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Androgen Receptor Current Events | Androgen Receptor News | 6

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Variation in bitter-taste receptor gene increases risk for alcoholism
A team of researchers, led by investigators at Washington University School of Medicine in St. Louis, has found that a gene variant for a bitter-taste receptor on the tongue is associated with an increased risk for alcohol dependence.   view more (2006-01-10)

Biologists spy close-up view of poliovirus linked to host cell receptor
Researchers from Purdue and Stony Brook universities have determined the precise atomic-scale structure of the poliovirus attached to key receptor molecules in human host cells and also have taken a vital snapshot of processes leading to infection.    view more (2008-12-09)

A new system for collaboration in cell communication
Investigators from the Institute of Research in Biomedicine (IRB Barcelona) have identified a new signalling mechanism among cells in the fruit fly, Drosophila melanogaster.   view more (2007-06-27)

Glutamate: Too much of a good thing in schizophrenia?
Is schizophrenia a disorder of glutamate hyperactivity or hypoactivity? While the predominant hypothesis for many years was that schizophrenia was a glutamate deficit disorder, there is growing evidence of glutamate hyperactivity as well.   view more (2008-10-28)

UNC scientists discover 'gatekeeper' protein in blood clotting
New research from the University of North Carolina at Chapel Hill School of Medicine has identified a protein that may control blood clotting by keeping blood platelets from sticking together.   view more (2006-01-30)

Wasabi's kick linked to single pain receptor
A single pain receptor is responsible for the kick delivered by garlic and mustard oil, which is the active ingredient in mustard and in the pungent green sushi condiment known as wasabi, according to a Yale School of Medicine study published this week in Cell.   view more (2006-03-27)

Discovery of 'sugar sensor' in intestine could benefit diabetes
Diabetes patients could benefit from new research at the University of Liverpool that has identified a molecule in the intestine that can 'taste' the sugar content of the diet.   view more (2007-08-22)

Olfactory nerve cells expressing same receptor display a varied set of reactions
n a mouse model, University of Pennsylvania School of Medicine researchers discovered that olfactory sensory neurons expressing the same receptor responded to a specific odor with an array of speeds and sensitivities.   view more (2006-02-03)

Tarantula venom and chili peppers target same pain sensor
Venom from a West Indian tarantula has been shown to cause pain by exciting the same nerve cells in mice that sense high temperatures and the hot, spicy ingredient in chili peppers.   view more (2006-11-09)

Potential new targets for antidepressant medications
The news about antidepressant medications over the past several years has been mixed. The bad news from large multicenter studies such as STAR*D is that current antidepressant medications are effective, but not as effective as one might hope. Thus, there is a significant need for new treatment mechanisms for depression.   view more (2008-08-27)

Dual role in breast tissue for a protein involved in leukemia
A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC).   view more (2009-06-15)

Marijuana-like compounds suppress the immune response
A group of Japanese scientists has discovered that cannabinoids can cause some white blood cells to lose their ability to migrate to the sites of infection and inflammation.   view more (2006-04-27)

Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
Genetically modifying a receptor found on the neurons that produce the neurotransmitter dopamine has given California Institute of Technology (Caltech) researchers a unique glimpse into the workings of the brain's dopamine system--as well as a new target for treating diseases that result from either too much or too little of this critical... view more... (2008-10-15)

Food restriction increases dopamine receptor levels in obese rats
A brain-imaging study of genetically obese rats conducted at the U.S. Department of Energy's Brookhaven National Laboratory provides more evidence that dopamine - a brain chemical associated with reward, pleasure, movement, and motivation - plays a role in obesity.   view more (2007-10-25)

General anesthetics lead to learning disabilities in animal models
Studies by researchers at Wake Forest University School of Medicine have shown that blocking the NMDA receptor in immature rats leads to profound, rapid brain injury and disruption of auditory function as the animals mature.   view more (2009-10-23)

Ashwell receptor reduces mortality during sepsis
In research that solves the longest-standing mystery in glycobiology - a field that studies complex sugar chains called glycans - researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is critical in helping the body fight off the abnormal... view more... (2008-05-19)

CSHL team solves structure of NMDA receptor unit that could be drug target for neurological diseases
A team of scientists at Cold Spring Harbor Laboratory (CSHL) reports on Thursday their success in solving the molecular structure of a key portion of a cellular receptor implicated in Alzheimer's, Parkinson's, and other serious illnesses.   view more (2009-11-12)

Study advances evidence for receptor's role in alcohol pleasure and problems
A genetic variant of a receptor in the brain's reward circuitry heightens the stimulating effects of early exposures to alcohol and increases alcohol consumption, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).   view more (2007-03-07)

Estrogen withdrawal results in bone loss, research shows that the Estrogen Receptor has a fundamental role
Professor Lance Lanyon, Principal of The Royal Veterinary College, Karla Lee, Helen Jessop, Rosemary Suswillo, Gul Zaman from the Department of Basic Sciences at The Royal Veterinary College have shown in their research that the Estrogen Receptor has a fundamental role in bone cells by adjusting the bone architecture to match the loads individuals... view more... (2003-07-25)

A double-barreled immune cell approach for neuroblastoma
Adding an artificial tumor-specific receptor to immune system cells called T-lymphocytes that target a particular virus extended and improved the cells' ability to fight a form of childhood cancer called neuroblastoma, said researchers form Baylor College of Medicine and Texas Children's Hospital in a report that appears online today in the... view more... (2008-11-03)
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