Antibody Current Events | Antibody News | 9
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Rheumatoid arthritis drug linked to serious infections and cancers
A new meta-analysis of many previous studies of TNF- (tumor necrosis factor) blocking antibodies for treatment of rheumatoid arthritis has confirmed a previously discovered increased risk for serious infection and has found that cancer also is a potential risk associated with the drugs. view more (2006-05-17)
Preventing lung scarring may extend lives of lung cancer patients
Researchers have found that using a special type of drug called a pharmaceutical monoclonal antibody to block the integrin beta6-TGF-beta pathway prevents a serious side effect of radiation therapy for lung cancer patients - pulmonary fibrosis (scarring of the lungs), thereby extending patients' lives and improving their quality of life. view more (2007-10-30)
Study shows that maintenance rituximab is useful for advanced indolent lymphoma
A new study has found for the first time that maintenance therapy with the novel antibody, rituximab (MR) following cyclophosphamide, vincristine and prednisone (CVP) therapy improves progression-free survival in patients with stage III-IV indolent lymphoma. view more (2009-03-11)
Paradigm shift: Switch for programmed cell death promotes spread of glioblastoma
Malignant tumors have usually lost their ability to destroy themselves by programmed cell death, or apoptosis. Therefore, tumors are often resistant to chemotherapy or radiation therapy, whose effect is based on forcing tumor cells to commit suicide. view more (2008-03-12)
Cancer treatment is first to directly target tumor blood vessels in patients
A clinical trial has for the first time proven that an antibody called J591 specifically targets an antigen found in high amounts on both prostate tumors and on blood vessels of all solid tumors, according to a study by medical researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City. view more (2007-03-05)
The memory of water is a reality
A special issue of the journal Homeopathy, journal of the Faculty of Homeopathy and published by Elsevier, on the "Memory of Water" brings together scientists from around the world for the first time to publish new data, reviews and discuss recent scientific work exploring the idea that water can display memory effects. view more (2007-08-02)
MIT: Extending the shelf life of antibody drugs
A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf life because they tend to clump together, rendering them ineffective. view more (2009-06-30)
Finding suggests novel ways to boost vaccination or natural defenses
Our bodies rely on the production of potent, or 'high affinity', antibodies to fight infection. The process is very complex, yet Sydney scientists have discovered that it hinges on a single molecule, a growth factor, without which it cannot function. view more (2008-07-08)
EphA2-targeted therapy delivers chemo directly to ovarian cancer cells
With a novel therapeutic delivery system, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center has successfully targeted a protein that is over-expressed in ovarian cancer cells. view more (2009-07-30)
New Developments in Angiogenic Therapy Emerging from Oxford
Angiogenesis, the growth of new blood vessels, is important in the healthy body for healing wounds and, in females, for the monthly reproductive cycle and during pregnancy. It is controlled in the body through the use of the body’s own angiogenesis inhibitors and stimulators. In certain diseases the body is unable to control blood vessel... view more... (2002-08-23)
New technique sees into tissue at greater depth, resolution
By coupling a kicked-up version of microscopy with miniscule particles of gold, Duke University scientists are now able to peer so deep into living tissue that they can see molecules interacting. view more (2008-09-18)
New cancer drug delivery system is effective and reversible
For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug must also spare healthy cells, and - ideally - its effects will be reversible, to cut short any potentially dangerous side effects. view more (2009-08-07)
Biodegradable microspheres deliver time release vaccines, stimulate different immune response
A new vaccine delivery system using microspheres of a biodegradable polymer may not only reduce the need for booster shots in some cases, but also appears to stimulate an immune response that traditional vaccines do not. view more (2007-03-01)
Risk of HIV transmission highest early in infection
New evidence suggests that the risk of HIV transmission may be highest in the early stages of infection. According to a study published in the April 1 issue of The Journal of Infectious Diseases, now available online, early infection accounted for nearly half of all transmission occurrences in an HIV-infected population in the province of Quebec,... view more... (2007-03-06)
Anthrax attack posed greater potential threat than thought
A new study shows that more people were at risk of anthrax infection in the Oct. 2001 attack on U.S. Sen. Tom Daschle's office than previously known. view more (2007-01-05)
Medimmune announces phase 2 safety data for anti-RSV antibody and national RSV surveillance results
MedImmune, Inc. today announced results from two important studies presented at the 2007 Infectious Diseases Society of America (IDSA) 45th Annual Meeting adding to the body of knowledge about respiratory syncytial virus (RSV). view more (2007-10-05)
A simplified method of giving rabies vaccine
A simplified economical method of giving rabies vaccine is just as effective as the expensive standard vaccine regimen at stimulating anti-rabies antibodies. view more (2008-04-23)
Results good for HER-2 positive breast cancer patients using trastuzumab
Researchers in the North Central Cancer Treatment Group (NCCTG) have shown that patients who receive trastuzumab at the same time as post-chemotherapy radiation treatments for HER-2 positive breast cancer have no more risk for major side effects or complications than those who do not receive the drug. view more (2006-06-06)
First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
Origen Therapeutics today announced the first published scientific report of fully functional, human sequence monoclonal antibodies (mAbs) produced in chickens. The antibodies were expressed solely in the chicken oviduct and deposited into egg white in concentrations of 1-3 milligrams per egg. view more (2005-08-29)
Chlamydia In Men Now Also Linked To Infertility - New Findings
Chlamydia infection in women has been known for some time to be linked to infertility, but Swedish research published today (Thursday 29 April) in Europe's leading reproductive medicine journal Human Reproduction[1] has found evidence that infection in men can also lessen the chance of their partners becoming pregnant. A team from Ume'å... view more... (2004-04-26)
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