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Angiogenesis Current Events | Angiogenesis News | 3

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Study shows blood markers can help choose best dose for antiangiogenic drugs
Scientists at Sunnybrook have new information that may help to improve the use of anti-cancer drugs designed to block the growth of new blood vessels in tumors, a process called angiogenesis that is critical to tumor growth.   view more (2007-10-26)

Why do people with Down syndrome have less cancer?
Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population.    view more (2009-05-21)

Anti-angiogenesis treatment improves hearing in some NF2 patients
Treatment with the angiogenesis inhibitor bevacizumab improved hearing and alleviated other symptoms in patients with neurofibromatosis type 2 (NF2).   view more (2009-07-09)

Angiogenesis linked to poor survival in patients with rare type of ovarian cancer
Researchers from The University of Texas M. D. Anderson Cancer Center have found that increased angiogenesis, or blood vessel formation, and vascular endothelial growth factor expression are associated with poor survival in women with sex cord-stromal ovarian tumors.   view more (2009-02-06)

Ingredient Found In Green Tea Significantly Inhibits Breast Cancer Growth In Female Mice
Green tea is high in the antioxidant EGCG (epigallocatechin-3- gallate) which helps prevent the body's cells from becoming damaged and prematurely aged.   view more (2008-04-08)

A black and white look at breast cancer mortality
African and African American women are more likely to die of breast cancer than their white counterparts because they tend to get the disease before the menopause.   view more (2007-02-21)

USC researchers show that molecular markers predict tumor recurrence
Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.   view more (2007-06-06)

Cancer drugs my build and not tear down blood vessels
Scientists have thought that one way to foil a tumor from generating blood vessels to feed its growth - a process called angiogenesis - was by creating drugs aimed at stopping a key vessel growth-promoting protein. But now the opposite seems to be true.   view more (2008-11-10)

Turmeric extract suppresses fat tissue growth in rodent models
Curcumin, the major polyphenol found in turmeric, appears to reduce weight gain in mice and suppress the growth of fat tissue in mice and cell models.   view more (2009-05-19)

Study sheds light on angiogenesis inhibitors, points to limitations, solutions
A new generation of cancer drugs designed to starve tumors of their blood supply - called "angiogenesis inhibitors"-succeeds at first, but then promotes more invasive cancer growth-sometimes with a higher incidence of metastases, according to a new study in animals.   view more (2009-03-03)

New angiogenesis inhibitor has promise for treating deadly brain tumor
Researchers from the Massachusetts General Hospital (MGH) Cancer Center have found that AZD2171 (RECENTIN(tm)), a new angiogenesis inhibitor, can significantly reduce the size of the deadly brain tumors called glioblastomas and has the potential of improving the effectiveness of other therapeutic techniques.   view more (2007-01-17)

Gene signal GS-101 data shows safe and effective inhibition of ophthalmic blood vessel growth
Gene Signal, a company focused on developing innovative drugs to manage angiogenesis based conditions, today announced the publication of interim results from a phase II study suggesting that the antisense oligonucleotide GS-101 (eye drops) is safe and effective at inhibiting and regressing corneal neovascularisation (abnormal new blood vessel... view more... (2009-09-01)

New oral angiogenesis inhibitor offers potential nontoxic therapy for a wide range of cancers
The first oral, broad-spectrum angiogenesis inhibitor, specially formulated through nanotechnology, shows promising anticancer results in mice, report researchers from Children's Hospital Boston.   view more (2008-07-02)

Rescuing injured hearts by enhancing regeneration
Using a two-drug approach, researchers at Children's Hospital Boston have demonstrated that it may be possible to rescue heart function after a heart attack and protect the heart from scarring.   view more (2006-10-10)

Novel findings about neovessel formation
The main role in new findings about neovessel formation is played by a protein called tissue factor. This factor turns out to have both a stimulatory function and an inhibitory function in the generation of blood vessels. Normally these two functions neutralize each other, but in diseases like retinopathy - where unwanted blood vessels grow into... view more... (2004-05-10)

Humble yeast sheds light on promising anti-cancer drug
The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.   view more (2005-10-19)

Nutrients in certain vegetables may provide cancer-fighting benefit
Chemicals in cruciferous vegetables, such as broccoli, watercress, cabbage and cauliflower, appear to not only stop human prostate cancer cells from growing in mice but also may cut off the formation of blood vessels that "feed" tumors.   view more (2007-04-18)

Scripps research combination therapy obliterates new vessel growth in tumors and retinopathy
While new blood vessel growth from preexisting capillaries ("angiogenesis") is fundamental to survival, the abnormal formation of new blood vessels ("neovascularization") contributes to the pathogenesis of tumor growth and metastasis as well as the vast majority of diseases that lead to catastrophic loss of vision.   view more (2007-01-11)

New technique appears to stop abnormal blood vessel growth
A manmade protein with a tail of amino acids delivered to target cells can dramatically reduce blood vessel growth that obstructs vision or feeds a tumor, researchers have found.   view more (2005-06-01)

Northwestern researchers launch Avastin trial for pancreatic tumors
Avastin is designed to inhibit Vascular Endothelial Growth Factor (VEGF), a protein that plays an important role in tumor angiogenesis or blood vessel formation, and maintenance of existing tumor vessels.   view more (2006-02-22)
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