acid) taste. view more (2009-07-09)
Novel compounds show promise as safer, more potent insecticides
Research teams at Nihon Nohyaku Co., Ltd., Bayer CropScience and DuPont have developed two new classes of broad-spectrum insecticides that show promise as a safer and more effective way to fight pest insects that damage food crops. view more (2005-08-29)
Researchers Discover Method in Mice to Restore Tamoxifen Sensitivity in Resistant Breast Cancer
The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, and their partners. view more (2006-12-21)
Gene expression test reveals ER and HER-2 status of breast tumors
Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. view more (2007-02-15)
Study helps explain why botulinum toxin is so deadly
A pilot without a map can locate an airport by first finding a nearby landmark, like a big river, and then searching for the airport. view more (2006-12-14)
Cell surface receptors are all 'talk' in T cell stimulation
Understanding the mechanisms that drive healthy immune responses is important when it comes to combating autoimmune diseases, which occur when cells that should attack invading organisms turn on the body instead. view more (2008-06-13)
Immune system discovery could aid fight against TB
A key aspect of how the body kicks the immune system into action against tuberculosis is revealed in research published today. view more (2006-10-23)
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