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Antiretroviral Current Events | Antiretroviral News | 3

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Highly active antiretroviral therapy of similar benefit for HIV-infected injection drug users
Contrary to the belief that HIV-infected injection drug users (IDUs) receive less benefit from highly active antiretroviral therapy (HAART), new research finds little difference in the survival rate between IDUs and non-IDUs after 4-5 years of receiving HAART.   view more (2008-08-04)

Combination anti-retroviral therapies associated with reduced infections in HIV-infected children
Since the introduction of highly active antiretroviral therapies, there has been a substantial reduction of opportunistic infections and other infections in HIV-infected children, such as pneumonia and tuberculosis.   view more (2006-07-19)

Efficiency and feasibility of antiretroviral therapy in Africa demonstrated in IRD-coordinated surveys
Three-quarters of all people hit by HIV live in Sub-Saharan Africa. It is vital therefore that antiretroviral treatments, available and effective in industrialized countries, can be used for patients in Africa. Several enquiries, coordinated by the Institut de Recherche pour le Développement (IRD) are bringing proof that such treatments are... view more... (2002-07-10)

Well-armed immune cells help long-term nonprogressors contain HIV
To help develop an effective HIV vaccine, researchers are trying to better understand how the immune systems of a small minority of HIV-infected people known as long-term non-progressors (LTNPs) contain the virus naturally.   view more (2008-12-05)

Ultra deep sequencing identifies HIV drug resistance at early stage
Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations.   view more (2007-06-18)

International panel updates treatment guidelines for HIV infection
An evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.   view more (2008-08-04)

Treating HIV-infected infants early helps them live longer
Hundreds of thousands of babies around the world are born each year with HIV--more than half a million in 2006 alone.   view more (2007-07-25)

Press release ANRS, INSERM, AFSSAPS
Adverse events that were unknown so far, have recently been observed in France in children who had been exposed to antiretroviral drugs (nucleosidic inhibitors of the reverse transcriptase) during intra uterine life and postnatally to prevent mother to child transmission of HIV. The children suffer from mitochondrial dysfunctions. The mitochondry... view more... (1999-06-25)

Early administration of antiretroviral therapy can improve survival
The first antiretroviral treatments appeared in 1996. Since then, new and better drugs have been discovered that have almost turned AIDS into a chronic disease.   view more (2009-04-10)

Using hair to manage HIV/AIDS and predict treatment success
UCSF researchers have found that examining levels of antiretroviral drugs in hair samples taken from HIV patients on therapy strongly predicts treatment success.   view more (2009-03-04)

HIV measurement appears to be less reliable than thought in predicting loss of CD4 cells
Preliminary research indicates that the initial HIV RNA level in untreated HIV-infected patients appears to have little value in predicting the rate of CD4 cell count decrease.   view more (2006-09-27)

Study shows suppressing herpes virus may reduce infectiousness of HIV
A recent study of men co-infected with herpes simplex virus type 2 (HSV-2) and HIV revealed that drugs used to suppress HSV decrease the levels of HIV in the blood and rectal secretions, which may make patients less likely to transmit the virus.   view more (2007-11-16)

U of M study shows why treatment isn't effective for HIV
University of Minnesota researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients.   view more (2008-08-06)

HIV in the nervous system - still a cause for concern?
HIV infection can be controlled with antiretroviral drugs, but it cannot be wiped out. New evidence suggests that low levels of HIV may still lead to long-term brain damage and dementia, scientists heard today (Tuesday 09 April 2002) at the spring meeting of the Society for General Microbiology at the University of Warwick. "There is concern for... view more... (2002-04-02)

Genetic Testing Could Identify HIV Patients At Risk Of Hypersensitivty To HIV Drug (pp 722, 727)
HIV patients at risk of a potentially fatal hypersensitive reaction to the antiretroviral drug abacavir could be identified by genetic testing before drug therapy has started, suggest authors of a fast-track study in this week's issue of THE LANCET. The use of the HIV antiretroviral drug abacavir, a potent HIV-1 nucleoside-analogue... view more... (2002-02-28)

Integrating antiretroviral therapy with TB treatment for co-infections reduces mortality
A South African treatment study conducted by researchers in the Department of Epidemiology at the Mailman School of Public Health shows that mortality among TB-HIV co-infected patients can be reduced by a remarkable 55%, if antiretroviral therapy (ART) is provided with TB treatment at the same time.   view more (2008-10-17)

New Therapeutic Vaccine for HIV/AIDS Eliminates Needles and Excessive Toxicity
DermaVir, a novel treatment for HIV/AIDS, offers a new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys. This treatment possibly offers a new, non-invasive option for... view more... (2005-01-06)

UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery
UC Davis researchers have discovered that the human immunodeficiency virus, the virus that causes AIDS, is able to survive efforts to destroy it by hiding out in the mucosal tissues of the intestine.   view more (2006-07-31)

Abacavir Could Play Important Future Role In Treatment Of Children With HIV-1 (p 733)
Results of the Paediatric European Network for Treatment of AIDS (PENTA) 5 Trial, published in this week's issue of THE LANCET, suggest an important future role for the drug abacavir in the treatment of children with HIV-1. Antiretroviral HIV-1 drug treatment for adults in more-developed countries usually involves combination therapy with two... view more... (2002-02-28)

Anti-HIV drugs unlikely to stop HIV spread
Researchers believe antiretroviral therapy (ART) will not be effective in stopping HIV epidemics even if it is made universally available in poorer countries, and that widespread use could even lead to an increase in the numbers infected with HIV.   view more (2006-03-14)
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