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Balancing male fertility and disease resistance
An international collaboration of researchers, headed by Dr. Shiping Wang (Huazhong Agricultural University, China) has discovered that a single gene in rice regulates both male fertility and pathogen resistance, providing an unexpected genetic link between reproductive success and the disease resistance. view more (2006-05-08)
Small molecule inhibitor of cholera discovered
Just as hurricanes in the Gulf states and Guatemala have raised the risks of cholera outbreaks, researchers at Harvard Medical School have identified a new type of antibiotic against the cholera bacteria. view more (2005-10-17)
Rhode Island Hospital study finds local retail meat safe from antibiotic-resistant organisms
Rhode Island Hospital researchers report that findings from a new study of retail meat in the Providence, RI area indicate little to no presence of antibiotic-resistant bacteria. view more (2008-10-29)
Salmonella survives better in stomach due to altered DNA
Since 1995 there has been a considerable increase in the number of infections with a specific type of Salmonella bacteria transmitted via food. This type, Salmonella serovar Typhimurium DT104, is resistant to at least five different antibiotics. view more (2007-01-31)
Cells can read damaged DNA without missing a beat
Scientists have shown that cells' DNA-reading machinery can skim through certain kinds of damaged DNA without skipping any letters in the genetic "text." The studies, performed in bacteria, suggest a new mechanism that can allow bacteria to develop resistance to antibiotics. view more (2010-02-10)
How to beat superbugs
HOSPITALS in Britain will next week begin testing a drug against superbugs that mimics the antibodies produced by our immune systems. With superbugs fast developing resistance to every antibiotic we can throw at them, alternative treatments are urgently needed. In 1990, 2 per cent of Staphylococcus... view more... (2002-05-23)
Borrelia can hide in the human body for years: Even antibiotics can't always stop the bacterium
Transmitted by tick bites, the Borrelia bacterium can hide in the human body for up to several years in spite of antibiotic treatment. The patient's symptoms may be so vague that it is extremely difficult to make the connection. The research team under Professor Matti Viljanen have now developed a mouse model that can be used to locate the hidden... view more... (2005-05-20)
Same gene protects from 1 disease, opens door to another
Botanists at Oregon State University have discovered that a single plant gene can cause resistance to one disease at the same time it produces susceptibility to a different disease - the first time this unusual phenomenon has ever been observed in plants. view more (2007-08-29)
Scientists re-engineer a well-known antibiotic to counter drug resistance
The scientists replaced a single atom from the molecular structure of vancomycin aglycon, a glycopeptide antibiotic that attacks the bacteria by inhibiting cell wall synthesis, significantly increasing the drug's spectrum of activity. view more (2006-02-09)
Researchers discover how antibiotic inhibits bacterial growth
Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth. view more (2007-05-11)
Modified mushrooms may yield human drugs
Mushrooms might serve as biofactories for the production of various beneficial human drugs, according to plant pathologists who have inserted new genes into mushrooms. view more (2007-06-25)
Cloning techniques produce FDA-approved antibiotic
The successful synthesis of an antibiotic in a non-native host has provided a team of researchers at the University of Illinois at Urbana-Champaign with the potential for developing new treatments for bacterial infections. view more (2006-11-28)
A possible role for honey in the treatment of wounds
New research carried out by scientists at partner institutions UWIC (University of Wales Institute, Cardiff), University of Wales College of Medicine (UWCM) in Cardiff and the University of Waikato, New Zealand, has found sensitivity to honey of wound infecting bacteria. In a report published in the November 2002 issue of Journal of Applied... view more... (2002-11-21)
Antibiotic Could Offer Promise For Treatment Of Cystic Fibrosis
The antibiotic azithromycin could offer some benefit to people with cystic fibrosis if they do not respond to conventional treatment, suggest authors of a study in this week's issue of THE LANCET. Cystic fibrosis is a severe genetic disorder-the most commonly recessively inherited disorder in white populations. Treatment is limited, and aimed at... view more... (2002-09-25)
Better Outcome For ICU Patients After Removal Of Bacteria From Digestive Tract (pp1006, 1011)
Patients in intensive-care units (ICUs) could have better survival outcomes with the preventative use of antibiotics to remove potentially harmful bacteria from the mouth, stomach and gut. This process-known as selective decontamination of the digestive tract (SDD)-reduces the risk of respiratory-tract infection for ICU patients requiring... view more... (2003-09-24)
Researchers discover new ways to treat chronic infections
Researchers at Binghamton University, State University of New York, have identified three key regulators required for the formation and development of biofilms. The discovery could lead to new ways of treating chronic infections. view more (2009-12-21)
EARLY CASE OF RESISTANCE TO NEW ANTIBIOTIC (p 207)
A fast-track research letter published in this week’s issue of THE LANCET describes the case of a patient whose infecting bacterium developed resistance to one of the new so-called bug-busting antibiotics. Multidrug resistant bacteria have caused enormous difficulties worldwide over the past few decades. Scientists had hoped, however, that... view more... (2001-07-18)
Treatments for urinary infections leave bacteria bald, happy and vulnerable
A different approach to treating urinary tract infections (UTIs) could defeat the bacteria that cause the infections without directly killing them, a strategy that could help slow the growth of antibiotic-resistant infections. view more (2006-12-21)
Poison digs its own grave
Botrytis cinerea (grey mould) has a large arsenal of molecular pumps at its disposal to protect it against toxic substances such as antibiotics, plant defence compounds and fungicides. Dutch researcher Henk-jan Schoonbeek saw how the fungus started to pump out certain toxic substances within just 15 minutes. view more (2004-12-16)
Antibiotics may not be enough to stop recurrent gastric lymphoma caused by Helicobacter pylori
Research led by Dr. Anne Mueller at Stanford University School of Medicine demonstrates that successful eradication of Helicobacter may not prevent future aggressive gastric lymphoma since resting B cells are left behind. view more (2005-08-25)
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