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Diesel exhaust is linked to cancer development via new blood vessel growth
Scientists here have demonstrated that the link between diesel fume exposure and cancer lies in how diesel exhaust induces the growth of new blood vessels that supply solid tumors. The researchers found that in both healthy and diseased animals, more new blood vessels sprouted in mice exposed to diesel exhaust than did in mice exposed to clean,... view more... (2009-09-03)

Gladstone scientists identify single microRNA that controls blood vessel development
Scientists from the Gladstone Institute of Cardiovascular Disease (GICD) and UCSF have identified a key regulatory factor that controls development of the human vascular system, the extensive network of arteries, veins, and capillaries that allow blood to reach all tissues and organs.   view more (2008-08-12)

Study reveals a key to blood vessel growth and possible drug target
Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and... view more... (2007-10-15)

Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma.   view more (2006-06-21)

Rapid, Functional, Genome-wide Drug Discovery Enabled
Munich, Germany, November 18th, 2003. Xantos Biomedicine AG, a leading functional biology and drug discovery company, announced that it has expanded its collection of full-length human cDNA clones in mammalian expression vectors to 35,000, representing one of the world's largest collections. The Xantos human cDNA collection covers individual cDNA... view more... (2003-11-18)

Lung damage in babies with congenital heart disease under study
Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study.   view more (2008-03-11)

Novel Discoveries Leading To Targeted Treatment Of Lymphatic Diseases
A gene responsible for lymphatic vessel formation Novel discoveries at the University of Helsinki, Finland, about the development of the lymphatic network may help researchers to better understand the mechanisms of cancer and its metastasis, and also diseases such as lymphedema, wound healing and inflammatory and autoimmune disorders. Lymphatic... view more... (2003-11-20)

Systemic treatment before surgery for kidney cancer prolongs patients' survival
Preliminary results from a phase II clinical trial have provided the first evidence that treating people with kidney cancer with bevacizumab and erlotinib before surgery is safe, effective and may prolong patients' survival.   view more (2006-11-09)

New study finds key role for VEGF in onset of sepsis
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that the vascular endothelial growth factor (VEGF) protein is a key biomarker for sepsis, a severe inflammatory response that develops following a bacterial infection.   view more (2006-05-22)

New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene.   view more (2008-05-09)

Fibroblasts invade at a snail's pace
A transcription factor known to drive the formation of fibroblasts during development also promotes their ability to invade and remodel surrounding tissues, report Rowe et al. in the February 9, 2009 issue of the Journal of Cell Biology.   view more (2009-02-02)

Prostate cancer spurs new nerves
Prostate cancer - and perhaps other cancers - promotes the growth of new nerves and the branching axons that carry their messages, a finding associated with more aggressive tumors, said researchers from Baylor College of Medicine in the first report of the phenomenon that appears today in the journal Clinical Cancer Research.   view more (2008-12-01)

Study first: Over-expression of Cox-2 can predict prostate cancer outcome
Researchers say an over-expression of COX-2 in men with prostate cancer is associated with an increase in PSA after radiation treatment and the spread of the cancer outside of the prostate.   view more (2006-11-09)

Researchers announce new predictor for lung cancer treatment and survival
Research from the Ireland Cancer Center of University Hospitals of Cleveland has found a promising, novel biomarker that may be used to predict the survival of patients with advanced lung cancer and their response to treatment.   view more (2006-06-06)

Study broadens understanding of enzymes linked to tumor promoting molecule
Virginia Commonwealth University Massey Cancer Center researchers have found that two enzymes that catalyze the same reaction and produce the same product have opposite effects on cell growth and death.   view more (2005-11-07)

Enzyme eliminated by cancer cells holds promise for cancer treatment
An enzyme that cancer cells eliminate, apparently so they can keep proliferating, may hold clues to more targeted, effective cancer treatment, scientists say.   view more (2007-07-19)

UCSF scientists illuminate how microRNAs drive tumor progression
UCSF researchers have identified collections of tiny molecules known as microRNAs that affect distinct processes critical for the progression of cancer.   view more (2009-09-17)

Scientists discover why cornea is transparent and free of blood vessels, allowing vision
Scientists at the Harvard Department of Ophthalmology's Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary (MEEI) are the first to learn why the cornea, the clear window of the eye, is free of blood vessels-a unique phenomenon that makes vision possible.   view more (2006-07-18)

New study shows way to avoid overtreatment in breast cancer
The numbers of women who receive adjuvant chemotherapy for breast cancer could be reduced by 30 to 40% if the results of a new molecular study are put into practice. Dr Laura van 't Veer from the Netherlands Cancer Institute told the news briefing that micro array technology* can help predict which breast cancers will metastasise (spread) and... view more... (2002-03-20)

First report that apoptotic and anti-angiogenic therapies work better together than alone
American researchers have found that giving a combination of imantanib (Glivec) and a drug that induces cell death (apoptosis) was better at inhibiting the growth of Ewing's sarcoma in mice than either therapy on its own.   view more (2006-11-13)
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