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Researchers identify new drug targets for cancer
Solving a 100-year-old genetic puzzle, researchers at the University of California, San Diego (UCSD) School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor.   view more (2007-01-02)

Chromosomal abnormalities in sperm higher after vasectomy reversal
Men who have had a vasectomy reversed have a very much greater rate of chromosomal abnormalities in their sperm than do normal fertile men.   view more (2006-06-21)

Levels of folate in men's diets is linked to chromosomal abnormalities in their sperm
Researchers have found an association between a vitamin found in leafy green vegetables, fruit and pulses and levels of chromosomal abnormalities in men's sperm. Men who consumed high levels of folate (a water-soluble B vitamin that occurs naturally in food) and folic acid (the synthetic form of... view more (2008-03-20)

New study finds amniocentesis safer for pregnant women
Amniocentesis is the most commonly prescribed invasive test performed during pregnancies in the United States.   view more (2006-11-01)

MIT sheds light on how tumor cells form
MIT cancer researchers have discovered a process that may explain how some tumor cells form, a discovery that could one day lead to new therapies that prevent defective cells from growing and spreading.   view more (2006-06-22)

Support for chromosomal theory of cancer found in cancers' development of drug resistance
Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance.   view more (2007-06-28)

Common viruses may cause cancer
In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences... view more (2005-11-09)

'Signature' of chromosome instability predicts cancer outcomes
Microscopic examination of tumor specimens cannot always predict a cancer's aggressiveness, leading to increased interest in molecular approaches to diagnosis.   view more (2006-08-21)

Study links dietary folate intake to genetic abnormalities in sperm
Healthy men who report lower levels of the nutrient folate in their diets have higher rates of chromosomal abnormalities in their sperm, according to a new study by researchers at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory.   view more (2008-03-20)

Double identities lie behind chromosome disorders
Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in the scientific journal Nature Genetics shows how chromosome disorders can arise when sex cells are formed.   view more (2007-07-09)

Geneticists aim to develop test to identify learning disability
Clinical geneticist and principal investigator Dr David FitzPatrick explains: "In approximately 10% of CGMH cases, the condition will be caused by a chromosomal abnormality such as a chromosome 21 problem as in Down's Syndrome. Recent studies have suggested that a further 6% of cases may be caused... view more (2000-01-20)

'QUADRUPLE TEST' OFFERS BEST PREDICTION FOR DOWN'S SYNDROME (pp 794, 835)
Authors of a research letter in this week's issue of THE LANCET highlight how screening for Down's syndrome based on maternal age and four markers in maternal blood should be used worldwide-the quadruple test is far more effective than screening based on maternal age alone. Screening for Down's... view more (2003-03-05)

New method of testing eggs for abnormalities could solve problems of embryo freezing
Italian researchers have shown for the first time that it is possible to test a woman's egg, before fertilisation, for chromosomal abnormalities that might make an embryo less likely to implant successfully or more likely to miscarry at a later stage.   view more (2006-06-19)

Preimplantation Genetic Diagnosis (PGD) should be allowed in Germany: study reveals demand for a change in the law
Current legislation on preimplantation genetic diagnosis (PGD) in Germany is out of step with the attitudes of Germans and should be changed, researchers told a news briefing at the 20th annual meeting of the European Society of Human Reproduction and Embryology on Monday 28 June). At present PGD... view more (2004-06-28)

ICSI: Is it really safe?
The absolute risk of having a baby with a serious congenital malformation or chromosomal abnormality as a result of using ICSI* is small, Dr Ulla-Britt Wennerholm told a news briefing today (Monday 1 July) at the annual conference of the European Society of Human Reproduction and Embryology in... view more (2002-06-29)

Chromosomal chaos in early embryonic development is linked to abnormalities in cytokinesis and spindle formation
Berlin, Germany: Abnormalities in the spindles (the bi-polar thread like structures that link and pull the chromosomes during cell division) of human embryos before implantation may be the primary reason for many of the chromosome defects observed in early human development, a scientist said on... view more (2004-06-29)

'Network' approach identifies potential breast cancer susceptibility gene
Like a crossword-puzzle solver who uses the letters in some answers to figure out others, researchers at Dana-Farber Cancer Institute and an international group of collaborators have used data on genes involved in inherited forms of breast cancer to identify a gene linked to non-hereditary cases of... view more (2007-10-10)
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