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Angiogenesis Current Events | Angiogenesis News | 6

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Pathway links inflammation, angiogenesis and breast cancer
A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells.   view more (2007-08-10)

Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer.   view more (2007-12-26)

Compound reveals new link between signaling protein and cell migration
University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells.   view more (2005-09-26)

Angiotensin inhibitors and receptor blockers linked to lower risk of nonmelanoma skin cancer
The use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) was associated with a reduced risk of basal cell or squamous cell skin cancers in U.S. veterans, researchers report in the August 26 online issue of the Journal of the National Cancer Institute.   view more (2008-08-27)

Scientists Uncover Mechanism of Response to Targeted Therapy in Kidney Cancer
UCLA researchers knew-based on two clinical trials-that a subset of kidney cancer patients responded well to an experimental targeted therapy, but they didn't know why.   view more (2006-01-13)

Avastin effective at delaying brain tumor progression in recurrent disease
The use of Avastin alone to treat a subgroup of recurrent Grade 3 brain tumors showed it was safe and effective at delaying tumor progression, according to a retrospective study of 22 patients conducted by a researcher at the Seattle Cancer Care Alliance.   view more (2009-04-07)

Drug fends off kidney cancer progression
New data from an international, multicenter Phase III clinical trial has found that the experimental targeted therapy everolimus (RAD001) significantly delays cancer progression in patients with metastatic kidney cancer whose disease had worsened on other treatments.   view more (2008-05-19)

Stem cell infusion and hyperbaric oxygen treatment improve islet function in diabetes
A study to determine if patients with type 2 diabetes can benefit from a combination of autologous (patient self-donated) stem cell infusions (ASC) and hyperbaric (above the normal air pressure of ) oxygen treatment (HBO) before and after ASC has found "significant benefits" in terms of "improvements in glycemic control" along... view more... (2009-03-13)

FSU researcher's 'mutant' proteins could lead to new treatment for heart disease
Heart damage due to blocked arteries remains the leading cause of disease and death in the Western world, but a Florida State University College of Medicine researcher is helping to open new pathways toward treating the problem.   view more (2008-03-25)

Is short-term Celecoxib intervention a effective method for preventing gastric carcinogenesis?
Since the isolation and culture of Helicobacter pylori (H. pylori) in 1983, this bacterium has become accepted as an important human pathogen for the development of gastritis, peptic ulcer, and gastric cancer.   view more (2009-10-29)

Asian Spice Could Reduce Breast Cancer Risk in Postmenopausal Women Exposed to Hormone Replacement Therapy, MU Study Finds
Previous studies have found that postmenopausal women who have taken a combined estrogen and progestin hormone replacement therapy have increased their risk of developing progestin-accelerated breast tumors.   view more (2009-07-14)

CSHL scientists successfully target tumor microenvironment to stop cancer growth
Cold Spring Harbor Laboratory (CSHL) researchers led by Daniel Nolan and Assistant Professor Vivek Mittal have found that bone marrow (BM) derived endothelial progenitor cells (EPCs) play a critical role in the early stages of tumor progression and that eliminating EPCs stops cancer growth.   view more (2007-06-18)

Anti-growth factor drugs raise hope and concern for treatment of children's eye diseases
A new class of antibody drugs may provide a powerful new tool for the treatment of eye diseases in children, but specialists need to be alert for the possibility of serious side effects, according to an editorial in the August Journal of AAPOS (American Association for Pediatric Ophthalmology and Strabismus), published by Elsevier.   view more (2009-08-03)

VEGF Trap shows activity in patients with advanced ovarian cancer
Preliminary results of a randomized, international Phase II trial of VEGF Trap (aflibercept) show activity in patients with recurrent epithelial ovarian cancer (EOC) who had received three or four prior chemotherapy regimens and had become resistant to platinum-based chemotherapy agents.   view more (2007-06-04)

Radiologists use special MRI to identify brain cancer early
A special type of magnetic resonance imaging (MRI) can depict changes in blood volume in the brain that often precede cancerous transformation of brain tumors, according to a new study published in the April issue of the journal Radiology.   view more (2008-03-25)

Neuroblastoma expert reviews progress and challenges in fighting difficult pediatric cancer
Childhood cancers are fortunately rare, but among them, neuroblastoma is a special case, accounting for 7 percent of all childhood cancers, but 15 percent of childhood cancer deaths.   view more (2007-06-25)

Complex Changes in the Brain's Vascular System Occur after Menopause
Many women experience menopausal changes in their body including hot flashes, moodiness and fatigue, but the changes they don't notice can be more dangerous.   view more (2008-06-17)

A new measure for the malignancy of melanoma
Every tumor, starting from a size of a few millimeters, depends on a supply of nutrients and oxygen. Therefore, using special growth factors, it induces vascular wall cells of neighboring blood vessels to sprout new capillaries in order to get connected to the blood circulation.   view more (2009-03-12)

Taxol with avastin produces noteworthy results
The positive results of the first nationwide clinical study showing the benefits of an antiangiogenic agent in breast cancer therapy are reported in the Dec. 27 issue of the New England Journal of Medicine.   view more (2007-12-28)

The First EVGN Annual Conference: Scientists Describe A Potential Vaccine Against Heart Disease
What is the relationship between atherosclerosis and the immune response and what are the possibilities for the development of a vaccine against cardiovascular disease? What role do stem cells play in angiogenesis and what are the possible clinical applications of stems cells in cardiac recovery?   view more (2004-12-13)
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