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Antipsychotic Drug News | Antipsychotic Drug Current Events
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Atypical antipsychotic drugs for dementia may be associated with small increased risk of death
Patients with dementia who took atypical antipsychotic drugs had a slightly increased risk of death compared to patients who took placebo, according to a meta-analysis published in the October 19 issue of JAMA.   view more (2005-10-19)

Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk. Available antipsychotic medications treat some of the symptoms of schizophrenia, but are typically effective in only a subset of patients.   view more (2008-01-09)

Schizophrenia drugs increase risk of cardiac arrest
Patients with schizophrenia who take antipsychotic drugs are more likely to have a cardiac arrest than non-schizophrenic patients, finds a study in this week’s BMJ.   view more (2002-11-06)

Antipsychotic drug may block addiction, UIC researchers find
Researchers at the University of Illinois at Chicago have discovered that a long-approved oral antipsychotic drug can stop the addictive properties of opioid painkillers in mice.   view more (2006-02-09)

Short-term use of antipsychotics in older adults with dementia linked to serious adverse events
Older adults with dementia who receive short-term courses of antipsychotic medications are more likely to be hospitalized or die than those who do not take the drugs, according to a report in the May 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2008-05-27)

Studies look at how genes affect antipsychotic drug response
Researchers at the University of Illinois at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic medication works in adults and children and the side effects it will cause.   view more (2006-11-10)

New-generation Antipsychotic Drugs May Have Similar Neurological Side-effects To Conventional Drugs (p 1581)
Authors of a systematic review of antipsychotic drugs in this week's issue of THE LANCET highlight how the better side-effect profile of new-generation drugs may not be as substantial as previously thought when compared with conventional antipsychotics. New-generation drugs are generally more... view more (2003-05-07)

Anti-psychotic drug use in the elderly increases despite drug safety warnings
Three regulatory warnings of serious adverse events slowed the growth of use of atypical antipsychotic drugs among elderly patients with dementia, but they did not reduce the overall prescription rate of these drugs.   view more (2008-08-26)

Diabetes medication and lifestyle changes can help treat weight gain induced by antipsychotic drugs
Lifestyle intervention and the drug metformin are both effective against antipsychotic-induced weight gain, and treatment is most effective when the two therapies are combined, according to a study in the January 9/16 issue of JAMA.   view more (2008-01-09)

Second-generation antipsychotic medications appear to offer little advantage over older drugs
Among patients with schizophrenia whose medication is changed because of ineffectiveness or harmful side effects, second-generation antipsychotic drugs do not appear to offer significant benefits compared to first-generation antipsychotic drugs.   view more (2006-10-03)

Looking beyond the drug receptor for clues to drug effectiveness
Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes in how these drugs are developed and prescribed.   view more (2008-08-26)

Common treatment for methamphetamine overdose may damage brain cells
A common antipsychotic drug used in emergency rooms to treat methamphetamine overdose damages nerve cells in an area of the brain known to regulate movement, a new study shows.   view more (2007-05-30)

Weight gain induced by antipsychotic drugs can be avoided
A research team from Université Laval's Faculty of Medicine and Robert-Giffard Hospital has demonstrated that weight gain induced by the use of antipsychotic drugs-which in extreme cases can be as high as 30 kilos in only one month-can be avoided through a specially designed weight control... view more (2008-01-17)

Violence declines with medication use in some with schizophrenia
Some schizophrenia patients become less prone to violence when taking medication, but those with a history of childhood conduct problems continue to pose a higher risk even with treatment, according to a new study by researchers at Duke University Medical Center.   view more (2008-07-01)

Restrictive drug policies often cause schizophrenic patients to discontinue medication
Policies requiring authorization before physicians can prescribe newer medications to schizophrenic patients may be counter-productive. According to a new study, patients in Maine's Medicaid program who found themselves in this situation were 29% more likely to stop or disrupt medication use than... view more (2008-04-01)

Older medication may be more cost-effective for some patients with schizophrenia
A new study analyzing the economic implications of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) concludes that the older (first generation) antipsychotic medication perphenazine was less expensive and no less effective than the newer (second generation) medications used... view more (2006-12-01)

Treatment With An Antipsychotic Drug Found To Cause Changes In Metabolism Earlier Than Expected
Schizophrenia is a complex type of psychotic mental illness characterized by thoughts that are uncoupled from reality.   view more (2008-04-08)

Comparison of antipsychotic treatments in adolescents with schizophrenia
There is a wealth of scientific literature available on the treatment of adults diagnosed with schizophrenia. However, there is a paucity of data to guide the treatment of children and adolescents with schizophrenia.   view more (2008-02-29)

Antidepressant shows early promise in treating agitation and psychotic symptoms of dementia
Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia. Researchers also found that the antidepressant was associated with... view more (2007-09-10)

HOPE FOR GENETIC TESTS TO TREAT SCHIZOPHRENIA AND ASTHMA
Scientists are moving a step closer to providing treatment based on a person's genetic profile. Doctors at the Institute of Psychiatry, Kings College, London have found a way to predict the response of an antipsychotic drug called clozapine used for the treatment of schizophrenia.   view more (2000-01-04)

New details in schizophrenia treatment trial emerge
Two new studies from the Clinical Antipsychotic Trials for Intervention Effectiveness (CATIE) provide more insights into comparing treatment options, and to what extent antipsychotic medications help people with schizophrenia learn social, interpersonal and community living skills.   view more (2007-03-01)

Antipsychotic medications used to treat Alzheimer's patients found lacking
Commonly prescribed antipsychotic medications used to treat Alzheimer's patients with delusions, aggression, hallucinations, and other similar symptoms can benefit some patients, but they appear to be no more effective than a placebo when adverse side effects are considered.   view more (2006-10-12)

Estrogen relieves psychotic symptoms in women with schizophrenia
When combined with antipsychotic medications, the estrogen estradiol appears to be a useful treatment in women with schizophrenia, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2008-08-05)

New research suggests that recognising early impairments may make Alzheimer's a treatable disease
Alzheimer's Disease need no longer be a death sentence but will become more treatable, if detected in its early stages. Evidence on brain scans, in conjunction with performance on psychological test showing mild cognitive impairments (MCI) like slight memory loss, pinpoints more people at risk of... view more (1999-03-16)

Cost control measures limit patient and physician choice in psychotropic medications
A new Brandeis University study published online in Clinical Therapeutics suggests that private health plans increasingly rely on escalating copayments to manage drug costs, as opposed to administrative controls.   view more (2007-03-02)
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