Antibody Current Events | Antibody News | 2
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First human gets new antibody aimed at hepatitis C virus
Building upon a series of successful preclinical studies, researchers at MassBiologics of the University of Massachusetts Medical School (UMMS) today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis C virus (HCV). view more (2009-08-07)
Antibody Extends Life of Mice with Breast Cancer
A monoclonal antibody developed by researchers at the University at Buffalo has been shown to extend significantly the survival of mice with human breast-cancer tumors and to inhibit the cancer's spread to the lungs in the animals by more than 50 percent. view more (2006-12-12)
Novel antibody prevents infection by hepatitis C virus
Taking aim at a leading cause of liver failure in the United States, a team of scientists at the Massachusetts Biologic Laboratories (MBL) of the University of Massachusetts Medical School (UMMS) has developed a human monoclonal antibody that neutralizes the Hepatitis C virus (HCV). view more (2009-05-06)
Scripps Research scientists shed new light on how antibodies fight HIV
By furthering scientists' understanding of the molecular mechanisms that separate the minority of successful HIV antibodies from the majority of ineffective antibodies, the work may have implications for future attempts to design an HIV vaccine. view more (2007-09-07)
UV light improving chances of fighting cancer
Scientists at Newcastle University have developed a cancer fighting technology which uses UV light to activate antibodies which very specifically attack tumours. view more (2007-10-30)
UCLA study uncovers clues for why Graves' disease attacks the eyes
UCLA researchers have uncovered new clues that may explain why Graves' disease (GD) attacks the muscle tissue behind the eyes, often causing them to bulge painfully from their sockets, as in the late actor Marty Feldman. view more (2007-03-01)
Cancer and arthritis therapy may be promising treatment for diabetes
An antibody used to treat certain cancers and rheumatoid arthritis appears to greatly delay type 1 diabetes in mice, Yale School of Medicine researchers report in the Journal of Clinical Investigation. view more (2007-12-19)
Patient outcomes linked to biomarker levels by quantitative technology
Researchers in the Department of Pathology at Yale University School of Medicine report that when using current pathology methods of biomarker detection, the concentration of antibodies used dramatically alters the apparent relationship of biomarker level to clinical outcome. view more (2005-12-21)
Scientists glimpse a rare human antibody which protects against AIDS
Scientists have obtained their first detailed glimpse of a rare antibody, called b12, which is capable of inactivating many different strains of HIV, the virus which causes AIDS. A crystal structure of b12 has been determined by scientists working at The Scripps Research Institute, California, and the Glycobiology Institute at Oxford University,... view more... (2001-08-08)
Scripps research scientists reveal key structure from ebola virus
Described in the July 10, 2008 issue of the journal Nature, the research reveals the shape of the Ebola virus spike protein, which is necessary for viral entry into human cells, bound to an immune system antibody acting to neutralize the virus. view more (2008-07-10)
Uncovering the Achilles' heel of the HIV-1 envelope
New structural details illustrate how a promising class of antibodies may block human immunodeficiency virus (HIV)-1 infection and reveal valuable clues for design of an effective HIV-1 vaccine. view more (2008-01-14)
Adding radioimmunotherapy to chemo may help patients with lymphoma
Patients treated for follicular lymphoma, a slow-growing type of non-Hodgkin's lymphoma, may benefit from chemotherapy followed by radioimmunotherapy, according to a University of Pittsburgh Medical Center (UPMC) study presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago and published as Abstract 8005 in... view more... (2007-06-04)
Breakthrough in fight against Hendra virus
There has been a breakthrough in the fight against the deadly Hendra virus following the development of a treatment which shows great potential to save the lives of people who become infected with the virus. view more (2009-11-02)
Animal studies show promise for development of human SARS immunisation (pp 2102, 2122, 2139)
An article and research letter in this week's issue of THE LANCET provide evidence for the effectiveness of experimental SARS immunisation in animal studies. Although further research is required, these preliminary results show the potential for the development of human SARS immunisation. Alexander Bukreyev from the US National Institutes of... view more... (2004-06-23)
Antibody therapy prevents type 1 diabetes in mice
University of Pittsburgh investigators have successfully prevented the onset of type 1 diabetes in mice prone to developing the disease using an antibody against a receptor on the surface of immune T-cells. According to the investigators. view more (2007-01-09)
Antibody leads to repair of myelin sheath in lab study of multiple sclerosis and related disorders
Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system. view more (2007-10-09)
MIT model could improve some drugs' effectiveness
MIT researchers have developed a computer modeling approach that could improve a class of drugs based on antibodies, molecules key to the immune system. The model can predict structural changes in an antibody that will improve its effectiveness. view more (2007-09-24)
HIV-infected infants respond poorly to childhood vaccination
It is known that HIV-infected children who do not receive appropriate antiretroviral drugs experience immune depression, and may become susceptible to infectious diseases that would otherwise be prevented by childhood immunization. view more (2007-12-05)
Cancer drug effectively treats transplant rejections
University of Cincinnati (UC) researchers have discovered a new therapy for transplant patients, targeting the antibody-producing plasma cells that can cause organ rejection. view more (2008-12-29)
Clinical trial backs use of special yogurt to fight stomach ulcer bacteria
Results of the first human clinical studies confirm that a new yogurt fights the bacteria that cause gastritis and stomach ulcers with what researchers describe as almost vaccine-like effects, scientists in Japan will report here today at the 237th National Meeting of the American Chemical Society. view more (2009-03-23)
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