Antibodies Current Events | Antibodies News | 8
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Second Generation Targeted Antibodies - It's All in the Binding
(Melbourne, May 7th) -- The overproduction, or 'overexpression', of the epidermal growth factor receptor (EGFR) is one of the most common aberrations in cancer, and subsequently agents that inhibit EGFR are among the most hotly-pursued potential products in the pharmaceutical industry. Now, just weeks after one of the first anti-EGFR antibodies,... view more... (2004-05-06)
New chemically-activated antigen could expedite development of HIV vaccine
Scientists working to develop a vaccine for the human immunodeficiency virus (HIV) report they have created the first antigen that induces protective antibodies capable of blocking infection of human cells by genetically-diverse strains of HIV. view more (2009-09-22)
High dose of flu vaccine boosts immune response in elderly
Giving people age 65 and older a dose four times larger than the standard flu vaccine boosts the amount of antibodies in their blood to levels considered protective against the flu, more so than the standard flu vaccine does. view more (2008-10-27)
Long term relief from arthritis could evolve from B-cell targeted treatments
Long term relief for arthritis sufferers could be one step closer, thanks to a study of B-cell targeted therapy published today. The study from UCL reveals a major but hitherto poorly acknowledged role for B-cells in the most common and severe form of arthritis to affect younger people. By targeting B-cells, which are part of the body's immune... view more... (2004-06-14)
MIT model could improve some drugs' effectiveness
MIT researchers have developed a computer modeling approach that could improve a class of drugs based on antibodies, molecules key to the immune system. The model can predict structural changes in an antibody that will improve its effectiveness. view more (2007-09-24)
Cholesterol-lowering Drug May Also Reduce Risk of Blood Clots
Statin drugs, commonly used to lower high cholesterol blood levels, have been shown to possibly decrease the risk for thrombotic complications of antiphospholipid syndrome (APS), a disease associated with blood clotting and recurrent fetal loss. Research conducted on animal models, has shown success in using the drug fluvastatin to inhibit the... view more... (2004-11-10)
Natural immune-control system may aid treatment of autoimmune disease and tissue rejection
The immune system's ability to police itself may offer a new method of arresting the cells responsible for autoimmune diseases such as multiple sclerosis and for the rejection of transplanted organs and tissues. view more (2007-05-18)
Whooping cough persistence traced to key toxin
A key toxin associated with whooping cough helps the germs resist the human immune system and infect vaccinated populations. view more (2005-12-19)
Researchers from 5 countries to test hygiene hypothesis with EU funding
High living standards and the life style connected to them seem to promote the development of autoimmune diseases and allergic symptoms. This has lead to the assumption that the immune system begins to overreact to the organism's own structures or to exogenous non-infectious proteins, i.e. allergens, when it does not have to work hard enough to... view more... (2008-05-28)
Vaccinate infants of hepatitis B mothers, say experts
Immunising newborn infants of mothers with hepatitis B prevents infection being transmitted from mother to child, finds a study published online by the BMJ today. view more (2006-01-27)
Vegan diet promotes atheroprotective antibodies in patients with rheumatoid arthritis
Rheumatoid arthritis is associated with an increased risk of atherosclerosis (hardening of the arteries) and cardiovascular diseases. The underlying causes are unknown, but researchers suspect that the disturbed balance of blood fats seen in patients with rheumatoid arthritis may be part of the explanation. view more (2008-03-19)
NIST, NCI, SAIC partner on new method for detecting HER2 breast cancer
Generations of mothers have served up chicken soup to remedy the common cold, but now the therapeutic fowl may find use in diagnosis as well. Researchers at the National Institute of Standards and Technology (NIST), the National Cancer Institute (NCI) and the scientific research firm SAIC recently showed how chicken antibodies may one day improve... view more... (2008-02-20)
A key antibody, IgG, links cells' capture and disposal of germs
Scientists have found a new task managed by the antibody that's the workhorse of the human immune system: Inside cells, Immunoglobulin G (IgG) helps bring together the phagosomes that corral invading pathogens and the potent lysosomes that eventually kill off the germs. view more (2006-11-14)
Secrets to antibody's success against West Nile Virus surprise scientists
A monoclonal antibody that can effectively treat mice infected with West Nile virus has an intriguing secret: Contrary to scientists' expectations, it does not block the virus's ability to attach to host cells. view more (2005-09-29)
Jefferson and Delaware researchers combine tiny nanotubes and antibodies to detect cancer
By coating the surfaces of tiny carbon nanotubes with monoclonal antibodies, biochemists and engineers at Jefferson Medical College and the University of Delaware have teamed up to detect cancer cells in a tiny drop of water. view more (2005-11-17)
Uncovering the Achilles' heel of the HIV-1 envelope
New structural details illustrate how a promising class of antibodies may block human immunodeficiency virus (HIV)-1 infection and reveal valuable clues for design of an effective HIV-1 vaccine. view more (2008-01-14)
UC Davis researchers report new molecule that targets leukemia and lymphoma cells
UC Davis Cancer Center researchers have developed a novel peptide that binds to the surface of leukemia and lymphoma cells with extremely high affinity, specificity and stability, and demonstrates remarkable promise as a tool to help image tumors and deliver anti-cancer drugs. view more (2006-06-13)
Aggressive stem cells might improve transplant outcome
Investigators at St. Jude Children's Research Hospital have demonstrated in mice a way that might reduce the time it takes for a bone marrow transplant to rebuild a child's immune system, and so reduce the risk of potentially fatal virus infections that can occur during this time. view more (2006-12-08)
Flu shot might also offer some protection against H5N1
The yearly influenza vaccine that health officials urge people to get each fall might also offer certain individuals some cross protection against the H5N1 virus, commonly known as bird flu, according to investigators at St. Jude Children's Research Hospital. view more (2007-02-14)
New technique yields more detailed picture of chromatin structure
University of Illinois researchers have developed a technique for imaging cells under an electron microscope that yields a sharper image of the structure of chromatin, the tightly wound bundle of genetic material and proteins that makes up the chromosomes. view more (2008-04-17)
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