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Study shows blood markers can help choose best dose for antiangiogenic drugs
Scientists at Sunnybrook have new information that may help to improve the use of anti-cancer drugs designed to block the growth of new blood vessels in tumors, a process called angiogenesis that is critical to tumor growth.   view more (2007-10-26)

Protein controls blood vessel formation, offers new drug target
After an injury, the body grows new blood vessels to repair damaged tissue. But sometimes too much growth causes problems, as when new blood vessels in the eyes leak, causing diabetic retinopathy and blindness if not treated.   view more (2007-12-05)

Schepens scientists are first to discover angiogenesis switch inside blood vessel cells
Scientists at Schepens Eye Research Institute, an affiliate of Harvard Medical School, are the first to discover a switch inside blood vessel cells that controls angiogenesis (new blood vessel growth).   view more (2006-05-19)

Humble yeast sheds light on promising anti-cancer drug
The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.   view more (2005-10-19)

Cancer cells forming blood vessels send their copper to the edge
New information about a link between the growth of blood vessels critical to the spread of cancer and the copper in our bodies has been discovered by researchers from the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago, using a beamline at the Advanced Photon... view more (2007-02-28)

Urine test may help monitor disfiguring birthmarks
Vascular anomalies - birthmarks caused by abnormal development of arteries, capillaries, veins or lymph vessels - can sometimes begin to progress, requiring aggressive treatment to save the child's health or vision.   view more (2005-07-06)

A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells.   view more (2008-01-17)

Northwestern researchers launch Avastin trial for pancreatic tumors
Avastin is designed to inhibit Vascular Endothelial Growth Factor (VEGF), a protein that plays an important role in tumor angiogenesis or blood vessel formation, and maintenance of existing tumor vessels.   view more (2006-02-22)

Scripps research scientists show protein accelerates breast cancer progression in animal models
These new findings could lead to a better understanding of the molecular pathogenesis of breast cancer and focus attention on PTN and its signaling pathway as possible targets for new cancer therapies.   view more (2007-06-21)

Molecular differences between early and advanced melanomas could provide new drug targets
The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found.   view more (2007-03-13)

Human vascular system in mice
The formation of new blood vessels, or angiogenesis, is an Achilles' heel of tumor growth, because tumors depend on the supply of oxygen and nutrients for survival.   view more (2008-04-15)

Bone-marrow Cell Transplantation Could Save Limbs (p 427)
Injecting a patient’s bone-marrow cells into their legs could help repair damaged circulatory systems in those with limb ischaemia, suggest authors of a trial in this week’s issue of THE LANCET. Lower limb ischaemia is due to narrowing of the arteries and is a common condition, which if... view more (2002-08-07)

Study identifies another strategy for normalizing tumor blood supply
Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy.   view more (2008-02-21)

Blood pressure drugs could help halt pancreatic cancer spread, Jefferson researchers find
Common blood pressure medications might help block the spread of pancreatic cancer, researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have found.   view more (2006-12-08)

New angiogenesis inhibitor has promise for treating deadly brain tumor
Researchers from the Massachusetts General Hospital (MGH) Cancer Center have found that AZD2171 (RECENTIN(tm)), a new angiogenesis inhibitor, can significantly reduce the size of the deadly brain tumors called glioblastomas and has the potential of improving the effectiveness of other therapeutic... view more (2007-01-17)

New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene.   view more (2008-05-09)

Fighting cancer with aspirin?
When looking for new weapons in the war on cancer, scientists should turn to their medicine cabinets for an age-old remedy-aspirin. According to scientists at the University of Newcastle (UK), aspirin has cancer-fighting effects that extend beyond already understood Cox inhibitors.   view more (2006-10-02)

MIT engineers an anti-cancer smart bomb
Imagine a cancer drug that can burrow into a tumor, seal the exits and detonate a lethal dose of anti-cancer toxins, all while leaving healthy cells unscathed.   view more (2005-07-28)

Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma.   view more (2006-06-21)

New oral angiogenesis inhibitor offers potential nontoxic therapy for a wide range of cancers
The first oral, broad-spectrum angiogenesis inhibitor, specially formulated through nanotechnology, shows promising anticancer results in mice, report researchers from Children's Hospital Boston.   view more (2008-07-02)

Vitamin A pushes breast cancer to form blood vessel cells
Researchers at Georgetown University Medical Center have discovered that vitamin A, when applied to breast cancer cells, turns on genes that can push stem cells embedded in a tumor to morph into endothelial cells. These cells can then build blood vessels to link up to the body's blood supply,... view more (2008-07-16)

New technique appears to stop abnormal blood vessel growth
A manmade protein with a tail of amino acids delivered to target cells can dramatically reduce blood vessel growth that obstructs vision or feeds a tumor, researchers have found.   view more (2005-06-01)

Case and Cleveland Clinic researchers identify molecule in age-related macular degeneration
A dart-like molecule that adheres to proteins in the eye is the key that turns on the uncontrolled growth of blood vessels, according to researchers at Case Western Reserve University and the Cleveland Clinic Cole Eye Institute.   view more (2006-09-07)

New animal study may explain why alcohol consumption increases breast cancer risk
For the first time, scientists have used a laboratory mouse model to mimic the development of human alcohol-induced breast cancer.   view more (2007-04-30)

New study shows way to avoid overtreatment in breast cancer
The numbers of women who receive adjuvant chemotherapy for breast cancer could be reduced by 30 to 40% if the results of a new molecular study are put into practice. Dr Laura van 't Veer from the Netherlands Cancer Institute told the news briefing that micro array technology* can help predict which... view more (2002-03-20)

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