Androgen Receptor Current Events | Androgen Receptor News | 5
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Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
The epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) are involved in the carcinogenesis of many malignancies. view more (2009-10-16)
Colon cancer shuts down receptor that could shut it down
Though a high-fiber diet has long been considered good for you and beneficial in staving off colon cancer, Medical College of Georgia researchers have discovered a reason why: roughage activates a receptor with cancer-killing potential. view more (2009-04-14)
Many receptor models used in drug design may not be useful after all
It may very well be that models used for the design of new drugs have to be regarded as impractical. This is the sobering though important conclusion of the work of two Leiden University scientists published in Science this week. view more (2008-10-03)
Polycystic ovary syndrome more prevalent in overweight women
Overweight and obese Spanish women appear five times as likely as lean women to have polycystic ovary syndrome, a condition that decreases fertility and contributes to other illnesses. view more (2006-10-24)
Meth Promotes Spread of Virus in HIV-Infected Users
Researchers at the University at Buffalo have presented the first evidence that the addictive drug methamphetamine, or meth, also commonly known as "speed" or "crystal," increases production of a docking protein that promotes the spread of the HIV-1 virus in infected users. view more (2006-08-07)
Toward an explanation for Crohn's disease?
Twenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease. view more (2009-07-10)
Researchers may have unlocked the mechanisms that silence the estrogen receptor gene alpha during breast cancer
The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked. view more (2007-08-20)
Newly discovered epidermal growth factor receptor active in human pancreatic cancers
Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approximately a third of the 250 human pancreatic cancers... view more... (2009-04-20)
UAB research could boost coastal economics with crustacean molting on demand
University of Alabama at Birmingham (UAB) researchers are close to unraveling intricate cellular pathways that control molting in blue crabs. The discoveries could revolutionize the soft-shell crab industry, generating new jobs and additional profits for the U.S. fishing industry along the coastal Southeast. view more (2009-10-28)
Vitamin D compounds show promise for prevention of prostate cancer
The active metabolite of vitamin D, calcitriol, and other vitamin D analogs are promising chemopreventive agents that may prevent prostate cancer. view more (2005-11-02)
Nicotine may have more profound impact than previously thought
Nicotine isn't just addictive. It may also interfere with dozens of cellular interactions in the body, new Brown University research suggests. view more (2009-04-06)
Biosensor sniffs out explosives
Temple University School of Medicine researchers have developed a new biosensor that sniffs out explosives and could one day be used to detect landmines and deadly agents, such as sarin gas, according to a paper in the June issue of Nature Chemical Biology. view more (2007-05-09)
Prostate cancer research may be faster with PSA endpoints
A new study from Columbia University Medical Center researchers at NewYork-Presbyterian Hospital/Columbia, who are members of the Southwest Oncology Group (SWOG), suggests that certain changes in prostate-specific antigen (PSA) levels may serve as surrogate endpoints for prostate cancer survival. view more (2006-04-19)
Cell-death receptor links cancer susceptibility and inflammation
For over 10 years, Wafik S. El-Deiry, MD, PhD, Professor of Medicine, Genetics, and Pharmacology at the University of Pennsylvania School of Medicine, has been pursuing a cancer-targeting molecule called TRAIL and its molecular partners. view more (2007-12-28)
New Genetic Marker for Osteoarthritis - Study Links Estrogen Receptor to Osteoarthritis in Both Men and Women
Among patients with osteoarthritis (OA), a degenerative joint disease, postmenopausal women are the most prevalent. This fact has led to many hypotheses about the role of sex hormones in the cause and effects of OA. Medical researchers at Erasmus MC in the Netherlands recently uncovered a compelling connection between a variation in gene for the... view more... (2003-06-26)
IL-21 receptor plays an essential role in the Th2 immune response
During the immune response cells known as Th2 cells express a variety of cytokines (e.g. interleukin-4, -5, and -13), many of which stimulate B cells to proliferate and produce antibodies. view more (2006-06-16)
UAB Researchers Discover Antibody Receptor Identity, Propose Renaming Immune-System Gene
Researchers at the University of Alabama at Birmingham (UAB) have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders. view more (2009-11-20)
Study connects obesity with nervous system
A discovery by Queen's biologists and their students sheds new light on the genetic roots of obesity - a condition that is increasing dramatically in North America and has been linked to heart disease, diabetes and some forms of cancer. view more (2008-01-24)
Researchers may have found why women have an edge on salt-sensitive hypertension
Researchers may have found why women have an edge in keeping a healthier balance between the amount of salt they eat and excrete - at least before reaching menopause. view more (2009-01-29)
Why don't brain tumors respond to medication?
Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance. view more (2009-09-01)
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